Purpose: This study was done to determine the effects of a neurofeedback program on brain function and stress in occupational high school students. Method: A nonequivalent control group, non-synchronized with pre-posttest design was used with 62 students. Data collection was done from July to December, 2007. The neurofeedback training was given for 30 minutes at a time, three times a week for 12 weeks. Brain function was measured by brain waves in the frontal lobes of the students and analyzed by eight brain quotients characterizing patterns of EEG rhythms. The instrument used to measure stress was a scale for stress from regular daily life. Results: After neurofeedback training, the level of brain quotients in students in the experiment group increased(t=2.36, p<.05) and the level of stress decreased(t=-3.59, p<.001). Conclusion: The results of the study suggested that a neurofeedback program is effective for brain function improvement and stress reduction in high school students. Therefore, the conclusion of this study is that neurofeedback programs can be useful to increase brain function and decrease stress in occupational high school students.