This paper proposes a semi analytical model to describe the pore structure of concrete by a set of simple equations. The relationship between the porosity and the microstructure of concrete has been considered when constructing the analytical model. The microstructure includes the interface transition zone (ITZ) between aggregates and cement paste. The predicting model of porosity was developed with considering the ITZ for various mixing of mortar and concrete. The proposed model is validated by the rapid experimental programs. Although the proposed model is semi-analytical and relatively simple, this model could be reasonably utilized for the durability design and adapted for predicting the service life of concrete structures.