This study aims at clarifying the influence that color, tone, dot size, the combination of area ratios exercise on the harmony in dot necktie, and revealing the harmony differentiation according to the cues of various factors for pattern design. The conclusion is drawn as below, in the result that the cues which can exercise influence on the harmony of dot necktie, was analyzed by 54 stimuli. In the result of analysis of variance in order to clarify the influence which color, tone, dot size, and color area ratio exercise on dot necktie harmony, color and dot size operate appeared to be independent cues which exercise significant influence with main effect. In the result of the harmony difference analysis on color, tone, dot size, and color area ratio combination by multiple comparison, the cyan color in vivid tone was estimated to be most inharmonious in the analysis by color and tone. Viewing the harmony difference according to color and dot size, the dot size of 0.5cm in cyan was perceived to be most harmonious. Viewing the harmony difference according to color and color area ratio combination, both magenta and cyan were estimated to be positive, regardless of area ratio combination, and particularly, the case that the background was in cyan and the dots were in grey was perceived more harmonious compared to the contrary case. Viewing the harmony difference according to tone and dot sizes, the case when the dot sizes were 0.5cm, was perceived to be most positive, regardless of tone. Viewing the harmony difference according to color area ratio combination and tone, the case that the chromatic colors, cyan, magenta, and yellow was used as background, was estimated to be more harmonious, compared to the case that the achromatic color, grey was used as background. Viewing the harmony difference according to dot size and color area ratio combination, in case that the dots were in chromatic color and the background was in grey, the harmony showed difference by dot size, and the case of the dot size of 0.5cm was estimated to be most harmonious.