Recently, alternative energy resources have emerged considerably due to the high oil prices and environment problems. Deep sea water that is one of the natural energy sources can be one of the attractive solutions to reduce the environment problems, and there are already a few examples in some developed countries. In this study, cooling system of deep sea water using heat exchangers of two hotels, located in near Haeundae Bay in Busan, have been analyzed on the quantity of electricity and gas use comparison between existing cooling system and deep seawater cooling system by using E-Quest simulation program. The results of the study showed that the Hotel A approximately saves 370 millions won per year, and the Hotel B saves 248 millions won per year. It means that the cooling system by using deep sea water has great worth to reduce the ratio of fuel sources.