In the computing environment with heterogeneous resources, a job scheduling model is necessary for effective resource utilization and high-speed data processing. And, the job scheduling model has to cope with a dynamic change in the condition of resources. There have been lots of researches on resource estimation methods and heuristic algorithms about how to distribute and allocate jobs to heterogeneous resources. But, existing researches have a weakness for system compatibility and scalability because they do not support the standard language. Also, they are impossible to process jobs effectively and deal with a variety of computing situations in which the condition of resources is dynamically changed in real-time. In order to solve the problems of existing researches, this paper proposes a semantic computing-based dynamic job scheduling model that defines various knowledge-based rules for job scheduling methods adaptable to changes in resource condition and allocate a job to the best suited resource through inference. This paper also constructs a resource ontology to manage information about heterogeneous resources without difficulty as using the OWL, the standard ontology language established by W3C. Experimental results shows that the proposed scheduling model outperforms existing scheduling models, in terms of throughput, job loss, and turn around time.