민들레 꽃, 잎, 뿌리, 전초의 부위별 항산화성과 생리활성을 탐색하기 위해 열수 추출물에서 총 플라보노이드와 총폴리페놀 함량을 측정하였으며 항산화활성 그리고 tyrosinase 억제활성을 분석하였다. 총 플라보노이드 및 폴리페놀 함량은 다른 부위보다 꽃 추출물에서 32.91 mg/g, 49.31 mg/g으로 가장 높았다. 전자공여능은 1 mg/mL의 농도에서 꽃, 잎 그리고 전초 추출물이 각각 87.07%, 87.66%, 81.06%를, 뿌리 추출물은 66.20% 나타내었으며 농도 의존적으로 활성이 증가되었다. SOD 유사활성능은 1.0 mg/mL의 농도에서 부위별 추출물이 9.07~10.97%를 나타내었다. pH 1.2 조건에서 측정한 아질산염 소거능은 1 mg/mL의 농도에서 꽃과 잎 추출물이 각각 36.34%, 38.16%로 전초와 뿌리보다 높았다. Tyrosinase 저해활성은 1 mg/mL의 농도에서 잎추출물이 34.19%로 가장 높았으며 전초와 뿌리 추출물에서도 20% 이상의 저해활성이 나타났다. 이상의 결과 민들레 꽃, 잎, 뿌리 및 전초 열수 추출물이 우수한 항산화 활성을 지녀 이를 기능성 건강식품의 소재로 활용할 수 있다고 사료된다.
This study was conducted to examine antioxidative and physiological activities of water extracts from different parts (flower, leaf, root, and the whole plant) of Taraxacum officinale. The water extracts from different parts were measured to obtain total flavonoids content, total polyphenol content, electron donating ability, SOD-like activity, nitrite-scavenging ability and tyrosinase inhibition effects. Total flavonoids and total polyphenol contents in flower extract were 32.91 mg/g and 49.31 mg/g, respectively, which were much higher than those of any other parts. The electron donating abilities of flower, leaf, the whole plant, and root extracts were 87.07%, 87.66%, 81.06% and 66.20%, respectively at a concentration of 1 mg/mL. The activities increased in a dose-dependent manner. The SOD-like activity of water extracts from different parts showed 9.07~10.97% at a concentration of 1 mg/mL. The nitrite-scavenging abilities of flower and leaf extracts measured at pH 1.2 were 36.34% and 38.16%, respectively at a concentration of 1 mg/mL. Tyrosinase inhibition activity of the leaf extract at a concentration of 1 mg/mL was the highest (34.19%) and that of the whole plant and root extracts was shown to be more than 20%. These results suggest that water extracts from different parts of Taraxacum officinale could be used as an antioxidative functional food source.
