The purpose of this study is to analyze the influence of DISC behavior pattern, stress-managing method, and the stress level on job attitude of hospital Employees, and to provide suggestions for effective human resources management in hospital settings. First, the research suggested emotional or aversive stress-managing method had significant influence to the stress level, whereas DISC behavior patterns did not. Second, to the job satisfaction, Influence, Compliance and Steadiness of DISC behavior patterns, challenging or aversive stress-managing method, and the stress level showed immediate meaningful effect. Third, for the system immersion, challenging or emotional ress-managing method as well as the job satisfaction showed direct influence. Especially, the challenging method had not only a direct but an indirect effect through mediating job satisfaction.