Photomosaic is a method of representation an input image in forms of mosaics by a set of small tile images. Generally, equal rectangular tiles are used in photo mosaics. Therefore, there are limitations to expression of mosaic according to characteristic of images. In this paper, photo mosaics using quad-tree structure is proposed to create tiles in varies sizes. Initially, color variance per each level of an input image is computed using the mipmap of graphic hardware. Depending on the value of Valiance, the input image is divided into tiles in varies sizes. Each tile finds the most similar reference image and replaces with it. As a result, the method provides another pictorial effectiveness by dividing the input image into tiles in varies sizes depending on color held by the input image. In addition, whole processing is done on the graphic hardware and thereby we achieve faster performance.