- 비타민 K의 골 건강 증진 효과
- Beneficial effect of vitamin K on bone health
- ㆍ 저자명
- 장영호,Jang. Young-Ho
- ㆍ 간행물명
- 한국치위생학회지
- ㆍ 권/호정보
- 2011년|11권 4호|pp.419-426 (8 pages)
- ㆍ 발행정보
- 한국치위생학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
Originally, vitamin K was defined as a factor for blood coagulation. Now more attention is focused on vitamin K for bone metabolism and bone health. Vitamin K is a coenzyme for glutamate carboxylase which converts glutamate residues to ${gamma}$-carboxyglutamate(Gla) residues. Gla residues have calcium binding ability and bound to hydroxyapatite crystals in bone. Vitamin K promotes the carboxylation of osteocalcin and matrix Gla-protein, vitamin K-dependent proteins and improves bone mineral density and bone mass. Vitamin K deficiency causes reductions in bone mineral density and increases the risk of osteoporotic bone fractures, resulting from undercarboxylated osteocalcin. This paper is to provide a brief information of vitamin K and its role in bone health.