Purpose: This study was conducted to examine the effects of group music therapy on psychiatric symptoms and interpersonal relationship in patient with schizophrenia. Methods: This was a quasi-experimental study with nonequivalent control group pretest-posttest design. The subjects were 63 patients with schizophrenia at S psychiatric sanatorium in D city. Thirty two patients were assigned to experimental group and thirty one patients were assigned to control group. Data were collected from August 4 to September 25, 2011. The group music therapy was conducted for 60 minutes, 8 times per week for 4 weeks. Data were analyzed using descriptive statistics, $x^2$ test and t-test with SPSS/WIN 19.0 version. Results: Experimental group receiving group music therapy showed significant improvements of psychiatric symptoms and interpersonal relationship. Conclusion: The study results indicate that group music therapy is an effective intervention program in improving psychiatric symptoms and interpersonal relationship of patients with schizophrenia.