This paper describes energy loss in a pipe line of refuse collecting system. Analysis of energy loss in a pipe line is the decisive factor in a design of refuse collecting system. Using the results of energy loss analysis, we can determine the power of turbo-blower. The flow characteristics of the pipe line with refuse bags were analyzed by three-dimensional CFD. The refuse bag is modeled by using the shape obtained from profile measurement. Friction factors were calculated with changing the refuse bag size, mixing ratio and Reynolds number. And drag coefficients were calculated using the CFD results. From the results we can calculate energy loss in a pipe line of refuse collecting system and predict the capacity of turbo-blower.