Objectives : To broaden understanding about meridian tendino-musculature acupuncture on nerve compression syndrome of upper limbs and to evaluate the effect of meridian tendino-musculature acupuncture on nerve compression syndrome of upper limbs. Methods and Results : From June 1st to Oct. 31th, the patients were outpatients for treatment of nerve compression syndrome of upper limbs in department of acupuncture and moxibustion, traditional Korean medical hospital, Semyung University and treated with meridian tendino-musculature acupuncture. To evaluate the effect of meridian tendino-musculature acupuncture, thickness of muscle by medical skinfold caliper, coding result(arbitary values used to evaluate results) and VAS(Chief complain) were used. As a result, muscle atropy and symptoms are improved remarkably. Conslusions: Meridian tendino-musculature acupuncture was found to be helpful to patients who wish to recover from their muscle atropy and symptoms of upper limbs. In order to make this meridian tendino-musculature acupuncture more available, we should pay more attention to improving treatment appliance and acupuncture technique.