Recently ultra high strength steels(UHSS) has been widely applied to the structural or safety components in the automotive industry. Specially, hot stamping boron steel 22MnB5 has shown the crash-resistant characteristics when applying to bumpers and pillars. Lap joint Laser welding of the hot stamped and die quenched sheets of Boron steel was carried out using 3kW Nd/YAG laser. The appropriate Lap joint laser welding conditions were founded separately for four lap joint combinations. The lower sheest is a hot stamped sheet in common and the upper sheet is selected among the hot stamped steel and high strength steels such as SPCC, 370MPa, and 590MPa grade high strength steels. Cross bead sections and local hardening and softening were observed as well as tensile-shear test results.