Objectives: The purpose of this study was to examine health information seeking behavior of people with cancer in terms of information seeking or avoiding behavior and the differences of the two groups in demographic and disease variables. Methods: Data were collected from October 21 to December 5 in 2013 from out-patient clinics of a university affiliated hospital in Suwon, Korea. One hundred (100) patients with cancer were participated in this study. Health Information National Trends Survey Questionnaires (National Cancer Institute, 2007) was used. Results: Three quarters (n=77) of the participants were in health information seeking group while 23% were in health information avoiding group. Participants who were female, higher education were more likely to seek health information than their counter parts. Among participants, a considerable number of cancer patients intentionally avoided information due to either the lack of accessibility of information source or the lack of credibility of information from the sources. Conclusion: Significant differences in gender and educational level were found in the two groups. Different approaches for both groups were necessary to increase information seeking behavior. And barriers of the information avoiding group should be considered in designing interventions to fill the gap between seekers and avoiders.