The objective of this study is to estimate soil loss in the buffer zone of Guem river with future climate change simulation. Revised Universal Soil Loss Equation (RUSLE) model was used for the estimation of soil loss at the buffer zone of Guem river. As results of simulations, the area of the maximum soil loss potential was estimated as the Cheongsung-myeon Okchun-gun Chungcheongbuk-do. The soil losses were estimated to be 106.67 and 103.00 ton/ha/yr for the 2020 segi (2015-2025) and 2040 segi (2035-2045) in the Cheongsung-myeon area, respectively. Also, the estimated average values of soil losses in the Cheongsung-myeon with future climate change was 110.78 ton/ha/yr.