How to protect the environment without sacrificing the human environment and economy at the level of region is on of the most difficult issues of recent times. The dynamic Interactions between economic activities and environmental pollution control activities determine whether social welfare is increased of decreased by such activities and provides a basis for saying whether they help or hurt the economy. Bureaucratic Approach of Local government has failed, and an Impetus has arisen to develop new tools of analysis, useful for finding policy leverages focused on sustainability. This paper focus on understanding dynamic relationships between regional economic system and environmental system, and presenting possible framework for finding policy leverages in dynamic interaction behaviors. The case, selected in this study, is Nacdong river regions case, which is related many meaningful issues about sustainable development： two big metropolitan government and dwellers have different opinion with regard to construction of large scale Industrial pack, drinking water supply, and environment model consisting of three sectors： regional economy sector, river pollution and drinking water sector, environmental protection and investment policy sector Finally, this paper deal with how to link policy leverage to causal loop structure for the sustainable development of two regions.