The purpose of this study is to re-conceptualize EIU as a framework having global spirit of the 21st century and to develop a new holistic pedagogy applicable to various education fields. In order to achieve this goal, an extensive literature review, Delphi survey, focus group interview with domestic and foreign EIU experts, and field participation study were implemented. Through this study, we developed a holistic pedagogy for EIU in the 21st century. The followings are the findings and conclusions of this study. First, the aim of EIU in the 21st century is ‘to cultivate glocal citizenship’. Today, globalization is being achieved through interactions on various levels; that is, between world and local, between regions, countries, individuals, and civil societies. Because of this periodical change, EIU in the holistic model employs both global and local (glocal) perspectives in its aim. Second, EIU ultimately aims at cultivating ‘citizens’ who can embrace various cultures of the world, acknowledge diversity, try to coexist with the natural environment through recognizing a mutual relationship. Holistic education and UNESCO s four learning pillars are used for a new practice of EIU. Third, specific educational objectives and contents are presented for the holistic pedagogy of EIU. The educational objectives are set in four areas: knowledge, skill, attitude/value, and action. And the contents of education are developed to include three topics: glocal provision, glocal conscientization, global issues. In addition, a new learning model is presented connecting the three main contents with four learning pillars, and this learning model is designed to have flexibility and openness depending regional situation, time situation and learner s situation. Fourth, as for the teaching approach to cultivate glocal citizenship, critical thinking, active participation/ inclusion, cooperative attitude, transformational approaches are suggested. It is expected that the development of a holistic model for EIU based on the re-conceptualization of EIU in the 21st century will contribute to the development of a more innovative approach for international exchange, global solidarity, global supporting activities, and EIU training programs as well as for formal and non-formal school curriculum for EIU.