Obesity is associated with menstrual cycle disorder. The aim of this study was to investigate the clinical effect of the obesity therapy with Korean herbal medicine (KHM) on obese female patient with oligomenorrhea or amenorrhea. This is a retrospective observational study performed on obesity patients with oligomenorrhea or amenorrhea. Nine patients were treated with KHM and lifestyle management at least 2 months. During the treatment,\nbody weight, body mass index (BMI), percent body fat (PBF) and menstrual cycle length were checked afterwards. Body weight, BMI, and PBF of the patients were decreased during treatments. Five of 9 subjects recovered to normal menstrual cycle. Two subjects improved menstrual cycle. The other subjects remained at oligomenorrhea or amenorrhea. This study shows that the obesity therapy including KHM could be effective to improve menstrual cycle on obese patient. Further large scale studies are necessary for more evidences.