To investigate the relationship between craniofacial growth and bone maturity of the hand wrist in normal occlusion, the author took cephalogram and handwrist radiogram of 391 students (male 192, female 199) and assessed the measurements of cephalogram according to skeletal maturity stages of the hand and wrist. In this study, four skeletal stages and 36 linear, angular measurements of the cephalometrics were selected. In hand-wrist X-ray the bones used to determine skeletal maturity were the middle phalanges of the third finger, and distal epiphysis of the radius. In cephalogram, the landmark used to measure the angle and length were N, S, Po , Ar., Go., Me, Gn., Pog, Point B, Point A, ANS, PNS, Or, U1, L1, U6, L6 etc. The results were as follows, 1. The table of mean, standard deviation, p-value from measurements were made in each group and both sex. 2. The increased measurements according to skeletal maturity were anterior cranial bese length, posterior cranial base length, ramus height, anterior facial height, posterior facial height, L1 to mandibular plane (mm), facial plane angle. In contrast to, decreased measurements were gonial angle, facial cnvexity and facial plane angle. 3 Denture pattern measurements (IMPA, FMIA, occlusal plane to Go-Gn, interincisal angle, U1 to SN plane, U1 to SN plane, U1 to facial plane, L1 to facial plane etc) had nothing to do with skeletal maturity. 4. Skeletal maturity had close relationship with craniofacial growth, but had little to do with tooth development.