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91.

EFFECTS OF NITRIC OXIDE SYNTHASE INHIBITORS ON OSTEOCLAST-LIKE CELL FORMATION

Seung-Kyu Ahn, Jung-Kun Kim, Kyung-Suk Cha 대한치과교정학회 The Korean Journal of Orthodontics 8 Pages

대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 6호 7 715-722 (8 pages)

Seung-Kyu Ahn, Jung-Kun Kim, Kyung-Suk Cha 저
...
- 무료
in cultures of chick embryo bone marrow. 2. Nitric oxide synthase inhibitors(NOSI ; N-NMA, N-NAME) stimulated the osteoclast-like cells in cultures of chick embry bone marrow. 3. 1,25-dihydroxyvltamine D³ and nitric oxide synthase inhibitors did not appear to have additive effect on the generation of TRAP-positive MNCs. These results suggest that nitric oxide synthase inhibitors may stimulate the osteoclast-like multinucleated cell formation and fusion in cultures of chick bone marrow.
92.

EFFECTS OF SODIUM NITROPRUSSIDE ON THE FORMATION AND ACTIVATION OF THE OSTEOCLAST IN CULTURE

Young-Jae Yoo, Jung-Kun Kim, Kyung-Suk Cha 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages

대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 6호 6 705-714 (10 pages)

Young-Jae Yoo, Jung-Kun Kim, Kyung-Suk Cha 저
...
- 무료
Due to the great deal of effort that has gone into the study of osteoclastic differentiation and activation over the last few decades, the mechanisms of these two events have been discovered gradually. Nitric oxide(NO-), which is produced from arginine by a nitric oxide synthase, opened up a new area of biological research. Recently, it has been reported that NO- is produced by osteoblasts stimulated by lipopolysaccharide and several other cytokines. In this study, the effect of sodium...
93.

포스트 디지털 시대를 위한 음악교육의 과제 - 기술과 예술에 대한 철학적 고찰을 중심으로 -

최진경 한국음악교육학회 음악교육연구 23 Pages

한국음악교육학회 음악교육연구 2021, 제 50권 제 4호 8 175-197 (23 pages)

최진경 저
...
- 5,200원
본 연구의 목적은 포스트 디지털 시대를 위한 음악교육의 과제를 탐색하는 것에 있다. 포스트 디지털이란 디지털과 아날로그의 공존 속에서 인간을 바라보는 것이므로, 포스트 디지털 시대를 위한 음악교육의 과제는 ‘인간과 기술의 공존을 위하여 음악교육이 어떻게 이루어져야 하는가?’라는 물음에 대한 답을 찾는 것이다. 이를 위하여 연구자는 기술과 예술에 대하여 철학 적 논의를 펼친 소크라테스, 플라톤, 아리스토텔레스 그리고 하이데거의 사유를 종합하여 포스 트 디지털 시대를 위한 음악교육의 과제를 도출하였다....
94.

Suggestion of Teaching and Learning Model based on the Thinking Process in Barbara McClintock s Research

Jae-Kwon Kim 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 17 Pages

한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2017, 제 7권 제 1호 2 9-25 (17 pages)

Jae-Kwon Kim 저
...
- 4,600원
95.

Extracellular acidity enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis via DR5 in gastric cancer cells

Ran Hong, Song Iy Han 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 5 513-523 (11 pages)

Ran Hong, Song Iy Han 저
...
- 4,000원
The tumor microenvironment greatly influences cancer cell characteristics, and acidic extracellular pH has been implicated as an essential factor in tumor malignancy and the induction of drug resistance. Here, we examined the characteristics of gastric carcinoma (GC) cells under conditions of extracellular acidity and attempted to identify a means of enhancing treatment efficacy. Acidic conditions caused several changes in GC cells adversely affecting chemotherapeutic treatment. Extracellular...
96.

Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel

HyangMiLee, OkHeeChai, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 8 71-80 (10 pages)

HyangMiLee, OkHeeChai, SangJuneHahn, BokHeeChoi 저
...
- 3,000원
In patients with epilepsy, depression is a common comorbidity but difficult to be treated because many antidepressants cause pro-convulsive effects. Thus, it is important to identify the risk of seizures associated with antidepressants. To determine whether paroxetine, a very potent selective serotonin reuptake inhibitor (SSRI), interacts with ion channels that modulate neuronal excitability, we examined the effects of paroxetine on Kv3.1 potassium channels, which contribute to high-frequency...
97.

Ethyl linoleate inhibits α-MSH-induced melanogenesis through Akt/GSK3β/β-catenin signal pathway

Gyeong-AKoSomiKimCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 6 53-61 (9 pages)

Gyeong-AKoSomiKimCho 저
...
- 3,000원
Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent. In this study, we investigated the effect of ethyl linoleate on the melanogenesis and the mechanism underlying its action on melanogenesis in B16F10 murine melanoma cells. Our results revealed that ethyl linoleate significantly inhibited melanin content and intracellular tyrosinase activity...
98.

Resveratrol raises in vitro anticancer effects of paclitaxel in NSCLC cell line A549 through CO X-2 expression

FanhuaKong, RunqiZhang, XudongZhao, GuanlinZheng, ZhouWang, PengWang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 2 465-474 (10 pages)

FanhuaKong, RunqiZhang, XudongZhao, GuanlinZheng, ZhouWang, PengWang 저
...
- 3,000원
The aim of this study was to determine the raising anticancer effects of resveratrol (Res) on paclitaxel (PA) in non-small cell lung cancer (NSCLC) cell line A549. The 10 µg/ml of Res had no effect on human fetal lung fibroblast MRC-5 cells or on A549 cancer cells and the 5 or 10 µg/ml of PA also had no effect on MRC-5 normal cells. PA-L (5 µg/ml) and PA-H (10 µg/ml) had the growth inhibitory effects in NSCLC cell line A549, and Res increased these growth inhibitory...
99.

MDL-12330A potentiates TRAIL-induced apoptosis in gastric cancer cells through CHOP-mediated DR5 upregulation

Sung-ChulLimSongIyHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 5 397-405 (9 pages)

Sung-ChulLimSongIyHan 저
...
- 3,000원
drug in gastric carcinoma (GC) cell lines. In these GC cells, MDL-12330A reduced cell viability and induced cell death in a concentration-dependent manner. At a moderate concentration (~20 μM), MDL-12330A mainly induced apoptotic death whereas at concentrations greater than 20 μM, it increased non-apoptotic cell death. The induction of apoptosis was at least partially regulated by CHOP-mediated DR5 upregulation, as detected by immunoblotting and gene interference assays. More importantly, low...
100.

The oncogenic effects of p53-inducible gene 3 (PIG3) in colon cancer cells

Seon-JooPark, HongBeumKim, JeehoKim, SanggonPark, SeokWonKim, Jung-HeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 15 267-273 (7 pages)

Seon-JooPark, HongBeumKim, JeehoKim, SanggonPark, SeokWonKim, Jung-HeeLee 저
...
- 3,000원
human colon cancer cell lines compared to normal colonderived fibroblasts. Therefore, we attempted to elucidate the functional role of PIG3 in colon cancer. PIG3 overexpression increases the colony formation, migration and invasion ability of HCT116 colon cancer cells. Conversely, these tumorigenic abilities were significantly decreased in in vitro studies with PIG3 knockdown HCT116 cells. PIG3 knockdown also attenuated the growth of mouse xenograft tumors. These results demonstrate that PIG3 is...

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