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91.

A Computational Model of Cytosolic and Mitochondrial [Ca2＋] in Paced Rat Ventricular Myocytes

JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 23 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.4 5 217-239 (23 pages)

JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 저
...
- 5,200원
as well as in cytosol. As L-type Ca2＋ channel has key influence on the amplitude of Ca2＋-induced Ca2＋ release, the relation between stimulus frequency and the amplitude of Ca2＋ transients was examined under the low density (1/10 of control) of L-type Ca2＋ channel in model simulation, where the relation was reversed. In experiment, block of Ca2＋ uniporter on mitochondrial inner membrane significantly reduced the amplitude of mitochondrial Ca2＋ transients, while it failed to affect the...
92.

The Effects of Tramadol on Electroencephalographic Spectral Parameters and Analgesia in Rats

Hwan-SooJang, Il-SungJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 12 191-198 (8 pages)

Hwan-SooJang, Il-SungJang, Maan-GeeLee 저
...
- 3,000원
and electroencephalographic (EEG) spectral parameters were compared in rats. Saline or tramadol 5, 10, 20 or 40 mg/kg was administered. The degree of analgesia was evaluated by tail-flick latency, and the degree of seizure was measured using numerical seizure score (NSS). Additionally, band powers, median power frequency and spectral edge frequency 95 were measured to quantify the EEG response. All doses of tramadol produced spike-wave discharge. Tramadol significantly and dose-dependently...
93.

Effects of Zinc on Spontaneous Miniature GABA Release in Rat Hippocampal CA3 Pyramidal Neurons

Byung-JuChoi, Il-SungJang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.2 1 59-64 (6 pages)

Byung-JuChoi, Il-SungJang 저
...
- 3,000원
The effects of Zn2⁢ on spontaneous glutamate and GABA release were tested in mechanically dissociated rat CA3 pyramidal neurons which retained functional presynaptic nerve terminals. The spontaneous miniature excitatory and inhibitory postsynaptic currents (mEPSCs and mIPSCs, respectively) were pharmacologically isolated and recorded using whole-cell patch clamp technique under voltage-clamp conditions. Zn2⁢ at a lower concentration (30μM) increased GABAergic mIPSC frequency without...
94.

Morphine-induced Modulation of Nociceptive Spinal Dorsal Horn Neuronal Activities after Formalin-induced Inflammatory Pain

JooMinPark, KangWuLi, SungJunJung, JunKim, SangJeongKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 2 77-86 (10 pages)

JooMinPark, KangWuLi, SungJunJung, JunKim, SangJeongKim, 저
...
- 3,000원
In this study, we examined the morphine-induced modulation of the nociceptive spinal dorsal horn neuronal activities before and after formalin-induced inflammatory pain. Intradermal injection of formalin induced time-dependent changes in the spontaneous activity of nociceptive dorsal horn neurons. In naïve cats before the injection of formalin, iontophoretically applied morphine attenuated the naturally and electrically evoked neuronal responses of dorsal horn neurons. However, neuronal...
95.

Role of Stretch-Activated Channels in Stretch-Induced Changes of Electrical Activity

JaeBoumYoum, Su-HyunJo, ChaeHunLeem, Won-KyungHo, YungE. 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 6 33-41 (9 pages)

JaeBoumYoum, Su-HyunJo, ChaeHunLeem, Won-KyungHo, YungE. 저
...
- 3,000원
We developed a cardiac cell model to explain the phenomenon of mechano-electric feedback (MEF), based on the experimental data with rat atrial myocytes. It incorporated the activity of ion channels, pumps, exchangers, and changes of intracellular ion concentration. Changes in membrane excitability and Ca2⁢ transients could then be calculated. In the model, the major ion channels responsible for the stretch-induced changes in electrical activity were the stretch-activated channels (SACs)....
96.

Muscarine M2 Receptor-mediated Presynaptic Inhibition of GABAergic Transmission in Rat Meynert Neurons

Il-SungJangNorioAkaike 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.2 1 63-70 (8 pages)

Il-SungJangNorioAkaike 저
...
- 3,000원
Cholinergic modulation of GABAergic spontaneous miniature inhibitory postsynaptic currents (mIPSCs) by the activation of muscarine receptors was investigated in mechanically dissociated rat nucleus basalis of the Meynert neurons using the conventional whole-cell patch recording configuration. Muscarine (10μM) reversibly and concentration-dependently decreased mIPSC frequency without affecting the current amplitude distribution. Muscarine action on GABAergic mIPSCs was completely blocked by...
97.

Relatoinship between Sarcoplasmic Reticular Calcium Release and Na+-Ca2+ Exchange in the Rat Myocardial Contraction

Eun-GiKim, SoonJinKim, ChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 4 197-210 (14 pages)

Eun-GiKim, SoonJinKim, ChangMannKo 저
...
- 4,300원
Suppressive role of Na⁢-Ca2⁢ exchange in myocardial tension generation was examined in the negative frequency-force relationship (FFR) of electric field stimulated left atria (LA) from postnatal developing rat heart and in the whole-cell clamped adult rat ventricular myocytes with high concentration of intracellular Ca2⁢ buffer (14 mM EGTA). LA twitch amplitudes, which were suppressed by cyclopiazonic acid in a postnatal age-dependent manner, elicited frequency-dependent and...
98.

흰쥐에서 Chloramphenicol에 의해 유도된 불면에 대한 Amitriptyline의 효과

박수아, 한진희, 김정수, 이성필 대한신경정신의학회 신경정신의학 8 Pages

대한신경정신의학회 신경정신의학 1999, 제 38권 제 3호 17 630-637 (8 pages)

박수아, 한진희, 김정수, 이성필 저
...
- 3,000원
연구목적： 저자들은 흰쥐에서 항생제인 chloramphenicol을 투여한 후 수면의 변화 양상을 알아보고, 삼환계 항우울 제의 하나인 amitriptyline를 투여하여 항생제에 의해 유도된 불면증에 대한 항우울제의 효과를 조사하고자 하였다. 방 법： 실험동물로는 체중 270∼300g의 Sprague-Dawley 수컷 흰쥐 11마리를 사용하였고, 실험군(5마리)과 대조 군(6마리)으로 나누고 뇌파 측정 장치를 부착시킨 후 3일간(baseline, 1일, 2일) 연속적으로 수면-각성활동을 관찰하였다. 투약 1일째 실험군과 대조군에게 chloramphenicol 150mg/kg을...
99.

흰쥐에서 Chloramphenicol에 의해 유도된 불면에 대한 전기경련충격의 효과

추일한, 김정수, 홍승철, 한진희, 이성필 대한신경정신의학회 신경정신의학 8 Pages

대한신경정신의학회 신경정신의학 1999, 제 38권 제 5호 23 1170-1177 (8 pages)

추일한, 김정수, 홍승철, 한진희, 이성필 저
...
- 3,000원
연구목적： 인자의 하나로 밝혀진 muramyl peptide가 사람을 포함하여 여러 포유동물종에서 분리되었는데 이는 박테리 아의 세포벽을 형성하고 있는 peptidoglycans의 구성성분으로 macrophage의 작용으로 생체에서 형성되어 수 면을 유도한다고 알려져 있다. 이를 뒷받침하는 근거로는 사람과 쥐에서 항생제를 사용하면 수면이 감소한다는 연구결과가 있었으며 이는 장내 세균의 감소로 인한 결과로 생각되고 있다. 또한 전기경련충격(ECS)는 동물실 험에서 서파수면(slow wave sleep)의 증가와 역설수면(paradoxical sleep)을...
100.

自殺企圖患者에 對한 臨床的考察

劉東沫 대한신경정신의학회 신경정신의학 12 Pages

대한신경정신의학회 신경정신의학 1978, 제 17권 제 4호 3 352-363 (12 pages)

劉東沫 저
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- 4,100원

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