자료유형
발행기관
- 대한골관절종양학회(54)
- 대한수의학회(34)
- 아시아태평양암예방학회(27)
- 대한생리학회-대한약리학회(17)
- 대한신경정신의학회(4)
- 대한영상의학회(4)
- 대한구강악안면외과학회(3)
- 대한흉부외과학회(3)
- 생화학분자생물학회(3)
- 한국임상수의학회(3)
- 대한구강악안면방사선학회(2)
- 대한두경부종양학회(2)
- 대한악안면성형재건외과학회(2)
- 대한자기공명의과학회(2)
- 영남의대학술지편집위원회(2)
- 한국생명과학회(2)
- 한국생약학회(2)
- 대한구강생물학회(1)
- 대한독성유전단백체학회(1)
- 대한미생물학회(1)
- 대한방사선종양학회(1)
- 대한세포병리학회(1)
- 대한안면통증구강내과학회(1)
- 대한약리학회(1)
- 대한치과교정학회(1)
- 대한치과보존학회(1)
- 대한치과보철학회(1)
- 물리치료재활과학회(1)
- 한국가축위생학회(1)
- 한국독성학회(1)
- 한국미술치료학회(1)
- 한국분자세포생물학회(1)
- 한국수산과학회(1)
- 한국유전체학회(1)
- 한국임상약학회(1)
- 한국환경독성학회(1)
간행물
- 대한골관절종양학회지(54)
- ASIAN PACIFIC JOURNAL OF CANCER PREVENTION : APJCP(27)
- JOURNAL OF VETERINARY SCIENCE(19)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(17)
- 대한수의학회 학술대회발표집(8)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(7)
- 대한방사선의학회지(4)
- 신경정신의학(4)
- JOURNAL OF VETERINARY CLINICS(3)
- 대한구강악안면외과학회지(3)
- NATURAL PRODUCT SCIENCES(2)
- 대한 두경부 종양 학회지(2)
- 대한악안면성형재건외과학회지(2)
- 대한자기공명의과학회지(2)
- 대한흉부외과학회지(2)
- 생명과학회지(2)
- 영남의대 학술지(2)
- BMB REPORTS(1)
- EXPERIMENTAL & MOLECULAR MEDICINE : EMM(1)
- FISHERIES AND AQUATIC SCIENCES(1)
- GENOMICS & INFORMATICS(1)
- IMAGING SCIENCE IN DENTISTRY(1)
- INTERNATIONAL JOURNAL OF ORAL BIOLOGY : OFFICIAL JOURNAL OF THE KOREAN ACADEMY OF ORAL BIOLOGY AND T(1)
- JOURNAL OF BACTERIOLOGY AND VIROLOGY : JBV(1)
- JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY(1)
- JOURNAL OF TOXICOLOGY AND PUBLIC HEALTH : AN OFFICIAL JOURNAL OF THE KOREAN SOCIETY OF TOXICOLOGY(1)
- MOLECULAR & CELLULAR TOXICOLOGY(1)
- MOLECULES AND CELLS(1)
- PHYSICAL THERAPY REHABILITATION SCIENCE(1)
- THE KOREAN JOURNAL OF ORTHODONTICS(1)
- THE KOREAN JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY(1)
- 대한구강내과학회지(1)
- 대한방사선종양학회지(1)
- 대한세포병리학회지(1)
- 대한약리학잡지(1)
- 대한치과보존학회지(1)
- 대한치과보철학회지(1)
- 미술치료연구(1)
- 치과방사선(1)
- 한국가축위생학회지(1)
- 한국임상약학회지(1)
- 환경독성학회지(1)
전체 선택해제
총 185건 검색
본문검색 결과만 보기
-
Novel functional roles of caspase-related genes in the regulation of apoptosis and autophagy
Ju-HyunShin, Sang-HyunMin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 3 573-580 (8 pages)
Caspases, a family of cysteine proteases, cleave substrates and play significant roles in apoptosis, autophagy, and development. Recently, our group identified 72 genes that interact with Death Caspase-1 (DCP-1) proteins in Drosophila by genetic screening of 15,000 EP lines. However, the cellular functions and molecular mechanisms of the screened genes, such as their involvement in apoptosis and autophagy, are poorly understood in mammalian cells. In order to study the functional... -
Oleanolic acid induced autophagic cell death in hepatocellular carcinoma cells via PI3K⁄Akt⁄mTOR and ROS-dependent pathway
YangShi, QingweiSong, DianheHu, XiaohuZhuang, ShengcaiYu, DacaiTeng 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 2 237-243 (7 pages)
Oleanolic acid (OA) has a wide variety of bioactivities such as hepatoprotective, anti-inflammatory and anti-cancer activity and is used for medicinal purposes in many Asian countries. In the present study, the effect of OA on induction of autophagy in human hepatocellular carcinoma HepG2 and SMC7721 cells and the related mechanisms were investigated. MTT assay showed that OA significantly inhibited HepG2 and SMC7721 cells growth. OA treatment enhanced formation of autophagic vacuoles as... -
Polymorphisms of SLC22A9 (hOAT7) in Korean Females with Osteoporosis
SeongKyuAhn, ChangKookSuh, SeokHoCha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 3 319-325 (7 pages)
Among solute carrier proteins, the organic anion transporters (OATs) play an important role for the elimination or reabsorption of endogenous and exogenous negatively charged anionic compounds. Among OATs, SLC22A9 (hOAT7) transports estrone sulfate with high affinity. The net decrease of estrogen, especially in post-menopausal women induces rapid bone loss. The present study was performed to search the SNP within exon regions of SLC22A9 in Korean females with osteoporosis. Fifty healthy controls... -
Dieckol Attenuates Microglia-mediated Neuronal Cell Death via ERK, Akt and NADPH Oxidase-mediated Pathways
YanjiCui, Jee-YunPark, JinjiWu, JiHyungLee, Yoon-SilYang, Moon-SeokKang, Sung-CherlJung, JooMinPark, Eun-SookYoo, Seong-HoKim, SangmeeAhnJ 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 5 219-228 (10 pages)
Excessive microglial activation and subsequent neuroinflammation lead to synaptic loss and dysfunction as well as neuronal cell death, which are involved in the pathogenesis and progression of several neurodegenerative diseases. Thus, the regulation of microglial activation has been evaluated as effective therapeutic strategies. Although dieckol (DEK), one of the phlorotannins isolated from marine brown alga Ecklonia cava, has been previously reported to inhibit microglial activation, the... -
Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells
Yun-HeeBae, JongHyoRyu, Hyun-JooPark, KwangRokKim, Hee-JunWee, Ok-HeeLee, Hye-OckJang, Moon-KyoungBae, Kyu-WonKim, Soo-KyungBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 6 291-297 (7 pages)
Notch1 has been reported to be highly expressed in triple-negative and other subtypes of breast cancer. Mutant p53 (R280K) is overexpressed in MDA-MB-231 triple-negative human breast cancer cells. The present study aimed to determine whether the mutant p53 can be a potent transcriptional activator of the Notch1 in MDA-MB-231 cells, and explore the role of this mutant p53-Notch1 axis in curcumin-induced apoptosis. We found that curcumin treatment resulted in an induction of apoptosis in... -
Regulation of Ca2+ Signaling in Pulmonary Hypertension
AmyL.Firth, JunYeonWon, WonSunPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 1 1-8 (8 pages)
Understanding the cellular and molecular mechanisms involved in the development and progression of pulmonary hypertension (PH) remains imperative if we are to successfully improve the quality of life and life span of patients with the disease. A whole plethora of mechanisms are associated with the development and progression of PH. Such complexity makes it difficult to isolate one particular pathway to target clinically. Changes in intracellular free calcium concentration, the most common... -
Quercetin-induced Growth Inhibition in Human Bladder Cancer Cells Is Associated with an Increase in Ca2＋-activated K＋ Channels
YangmiKim, Wun-JaeKim, , Eun-JongCha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.5 5 279-284 (6 pages)
Quercetin (3,3',4',5,7-pentahydroxyflavone) is an attractive therapeutic flavonoid for cancer treatment because of its beneficial properties including apoptotic, antioxidant, and antiproliferative effects on cancer cells. However, the exact mechanism of action of quercetin on ion channel modulation is poorly understood in bladder cancer 253J cells. In this study, we demonstrated that large conductance Ca2＋- activated K＋ (BKCa) or MaxiK channels were functionally expressed in 253J cells, and... -
Ape1/Ref-1 Stimulates GDNF/GFRα1-mediated Downstream Signaling and Neuroblastoma Proliferation
Mi-YoungKang, KweonYoungKim, YoungYoon, YoonsungKang, HongBeumKim, ChaKyungYoun, Dong-HuiKim, Mi-HwaKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 3 349-356 (8 pages)
We previously reported that glial cell line-derived neurotropic factor (GDNF) receptor Ձ1 (GFRՁ1) is a direct target of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1). In the present study, we further analyzed the physiological roles of Ape1/Ref-1-induced GFRՁ1 expression in Neuro2a mouse neuroblastoma cells. Ape1/Ref-1 expression caused the clustering of GFRՁ1 immunoreactivity in lipid rafts in response to GDNF. We also found that Ret, a downstream target of... -
Increase of NADPH-diaphorase Expression in Hypothalamus of Stat4 Knockout Mice
MeeSookHong, JeongYoonSong, DongHwanYun, Jeong-JeCho, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 1 337-341 (5 pages)
Signal transducer and activator of transcription 4 (STAT4), a STAT family member, mediates interleukin 12 (IL12) signal transduction. IL12 is known to be related to calorie-restricted status. In the central nervous system, IL12 also enhances the production of nitric oxide (NO), which regulates food intake. In this study, the expression of neuronal NO synthase (Nos1), which is also related to food intake, was investigated in the hypothalamic areas of Stat4 knockout (KO) mice using nicotinamide... -
Involvement of ERK1/2 and JNK Pathways in 17β-estradiol Induced Kir6.2 and SK2 Upregulation in Rat Osteoblast-like Cells
Jung-WookKim, Eun-KyoungYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 6 199-206 (8 pages)
The functional expression of potassium (K) channels has electrophysiologically been studied in bone cells from several species, however, their identity and regulation of gene expressions in bone cells are not well known. In the present study, to investigate how K channel expressions are regulated by estrogen, we measured changes of transcript levels of various Ca2-activated (KCa) and ATP-sensitive K channels in rat osteoblastic ROS 17/2.8 cells after treatment with...
