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Chicken RNA-binding protein T-cell internal antigen-1 contributes to stress granule formation in chicken cells and tissues
Yingjie Sun, Pin Zhang, Hang Zheng, Luna Dong, Lei Tan, Cuiping Song, Xusheng Qiu, Ying Liao, Chunchun Meng, Shengqing Yu, Chan 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 2 3-12 (10 pages)
N-terminal green fluorescent protein (GFP) tag (pntGFP-cPRD) or Flag tag (pFlag-cPRD) induced the production of typical SGs. However, C-terminal GFP-tagged cPRD induced notably large cytoplasmic granules that were devoid of endogenous G3BP1 and remained stable when exposed to cycloheximide, indicating that these were not typical SGs, and that the pntGFP tag influences cPRD localization. Finally, endogenous cTIA-1 was recruited to SGs in chicken cells and tissues under environmental stress. Taken... -
Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B
KyuPilLee, HyunJinKim, DongkiYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 10 91-99 (9 pages)
Protein phosphatase 1 (PP1) is involved in various signal transduction mechanisms as an extensive regulator. The PP1 catalytic subunit (PP1c) recognizes and binds to PP1-binding consensus residues (FxxR/KxR/K) in NBCe1-B. Consequently, we focused on identifying the function of the PP1-binding consensus residue, 922FMDRLK927, in NBCe1-B. Using site-directed mutagenesis and co-immunoprecipitation assays, we revealed that in cases where the residues were substituted (F922A, R925A, and K927A) or... -
Role of Nucleotide-binding and Oligomerization Domain 2 Protein (NOD2) in the Development of Atherosclerosis
Ha-JeongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.6 1 479-484 (6 pages)
NOD2 (nucleotide-binding and oligomerization domain 2) was initially reported as a susceptibility gene for Crohn’s disease, with several studies focused on elucidating its molecular mechanism in the progression of Crohn’s disease. We now know that NOD2 is an intracellular bacterial sensing receptor, and that MDP-mediated NOD2 activation drives inflammatory signaling. Various mutations in NOD2 have been reported, with NOD2 loss of function being associated with the development of Crohn’s... -
Research Notes : Identification of the Capsid Protein-binding Region of the SL1(+) RNA Located at the 5` Region of the Potato virus X Genome
한국식물병리학회 The Plant Pathology Journal 6 Pages
한국식물병리학회 The Plant Pathology Journal 2012, 28권 1호 10 75-80 (6 pages)
We also conducted EMSA and yeast three-hybrid analyses with RNAs containing various mutations of SL1(+) RNA elements. These analyses indicated that SL1(+) RNA is required for the interaction with PVX CP and that the RNA sequences located at the loop C and tetra loop of the SL1(+) are crucial for CP binding. These results indicate that, in addition to being important for RNA accumulation, the SL1(+) RNA from the 5` region of the PVX genome is also required for specific binding of PVX CP. -
한우 CCAAT/enhancer-binding protein α(C/EBPα) 유전자의 동정과 mRNA의 발현
정영희, 이상미, 박효영, 윤두학, 문승주, 정의룡, 강만종, Jeoung. Y.H., Lee. S.M., Park. H.Y., Yoon. D.H., Moon. S.J., Chung. E.R., Kang. M.J. 한국동물자원과학회 한국동물자원과학회지 8 Pages
한국동물자원과학회 한국동물자원과학회지 2004, Vol.46 No.6 909-916 (8 pages)
CCAAT/enhancer binding protein(C/EBP)는 지방전구세포의 분화과정에서 말현하는 전사인자군에 속한다. 이러한 C/EBP 중에서 C/EBP $alpha$ 는 지방세포의 분화와 지방침착에 있어 중요한 역할을 수행허는 것으로 알려져 있다. 본 연구에서는 한우 C/EBP$alpha$ 유전자를 분리 동정하고 그 발현을 조사하였다. 한우 C/EBP$alpha$ 유전자는 1059bp의 open reading frame으로 구성되어 있으며 353개의 아미노산을 암호화하고 있었다. 그리고 한우 C/EBP $alpha$ 아미노산을 다른 종과 비교하였을 때 매우 높은 상동성을 나타내었다.... -
Protection of Metal Stress in Saccharomyces cerevisiae: Cadmium Tolerance Requies the Presence if Two ATP-Binding Domains of Hsp 104 Protein
이경희, 엄정훈, Lee. Gyeong Hui, Eom. Jeong Hun 대한화학회 Bulletin of the Korean Chemical Society 5 Pages
대한화학회 Bulletin of the Korean Chemical Society 2001, Vol.22 No.5 514-518 (5 pages)
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생리학 : MCF-7 cell에서 all-trans retinoic acid에 의한 insulin-Like growth factor-I와 insulin-Like growth factor binding protein-3 분비조절에 있어서 PKC-δ의 역할
이선미, 김상훈, 최광수 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 9 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2006, 제 46권 제 2호 2 97-105 (9 pages)
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Regulation of Phosphorylated cAMP Response Element-Binding Protein, Fos-Related Antigen and FosB Expression by Dopamine Agonists in Rat Striatum
EunSangChoeJongYeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.4 2 299-305 (7 pages)
the agonist, phosphorylated cAMP response element-binding protein (pCREB), Fos-related antigens (FRA) and FosB immunoreactivity (IR) was compared at 20 and 120 min time points in the selected areas of the striatum. Semi-quantitative immunocytochemistry showed that amphetamine (5 mg/kg, i.p.) significantly increased pCREB-IR at 20 min, sustained up to 60 min and decreased at 120 min after the infusion. Like amphetamine, the full D1 agonist, SKF82958 (0.5 mg/kg, s.c.), also increased pCREB-IR at... -
Molecular Cloning and Characterization of Chymotrypsin Inhibitor and Chitin-Binding Protein Homologs from the Bumblebee Bombus terrestris
Qiu. Yuling, Yoon. Hyung-Joo, Jin. Byung-Rae 한국잠사학회 International journal of industrial entomology 7 Pages
한국잠사학회 International journal of industrial entomology 2012, Vol.25 No.1 115-121 (7 pages)


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