학지사 뉴논문

총 11,987건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

10051.

Effects of Exogenous ATP on Calcium Mobilization and Cell Proliferation in C6 Glioma Cell

Eun-JungLee, SeokHoCha, WoonKyuLee, Kweon-HaengLee, Sang-BokLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 3 419-425 (7 pages)

Eun-JungLee, SeokHoCha, WoonKyuLee, Kweon-HaengLee, Sang-BokLee 저
...
- 3,000원
To clarify the effect of extracellular ATP in cultured C6 glioma cells, ATP-induced cytosolic free calcium ([Ca2⁢]i) mobilization and cell proliferation were investigated. ATP-induced [Ca2⁢]i increased in a dose-dependent manner (10⁣7 M∼10⁣3 M). ATP-induced [Ca2⁢]i increases were slightly slowed in extracellular calcium-free conditions especially in sustained phase. ATP-induced [Ca2⁢]i increment was also inhibited by the pretreatment of U73122, a...
10052.

Tetrachloroauric Acid Depresses the Activation Processes of Phagocytic Cells

ChungSooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 13 377-384 (8 pages)

ChungSooLee 저
...
- 3,000원
Gold compounds depress phagocytic cell responses, including chemotaxis, and respiratory burst. However, the effects of gold compounds on the function of phagocytic cells are variable according to the preparation of medicine. In this study, effect of tetrachloroauric acid on activated neutrophil responses, including respiratory burst, lysosomal enzyme release and change of intracellular Ca2+ level and on the synthesis of interleukin-8 and granulocyte-macrophage colony stimulating factor by...
10053.

Effects of Glutamate Receptor Antagonists and Protein Synthesis Inhibitor on Delayed Neuronal Death Induced by Transient Global Ischemia in Rat Brain

JunSeogKo, ChoonSangBae, Jong-KeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 2 279-286 (8 pages)

JunSeogKo, ChoonSangBae, Jong-KeunKim 저
...
- 3,000원
It has been well documented that transient forebrain global ischemia causes selective neuronal degeneration in hippocampal CA1 pyramidal neurons with a delay of a few days. The mechanism of this delayed hippocampal CA1 pyramidal neuronal death (DND) is still controversial. To delineate the mechanisms of the DND, the effects of treatment with MK-801, an NMDA receptor antagonist, kynurenic acid, a NMDA/non-NMDA receptor antagonist, and/or cycloheximide, a protein synthesis inhibitor, on the DND...
10054.

Inhibitory Effects of Ginseng Saponins on c-fos mRNA Expression and the Proliferation of Rat Aortic Vascular Smooth Muscle Cells Stimulated by Angiotensin II

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 8 201-207 (7 pages)

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 저
...
- 3,000원
To evaluate the possibility that the ginseng saponins could be developed as an anti-arteriosclerotic agent, we examined the inhibitory effects of ginseng saponins (total saponin[TS], panaxatriol[PT], panaxadiol[PD]) on the expression of c-fos mRNA and the proliferation of cultured rat aortic vascular smooth muscle cells (VSMCs) stimulated by angiotensin II (Ang II). TS and PT (1.0 mg/ml) suppressed c-fos mRNA induction in VSMCs stimulated by 10-5 M Ang II. The order of inhibitory potency was...
10055.

비-혈관평활근에서 새로운 K+ 동로 개방제인 SKP-450의 약리 학적 작용의 특성 -Levcromakalim의 작용과 비 교

홍기환, 박지영, 김현희, 유성은 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 17 759-767 (9 pages)

홍기환, 박지영, 김현희, 유성은 저
...
- 3,000원
Medicine， Pusan National University， Pusan， 602-739; and 2Korea Research Institute of Chemical Technology， Daejeon， Korea In the present study， we characterized the non-vascu1ar smooth musc1e relaxant effects of a novel benzoyran derivative， SKP-450 (2- [2" (1" ，3" -dioxolone)-2-methyl-4-(2’ -oxo-l ’ -pyrrolidinyl)-6-띠tro-2H-l- benzopyran) and its metabolite， SKP-31O， in comparison with levcromakalim (LCRK). In the rat stomach fundus， the spontaneous 6.5 motility stimulated by 10...
10056.

Regulatory Mechanisms of Angiotensin II on the Na+/H+ Antiport System in Rabbit Renal Proximal Tubule Cells. I. Stimulatory Effects of ANG II on Na+ Uptake

HoJaeHan, HyunJuKoh, SooHyunPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 8 413-423 (11 pages)

HoJaeHan, HyunJuKoh, SooHyunPark 저
...
- 4,000원
The importance of the kidney in the development of hypertension was first demonstrated by Goldblatt and his colleagues more than fifty years ago. Many hormones and other regulatory factors have been proposed to play a major role in the development of hypertension. Among these factors angiotensin II (ANG II) is closely involved in renal hypertension development since it directly regulates Na+ reabsorption in the renal proximal tubule. Thus the aim of the present study was to examine signaling...
10057.

Mechanisms Underlying Relaxations Caused by Angiotensin II and Its Analogs in Isolated Rabbit Mesenteric Artery

KiWhanHong, , JiYoungPark, ChiDaeKim, WonSukLee, ByungYongRhim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 6 393-402 (10 pages)

KiWhanHong, , JiYoungPark, ChiDaeKim, WonSukLee, ByungYongRhim 저
...
- 3,000원
In the present study, we characterized the angiotensin II (AII)-induced relaxations in the phenylephrine- precontracted rabbit mesenteric arteries with endothelium. 1) AII-induced relaxation was consistently observed in the rabbit mesenteric arteries with and without endothelium, but not in the aortic segment with endothelium. 2) AII-induced endothelium-dependent relaxation was markedly inhibited by Nw-nitro- L-arginine (L-NNA, 100 ㄍM), methylene blue (10 ㄍM) and LY83583 (10...
10058.

흰쥐 해마에서 Norepinephrine 유리에 미치는 N6-cyclopentyladenosine 및 Forskolin의 영향 Interaction of Forskolin with the Effect of N6-cyclopentyladenosine on Norepinephrine Release in Rat Hippocampus

최봉규, 김도경, 손용, 양의종, BongKyuChoi, DoKyungKim, YongSon, UeJongYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 1 225-231 (7 pages)

최봉규, 김도경, 손용, 양의종, BongKyuChoi, DoKyungKim, YongSon, UeJongYang 저
...
- 3,000원
As it has been reported that the depolarization-induced norepinephrine (NE) release is modulated by activation of presynaptic A1-adenosine heteroreceptor and various lines of evidence indicate the involvement of adenylate cyclase system in A1-adenosine post-receptor mechanism in hippocampus, it was attempted to delineate the role of adenylate cyclase system in the A1-receptor-mediated control of NE release in this study. Slices from rat hippocampus were equilibrated with [3H]-NE and the release...
10059.

Lithium-induced Increase of Synaptosomal Uptake of Norepinephrine in Rat Brain

Young-WukCho, Seung-HoHan, Chang-JuKim, Byung-IlMin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 2 127-133 (7 pages)

Young-WukCho, Seung-HoHan, Chang-JuKim, Byung-IlMin 저
...
- 3,000원
Lithium remains the most widely used therapeutic agent for bipolar affective disorder, particularly mania. Although many investigators have studied the effects of lithium on abnormalities in monoamine neurotransmitter as a pathophysiological basis of affective disorder, the action mechanism of lithium ion remains still unknown. To explore the action mechanism of lithium in the brain, we examined the effects of lithium on the extrasynaptosomal concentrations of catecholamines and their...
10060.

Regulation of Adenosine Receptors in Rat Brain following Chronic Carbamazepine Treatment

KyungSunPark, WanSukYang, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 2 13-17 (5 pages)

KyungSunPark, WanSukYang, KyungHwanKim 저
...
- 1,500원
Carbamazepine (CBZ), an anticonvulsant, has beeen reported to displace ligands at adenosine receptors. Several studies have demonstrated that as far as A2 adenosine receptors is concerned, CBZ acts as an antagonist. However, the situation with regard to A1 receptors is less straightforward. In this study, we describe the effects of one-week CBZ treatment (25 mg/kg/day) on cerebrocortical A1 adenosine receptors. A1 adenosine receptor bindings as determined by using [3H]DPCPX was not...

한주간 이슈검색어