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1041.

Spontaneous Electrical Activity in Cerebellar Purkinje Neurons of Postnatal Rats

SangChaeNam 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 2 355-366 (12 pages)

SangChaeNam 저
...
- 4,100원
Although cerebellar Purkinje cells display spontaneous electrical activity in vivo and in slice experiments, the mechanism of the spontaneous activity generation has not been clearly understood. The aim of this study was to investigate whether cerebellar Purkinje cells of postnatal rats generate spontaneous electrical activity without synaptic inputs. Dissociated cerebellar Purkinje cells were used for reducing synaptic inputs in the present study. Cerebellar Purkinje cells with dendrites were...
1042.

Reduction of TNFα-induced Oxidative DNA Damage Product, 8-Hydroxy-2′-Deoxyguanosine, in L929 Cells Stably Transfected with Small Heat Shock Protein

Young-MeePark, Eun-MiChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 11 209-219 (11 pages)

Young-MeePark, Eun-MiChoi 저
...
- 4,000원
Previous studies have demonstrated that oxidative stress involving generation of reactive oxygen species (ROS) is responsible for the cytotoxic action of TNFα. Protective effect of small heat shock proteins (small HSP) against diverse oxidative stress conditions has been suggeted. Although overexpression of small hsp was shown to provide an enhanced survival of TNFα-sensitive cells when challenged with TNFα, neither the nature of TNFα-induced cytotoxicity nor the protective mechanism of...
1043.

Functional Characteristics of Neutral Amino Acid Transporter in Opossum Kidney (OK) Cells

JaeSukWoo, MoonHwanPark, SaeOkOh, JinSupJung, YongKeunKim, SangHoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 8 185-193 (9 pages)

JaeSukWoo, MoonHwanPark, SaeOkOh, JinSupJung, YongKeunKim, SangHoLee 저
...
- 3,000원
The characteristics of Na+-dependent cycloleucine uptake was investigated in OK cells with regard to substrate specificity and regulation by protein kinase C (PKC). Inhibition studies with different synthetic and natural amino acids showed a broad spectrum affinity to neutral amino acids regardless of their different side chains including branched or aromatic, indicating that the Na+-dependent cycloleucine uptake in OK cells is mediated by System Bo or System Bo-like transporter rather than the...
1044.

Two Types of Voltage-dependent Outward Potassium Currents in Smooth Muscle Cells of Rabbit Basilar Atery

TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 15 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 7 169-183 (15 pages)

TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 저
...
- 4,400원
We have investigated the two types of voltage-dependent outward potassium (K) currents, i.e. delayed rectifier K current (IK(V)) and 'A-like' transient outward K current (Ito) with patch-clamp technique in single smooth muscle cells (SMCs) isolated from rabbit basilar artery, and investigated the characteristics of them. The time-courses of activation were well fitted by exponential function raised to second power (n2) in IK(v) and fourth power (n4) in Ito. The activation, inactivation and...
1045.

Neural Adaptation of Beta Adrenergic Receptor Subtypes after Chronic Imipramine Treatment A Quantitative Autoradiographic Study

Hae-YoungPark, Young-SookHong, Chan-WoongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 6 161-167 (7 pages)

Hae-YoungPark, Young-SookHong, Chan-WoongPark 저
...
- 3,000원
This study compares the subtypes of central beta adrenergic receptors (ARs) of brains of untreated rats with those of imipramine-treated rats. Beta adrenergic receptors were measured by quantitative autoradiography of the binding of 3H-dihydroalprenolol (3H-DHA) in coronal sections of rat brain. Repeated treatment of rats with imipramine significantly reduced the binding of 3H-DHA to beta-1 AR in many brain areas, especially throughout the cerebral cortex, hippocampus, thalamus, and amygdala....
1046.

[3H]MK-801 Binding to the Synaptic Membranes of Rat Forebrains Age-related Regulation by Glutamate, Glycine and Spermine

JungsookCho, JaeYangKong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 1 117-125 (9 pages)

JungsookCho, JaeYangKong 저
...
- 3,000원
The N-methyl-D-aspartate (NMDA) receptor-mediated glutamatergic neurotransmission is involved in synaptic plasticity, developmental processes, learning and memory and many neuropathological disorders including age-related diseases. In the present study, regulation of the NMDA receptor properties by various ligands was investigated using [3H]MK-801 binding studies in the synaptic membranes of young and aged rat forebrains. The binding in the presence of glutamate and glycine increased...
1047.

Regulation of Adenosine Receptors in Rat Brain following Chronic Carbamazepine Treatment

KyungSunPark, WanSukYang, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 2 13-17 (5 pages)

KyungSunPark, WanSukYang, KyungHwanKim 저
...
- 1,500원
Carbamazepine (CBZ), an anticonvulsant, has beeen reported to displace ligands at adenosine receptors. Several studies have demonstrated that as far as A2 adenosine receptors is concerned, CBZ acts as an antagonist. However, the situation with regard to A1 receptors is less straightforward. In this study, we describe the effects of one-week CBZ treatment (25 mg/kg/day) on cerebrocortical A1 adenosine receptors. A1 adenosine receptor bindings as determined by using [3H]DPCPX was not...
1048.

The Role of Adenosine Receptors on Acetylcholine Release in the Rat Striatum

DoKyungKim, HyeonAKim, BongKyuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 1 1-12 (12 pages)

DoKyungKim, HyeonAKim, BongKyuChoi 저
...
- 4,100원
a specific A2 adenosine receptor antagonist. 2-P-(2-carboxyethyl)phenethylamimo-5'-N-ethylcarboxamidoadenosine hydrochloride (CGS-21680C), in concentrations ranging from 0.01 to 10 ㄍM, a recently introduced potent A2 adenosine receptor agonist, increased the [3H]ACh release in a dose related fashion without changing the basal rate of release. These effects were completely abolished by DMPX (10 ㄍM). In autoradiography experiments, [3H]2-chloro-N6-cyclopentyladenosine ([3H]CCPA)...
1049.

Predicting Working Memory Capacity in Older Subjects Using Quantitative Electroencephalography

Jae Hyuk Shin, Kyungun Jhung, Jae Seok Heo, Suk Kyoon An, Jin Young Park 대한신경정신의학회 Psychiatry Investigation 6 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 7 790-795 (6 pages)

Jae Hyuk Shin, Kyungun Jhung, Jae Seok Heo, Suk Kyoon An, Jin Young Park 저
...
- 3,000원
Objective_We utilized a spectral and network analysis technique with an integrated support vector classification algorithm for the automated detection of cognitive capacity using resting state electroencephalogram (EEG) signals. Methods_An eyes-closed resting EEG was recorded in 158 older subjects, and spectral EEG parameters in seven frequency bands, as well as functional brain network parameters were, calculated. In the feature extraction stage, the statistical power of the spectral and...
1050.

The Staging of Major Mood Disorders

Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)

Ather Muneer, Rana Mazommil 저
...
- 4,100원
Objective_Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods_In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like “major depressive disorder and staging,” “bipolar disorder and neuroprogression,” etc. To incorporate the latest findings the search was limited to the last 10 years. Both original and review articles were...

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