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화재시 터널내 열유동 시뮬레이션 모델 연구
우경범, 김원갑, 한화택 대한설비공학회 설비공학논문집 8 Pages
대한설비공학회 설비공학논문집 2002, Vol.14 No.7 584-591 (8 pages)
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실내공간에서 화재 발생위치에 따른 연기거동에 대한 실험연구
유홍선, 정진용, 이재하, 홍기배, Yu. Hong-Seon, Jeong. Jin-Yong, Lee. Jae-Ha, Hong. Gi-Bae 대한기계학회 大韓機械學會論文集. Transactions of the Korean society of mechanical engineers. B. B 7 Pages
대한기계학회 大韓機械學會論文集. Transactions of the Korean society of mechanical engineers. B. B 2002, Vol.26 No.5 703-709 (7 pages)
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고온을 받은 초고강도 콘크리트의 역학적 특성에 관한 골재의 영향
김영선, 최형길, 대궁희문, 김규용, Kim. Young-Sun, Choi. Hyoung-Gil, Ohmiya. Yoshifumi, Kim. Gyu-Yong 한국콘크리트학회 콘크리트학회논문집 10 Pages
한국콘크리트학회 콘크리트학회논문집 2011, Vol.23 No.4 431-440 (10 pages)
콘크리트 구조물은 화재에 노출시 고온에 의해 내부 구조가 변화하며 보유하고 있는 강도와 변형 성능이 저하되어 최종적으로 수명이 단축하게 된다. 그 성능 저하 수준은 도달된 온도, 고온에 노출된 시간, 콘크리트의 배합, 골재의 특성 및 콘크리트 자체의 특성 등에 의해 결정된다. 이 연구는 물시멘트비, 잔골재율 및 굵은 골재의 최대 크기등의 변수에 대한 초고강도 콘크리트의 열적 거동을 평가하기 위해 실시되었다. 상온 및 $500^{circ}C$의 온도에 대하여 초음파 속도, 동탄성 계수, 정탄성 계수 및 압축강도 시험은... -
Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen
Yoot Mo Lee, Min Jae Seong, Jae Woong Lee, Yong Kyung Lee, Tae Myoung Kim, Sang-Yoon Nam, Dae Joong Kim, Young Won Yun, Tae Seon 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 5 27-38 (12 pages)
Bisphenol A (BPA), a ubiquitous environmental contaminant, has been shown to cause developmental toxicity and carcinogenic effects. BPA may have physiological activity through estrogen receptor (ER) -α and -β, which are expressed in the central nervous system. We previously found that exposure of BPA to immature mice resulted in behavioral alternation, suggesting that overexposure of BPA could be neurotoxic. In this study, we further investigated the molecular neurotoxic mechanisms of BPA. BPA... -
A Carbohydrate Fraction, AIP1, from Artemisia Iwayomogi Reduces the Action Potential Duration by Activation of Rapidly Activating Delayed Rectifier K+ Channels in Rabbit Ventricular Myocytes
WonSunPark, YounKyoungSon, EunAKo, SeongWooChoi, NariKim, Tae-HoonChoi, HyunJooYoun, Su-HyunJo, DaHyeHong, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 1 119-125 (7 pages)
We investigated the effects of a hot-water extract of Artemisia iwayomogi, a plant belonging to family Compositae, on cardiac ventricular delayed rectifier K+ current (IK) using the patch clamp technique. The carbohydrate fraction AIP1 dose-dependently increased the heart rate with an apparent EC50 value of 56.1±5.5Ռg/ml. Application of AIP1 reduced the action potential duration (APD) in concentration-dependent fashion by activating IK without significantly altering the resting membrane... -
Protein Kinase C Activates ATP-sensitive Potassium Channels in Rabbit Ventricular Myocytes
NariKim, JaeBoumYoum, HyunJoo, HyungkyuKim, EuiyongKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.4 1 187-194 (8 pages)
Several signal transduction pathways have been implicated in ischemic preconditioning induced by the activation of ATP-sensitive K (KATP) channels. We examined whether protein kinase C (PKC) modulated the activity of KATP channels by recording KATP channel currents in rabbit ventricular myocytes using patch-clamp technique and found that phorbol 12,13-didecanoate (PDD) enhanced pinacidil-induced KATP channel activity in the cell-attached configuration; and this effect was prevented by... -
Characterization of Acetylcholine-induced Currents in Male Rat Pelvic Ganglion Neurons
Joong-HyunPark, Kyu-SangPark, Seung-KyuCha, Keon-IlLee, Min-JungKim, Jong-YeonPark, InDeokKong, Joong-WooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 8 219-226 (8 pages)
The pelvic ganglia provide autonomic innervations to the various urogenital organs, such as the urinary bladder, prostate, and penis. It is well established that both sympathetic and parasympathetic synaptic transmissions in autonomic ganglia are mediated mainly by acetylcholine (ACh). Until now, however, the properties of ACh-induced currents and its receptors in pelvic ganglia have not clearly been elucidated. In the present study, biophysical characteristics and molecular nature of nicotinic... -
Modulation of Inwardly Rectifying K+ Channel by Intracellular and Extracellular pH in Bovine Aortic Endothelial Cells
Kyu-SangPark, InDeokKong, JoongWooLee, HyewhonRhim, YoungChulKim, InsukSo, KiWhanKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.5 4 255-260 (6 pages)
The effects of intracellular and extracellular pH on the inwardly rectifying K (IRK) channel of the bovine aortic endothelial cells (BAECs) were examined using whole-cell patch-clamp technique. The IRK current, efficiently blocked by Ba2 (200μM), is the most prominent membrane current in BAECs, which mainly determines the resting membrane potential. The expression of Kir2.1 was observed in BAECs using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis.... -
Distribution, Content and Molecular Heterogeneity of Gastrin- Releasing Peptide in Rat Pancreas
HyungSeoParkHyoungJinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 7 427-432 (6 pages)
Although importance of intrapancreatic neurons containing gastrin-releasing peptide (GRP) in control of exocrine secretion has been raised, the nature of GRP in the pancreas is unclear. Thus, the present study was undertaken to see distribution, content and molecular heterogeneity of immunoreactive GRP in the rat pancreas. Content of immunoreactive GRP in the rat pancreas was 2.99 ⁑ 0.66 ng/g wet tissues determined by radioimmunoassay. Immunoreactive GRP was most abundantly expressed in... -
External pH Effects on Delayed Rectifier K+ Currents of Small Dorsal Root Ganglion Neuron of Rat
YoungHoKim, JungHyunHahn, InJaLim, SungkwonChung, HyoWeonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 4 165-172 (8 pages)
Under certain pathophysiological conditions, such as inflammation and ischemia, the concentration of H+ ion in the tissue surrounding neurons is changed. Variations in H+ concentration are known to alter the conduction and/of the gating properties of several types of ion channels. Several types of K+ channels are modulated by pH. In this study, the whole cell configuration of the patch clamp technique has been applied to the recording of the responses of change of external pH on the delayed...


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