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101.

Role of Ca2+ in the Stimulation of Glucose Transport by Insulin in Adipocytes

Sung-HoeChang, YeonJinJang, Kun-KooPark, GhiSuKim, HeeJeongRyu, ChunSikPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 14 357-364 (8 pages)

Sung-HoeChang, YeonJinJang, Kun-KooPark, GhiSuKim, HeeJeongRyu, ChunSikPark 저
...
- 3,000원
We investigated the role of Ca2⁢ and protein kinases/phosphatases in the stimulatory effect of insulin on glucose transport. In isolated rat adipocytes, the simple omission of CaCl2 from the incubation medium significantly reduced, but did not abolish, insulin-stimulated 2-deoxy glucose (2-DG) uptake. Pre-loading adipocytes with intracellular Ca2⁢ chelator, 5,5'-dimethyl bis (o-aminophenoxy)ethane-N,N,N'N' tetraacetic acetoxymethyl ester (5,5'-dimethyl BAPTA/AM) completely blocked...
102.

Effects of Cl⁣ Channel Blockers on the Cardiac ATP-sensitive K+ Channel

Yong-GeunKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 8 305-313 (9 pages)

Yong-GeunKwak 저
...
- 3,000원
To explore whether Cl⁣ channel blockers interact with the ATP-sensitive K⁢ (KATP) channel, I have examined the effect of two common Cl⁣ channel blockers on the KATP channel activity in isolated rat ventricular myocytes using patch clamp techniques. In inside-out patches, 4,4'-diisothio-cyanatostilbene- 2,2'-disulfonic acid (DIDS) and niflumic acid applied to bath solution inhibited the KATP channel activity in a concentration-dependent manner with IC50 of 0.24 and 927μM,...
103.

Thyroid Hormone-Induced Alterations of Ca2+-ATPase and Phospholamban Protein Expression in Cardiac Sarcoplasmic Reticulum

HaeWonKim, KyungMinNoh, MiyoungPark, HeeRanLee, EunHeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 13 223-230 (8 pages)

HaeWonKim, KyungMinNoh, MiyoungPark, HeeRanLee, EunHeeLee 저
...
- 3,000원
Alterations of cardiovascular function associated with various thyroid states have been studied. In hyperthyroidism left ventricular contractility and relaxation velocity were increased, whereas these parameters were decreased in hypothyroidism. The mechanisms for these changes have been suggested to include alterations in the expression and/or activity levels of various proteins; α-myosin heavy chain, β- myosin heavy chain, β-receptors, the guanine nucleotide-binding regulatory protein, and...
104.

The Effects of Sera from Amyotrophic Lateral Sclerosis Patients on Neuromuscular Transmission and Calcium Channels in Mice

HaiDunYan, JimokKim, SungJunJung, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 17 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 13 101-117 (17 pages)

HaiDunYan, JimokKim, SungJunJung, JunKim 저
...
- 4,600원
Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease of unknown etiology in which the upper and lower motor neurons are progressively destroyed. Recent evidences support the role of autoimmune mechanisms in the pathogenesis of ALS. This study investigated the effects of sera from ALS patients on neuromuscular transmission in phrenic nerve-hemidiaphragm preparations and on calcium currents of single isolated dorsal root ganglion (DRG) cells in mice. Mice were injected with...
105.

Mechanism of Membrane Hyperpolarization by Extracellular K+ in Resistance-sized Cerebral Arterial Muscle Cell of Rabbit

SeHoonKim, KunMooChoi, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 1 1-10 (10 pages)

SeHoonKim, KunMooChoi, HoeSukKim, ByeongHwaJeon, SeokJongChang 저
...
- 3,000원
We sought to find out the mechanism of vascular relaxation by extracellular K⁢ concentration ([K⁢]o) in the cerebral resistant arteriole from rabbit. Single cells were isolated from the cerebral resistant arteriole, and using voltage-clamp technique barium-sensitive K⁢ currents were recorded, and their characteristics were observed. Afterwards, the changes in membrane potential and currents through the membrane caused by the change in [K⁢]o was observed. In the smooth...
106.

Decrease in Ca2+ Storage in the Cardiac Sarcoplasmic Reticulum of Diabetic Rat

Won-TaeKim, HaeWonKim, Young-KeeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 9 725-732 (8 pages)

Won-TaeKim, HaeWonKim, Young-KeeKim 저
...
- 3,000원
In order to elucidate the molecular mechanism of the intracellular Ca2⁢ overload frequently reported from diabetic heart, diabetic rats were induced by the administration of streptozotocin, the membrane vesicles of junctional SR (heavy SR, HSR) were isolated from the ventricular myocytes, and SR Ca2⁢ uptake and SR Ca2⁢ release were measured. The activity of SR Ca2⁢-ATPase was 562⁑14 nmol/min/mg protein in control heart. The activity was decreased to 413⁑30...
107.

Increased Activity of Large Conductance Ca2+-Activated K+ Channels in Negatively-Charged Lipid Membranes

JinBongParkPanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 15 529-539 (11 pages)

JinBongParkPanDongRyu 저
...
- 4,000원
The effects of membrane surface charge originated from lipid head groups on ion channels were tested by analyzing the activity of single large conductance Ca2⁢-activated K⁢ (maxi K) channel from rat skeletal muscle. The conductances and open-state probability (Po) of single maxi K channels were compared in three types of planar lipid bilayers formed from a neutral phosphatidylethanolamine (PE) or two negatively-charged phospholipids, phosphatidylserine (PS) and phosphatidylinositol...
108.

Mechanism of Vasoactive Intestinal Polypeptide-Induced Catecholamine Secretion from the Rat Adrenal Medulla

Dong-YoonLim, Jae-BongHeo, Cheol-HeeChoi, Geon-HanLim, Yong-GyoonLee, Song-HoonOh, Il-SikKim, Jong-InKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 6 443-454 (12 pages)

Dong-YoonLim, Jae-BongHeo, Cheol-HeeChoi, Geon-HanLim, Yong-GyoonLee, Song-HoonOh, Il-SikKim, Jong-InKim 저
...
- 4,100원
(5.6⁓10⁣2 M) were potentiated by infusion of VIP (3⁓10⁣6M for 5 min). Taken together, these experimental results indicate that VIP causes CA release in a fashion of calcium ion -dependence, suggesting strongly that there exists a noncholinergic mechanism that may be involved in the regulation of adrenomedullary CA secretion through VIP receptors in the rat adrenal gland, and that VIP may be the noncholinergic excitatory secretagogue present in the chromaffin cells.
109.

Characteristic Intracelluar Response to Lidocaine And MK-801 of Hippocampal Neurons An In Vivo Intracellular Neuron Recording Study

Byung-JuChoiJin-HwaCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 4 297-305 (9 pages)

Byung-JuChoiJin-HwaCho 저
...
- 3,000원
an average discharge rate of 0.6⁑0.4 Hz. Upon depolarization of the membrane by 0.8 nA for 400 ms, all of the tested cells exhibited accommodation of spike discharge. The most common synaptic response contained an EPSP followed by early-IPSP and late-IPSP. Analysis of the voltage dependence revealed that the early-IPSP and late-IPSP were putative Cl⁣-and K⁢-dependent, respectively. Systemic injection of the NMDA receptor blocker, MK-801, did not block synaptic responses to the...
110.

Ca2+ Signalling in Endothelial Cells Role of Ion Channels

BerndNilius, FelixViana, MasahiroKamouchi, CristinaFasolato, JanEggermont, GuyDroogmans 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 1 133-145 (13 pages)

BerndNilius, FelixViana, MasahiroKamouchi, CristinaFasolato, JanEggermont, GuyDroogmans 저
...
- 4,200원

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