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1121.

Cytochrome P450 2E1 Activity in a Korean Population

Dou-HyunMuhn, Ji-MinChae, Jae-YongBahn, Hae-JungSong, Hyung-KeeKim, Jun-TackKwon, Dong-RyulSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 16 597-602 (6 pages)

Dou-HyunMuhn, Ji-MinChae, Jae-YongBahn, Hae-JungSong, Hyung-KeeKim, Jun-TackKwon, Dong-RyulSohn 저
...
- 3,000원
Cytochrome P450 2E1 (CYP2E1) is involved in the toxicity and carcinogenicity of a number of solvents and xenobiotics. Like the various types of oxidation pharmacogenetics, the activity of the enzyme shows a discernible interindividual and interethnic variation. However, no pharmacogenetic information on CYP2E1 polymorphism has been available from a Korean population. The aim of this study was to explore the pharmacogenetics of CYP2E1 polymorphism in a native Koreans after an oral 400 mg dose of...
1122.

Effects of Ginsenosides on the Mechanism of Histamine Release in the Guinea Pig Lung Mast Cells Activated by Specific Antigen- Antibody Reactions

JaiYoulRo, YoungSooAhn, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 11 445-456 (12 pages)

JaiYoulRo, YoungSooAhn, KyungHwanKim 저
...
- 4,100원
We previously reported that some components of ginsenosides decreased mediator releases evoked by the activation of mast cells with specific antigen-antibody reactions. This study aimed to assess the effects of ginsenosides (Rb2, Re) on the mechanism of histamine release in the mast cell activation. We partially purified guinea pig lung mast cells by using enzyme digestion, the rough and the discontinuous percoll density gradient method. Mast cells were sensitized with IgG1 and challenged with...
1123.

Effect of Hemorrhage on mRNA Expressions of Renin, Angiotensinogen and AT1 Receptors in Rat Central and Peripheral Tissues

MiKyungLee, HakryulJo, Kyung-SoonKim, Eun-KyoungYang, Won-JungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 5 151-159 (9 pages)

MiKyungLee, HakryulJo, Kyung-SoonKim, Eun-KyoungYang, Won-JungLee 저
...
- 3,000원
In an attempt to investigate whether hemorrhage affects the gene expression of the renin-angioteusin system (RAS) components in the brain and peripheral angiotensin-generating tissues, changes in mRNA levels of the RAS components in response to hemorrhage were measured in conscious unrestrained rats. Wistar rats were bled at a rate of 3 ml/kg/min for 5 min, and then decapitated 7 h after hemorrhage. Levels of mRNA for renin, angiotensinogen and angiotensin II-AT1 receptor subtypes (AT1A and...
1124.

[3H]MK-801 Binding to the Synaptic Membranes of Rat Forebrains Age-related Regulation by Glutamate, Glycine and Spermine

JungsookCho, JaeYangKong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 1 117-125 (9 pages)

JungsookCho, JaeYangKong 저
...
- 3,000원
The N-methyl-D-aspartate (NMDA) receptor-mediated glutamatergic neurotransmission is involved in synaptic plasticity, developmental processes, learning and memory and many neuropathological disorders including age-related diseases. In the present study, regulation of the NMDA receptor properties by various ligands was investigated using [3H]MK-801 binding studies in the synaptic membranes of young and aged rat forebrains. The binding in the presence of glutamate and glycine increased...
1125.

Gene Expression of Intrarenal Renin-angiotensin System in Streptozotocin-induced Diabetic Rats

EunKyoungYang, InKyeomKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 6 45-53 (9 pages)

EunKyoungYang, InKyeomKim 저
...
- 3,000원
In humans and many animal models with chronic progressive renal diseases, angiotensin-converting enzyme (ACE) inhibitor markedly attenuates the progression of nephropathy. Several studies have reported augmented gene expression and redistribution of renal renin in partial nephrectomized rats. Although precise mechanism(s) is not known, the renin-angiotensin system (RAS) may play an important role in the progression of renal diseases. Thus, this study was undertaken to examine the gene...
1126.

The Effect of Electroconvulsive Shock and Cholinergic Drugs on Anterograde Amnesia in Albino Rats

Geon-Ho Bahn, Hwan-Il Chang 대한신경정신의학회 신경정신의학 11 Pages

대한신경정신의학회 신경정신의학 1993, 제 32권 제 4호 9 534-544 (11 pages)

Geon-Ho Bahn, Hwan-Il Chang 저
...
- 4,000원
본 연구는 전기경련충격에 의한 장기적인 전진성 기억장애에 대한 동물모형의 개발과 콜린계 약물이 전기경련충격에 의한 기억장애에 미치는 효과를 알아보고자 실시하였다. 흰쥐에 전기경련 충격을 반복하여 시행한 후 왕복회피상자에서 피동성 도피학습一파지시 험간격을 달리하여 파지시험 결과를 측정하였고, 콜린계 약물들을 용량 및 시기별로 투여하여 파지시험 결과에 미치는 영향을 관찰하여 다음과 같은 결과를 얻었다. 1) 단일 전기경련충격을 받은 집단은 파지기능에 거의 영향을 받지 않았다. 2) 7회에 걸쳐 전기경련충격을...
1127.

Lithium 및 數種睡眼劑가 家兎血中酒精濃度에 미치는 影響에 關한 實驗的研究

金核, 眞鑛建, 李起蘇, 白尙昌 대한신경정신의학회 신경정신의학 12 Pages

대한신경정신의학회 신경정신의학 1972, 제 11권 제 4호 5 243-254 (12 pages)

金核, 眞鑛建, 李起蘇, 白尙昌 저
...
- 4,100원
1128.

Iproniazid 및 Lithium이 가토 혈중주정농도에 미치는 영향에 관한 실험적 연구

정성덕 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1973, 제 12권 제 4호 4 266-274 (9 pages)

정성덕 저
...
- 3,000원
1129.

Fluphenazine , Lithium 및 L- dopa 가 가토 혈중 주정농도에 미치는 영향에 관한 실험적 연구

주문희 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1974, 제 13권 제 4호 12 466-474 (9 pages)

주문희 저
...
- 3,000원
1130.

전기자극 스트레스 또는 심리갈등 스트레스가 횐쥐 비장 임파구 증식과 Interleukin-2 생산능에 미치는 여향

한상진, 양병환, 김정목 대한신경정신의학회 신경정신의학 13 Pages

대한신경정신의학회 신경정신의학 1992, 제 31권 제 2호 2 208-220 (13 pages)

한상진, 양병환, 김정목 저
...
- 4,200원

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