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촉각 자극이 시각장애인의 자세 동요에 미치는 영향
진창원, 이해현, 이승원, 박대성, 송창호 한국시각장애교육재활학회 시각장애연구 12 Pages
한국시각장애교육재활학회 시각장애연구 2007, 제 23권 2호 7 141-152 (12 pages)
본 연구는 시각장애인과 정안인의 정적 균형 능력을 서로 비교하고, 손가락을 통한 가벼운 촉각 자극이 자세 동요에 미치는 영향을 파악하여 자세 동요에 대한 촉각 자극의 보상 작용을 확인하고자 실시하였다. 연구 대상은 시각 손상을 제외한 다른 균형 관련 장애가 없는 시각장애인(전맹) 23명과 균형 장애가 없는 정안인 23명이었다. 30초 동안 압력판 위에서 두 발 모아서기 자세와 촉각 자극을 동반한 두 발 모아서기 자세를 취하게 하고 자세 동요 거리 및 속도를 측정하였으며 다음과 같은 결과를 얻었다. 첫째, 촉각 자극의... -
치아이동에 의한 백서 삼차신경감각핵군내 c-Fos의 발현
민경호(Kyung-Ho Min), 박효상(Hyo-Snag Park), 배용철(Yong-Chul Bae), 성재현(Jae-Hyun Sung) 대한치과교정학회 The Korean Journal of Orthodontics 12 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1998, 제 28권 제 3호 10 441-452 (12 pages)
중추 신경계내 이차 신경 세포체내에 발현되어 neuronal marker로 사용되고 있는 c-fos를 사용한 면역 조직화학법으로 치아이동시 동반되는 동통의 투사경로의 이해에 도움을 주고자하는 것이다. 생후 9주령의 210gm내외의 Sprague-Dawley계 응성 백서 21마리를 교정력을 가하지 않고 마취만을 시행한 정상대조군과 교정력 적용 시간 경과에 따라 1시간, 3시간, 6시간, 12시간, 1일, 3일 군으로 나우어 각 해당 시간동안 상악 우측 제 1대구치와 상악 우측 측절치사이에 Ni-Ti coil spring를 결찰하여 30gm내외의 지속적인 교정력을 가한... -
Microarray Analysis of Oxygen-Glucose-Deprivation Induced Gene Expression in Cultured Astrocytes
DaeHyunJoo, HyungSooHan, JaeSikPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.5 7 263-272 (10 pages)
in maintaining neuronal viability both under normal conditions and during stress such as ischemia, studies of the astrocytic response to stress are essential to understand many types of brain pathology. The microarray system permitted screening of large numbers of genes in biological or pathological processes. Therefore, the gene expression patterns in the in vitro model of astrocytes following exposure to oxygen-glucose deprivation (OGD) were evaluated by using the microarray analysis. Primary... -
Changes of CA1 Excitability in Rats after Prenatal Methylazoxymethanol Treatment
Sung-YoungJang, In-SunChoi, Jin-HwaCho, Il-SungJang, Maan-GeeLee, Byung-JuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.1 3 13-18 (6 pages)
When GABAA receptor antagonists were blocked with 10μM bicuculline, the amplitude of the second population spike of the MAM-treated of rats was similar to that of the first population spike, as was in the control rats. The MAM-treated rats had fewer somatostatin and parvalbumin-immunoreactive neurons than the control rats. These results suggest that the enhanced neuronal responsiveness of the in vivo recording of the CA1 in this animal model may involve a reduction of CA1 inhibition. -
Calcium Influx is Responsible for Afterdepolarizations in Rat Hippocampal Dentate Granule Cells
Won-SunParkSuk-HoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.3 3 143-148 (6 pages)
in CA3 region. Their electrical activities are known to be closely associated with seizure activity as well as memory acquisition. Since action potential is a stereotypic phenomena which is based on all-or-none principle of Na current, the neuronal firing pattern is mostly dependent on afterpotentials which follows the stereotypic Na spike. Granule cells in dentate gyrus show afterdepolarization (ADP), while interneurons in dentate gyrus have afterhyperpolarizaton. In the present... -
Characterization of Norepinephrine Release in Rat Posterior Hypothalamus Using in vivo Brain Microdialysis
Ki-WugSung, SeongYunKim, OkNyuKim, SangBokLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.1 2 9-14 (6 pages)
values. But, DOPAC and HVA outputs remained unchanged. Pargyline, an irreversible monoamine oxidase inhibitor, i.p. administered at a dose of 75 mg/kg, increased NE output (maximum 165%), while decreased DOPAC and HVA outputs (maximum 13 and 12%, respectively). These results indicate that NE in dialysate from the rat posterior hypothalamus were neuronal origin, and that manipulations which profoundly affected the levels of extracellular neurotransmitter had also effects on metabolite levels. -
Responsiveness of Dendrites to the Glutamate Applied Focally with Pressure Ejector and Iontophoresis into Hippocampal Slices
JinHyukKim, HongKeeShin, HyunJuChang, HyeYoungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.6 2 457-466 (10 pages)
potentials. To evoke long-term change of synaptic plasticity, we adopted θ-burst in the glutamate train ejection. The θ-burst decreased the amplitude of glutamate response by 60%. However, after θ-burst glutamate train ejection, the calcium dependent action potential appeared. These results indicated that the focal application of glutamate on the neuronal dendrite induced response similar to the synaptic transmission and the trains of glutamate ejection modulated the change of AMPA receptor. -
The Inhibitory Effect of Opioid on the Hyperpolarization-Activated Cation Currents in Rat Substantia Gelatinosa Neurons
GeunHeeSeol, JunKim, SunHeeCho, WonKiKim, JongWhanKim, SangJeongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.5 2 373-380 (8 pages)
whole-cell voltage-clamp recording in rat spinal brain slices. Hyperpolarizing voltage steps revealed slowly activating currents in a subgroup of neurons. The half-maximal activation and the reversal potential of the current were compatible to neuronal Ih. DAMGO (1μM), a selective- opioid agonist, reduced the amplitude of Ih reversibly. This reduction was dose-dependent and was blocked by CTOP (2μM), a selective μ-opioid antagonist. DAMGO shifted the voltage dependence of activation to more... -
Mechanism of Epibatidine-Induced Catecholamine Secretion in the Rat Adrenal Gland
Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.3 8 259-270 (12 pages)
by the simultaneous perfusion of epibatidine, but those after 2nd period were not affected. Taken together, these experimental data suggest that epibatidine causes catecholamine secretion in a calcium dependent fashion from the perfused rat adrenal gland through activation of neuronal cholinergic (nicotinic and muscarinic) receptors located in adrenomedullary chromaffin cells. It also seems that epibatidine-evoked catecholamine release is not relevant to stimulation of histaminergic receptors. -
Increase of Peroxynitrite Production in the Rat Brain Following Transient Forebrain Ischemia
HeeJoonKimSeongYunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.3 2 205-212 (8 pages)
min, this change was also observed in the lateral striatal region and the lateral septal nucleus 2∼3 days after reperfusion. The cresyl violet staining of adjacent sections showed that neuronal cell death was induced in parallel with the nitrotyrosine immunoreactivity in the hippocampal CA1 area and the lateral striatal region. Our findings suggest that oxygen free radical accumulation and consequent peroxynitrite production play a role in neuronal death caused by cerebral ischemia-reperfusion.


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