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1201.

Regulation of Salt and Volume Transport along the Nephron during Acute Systolic Hypertension

AliciaA.McDonough, YibinZhang, ClaraE.Magyar, AustinK.Mircheff 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 1 541-547 (7 pages)

AliciaA.McDonough, YibinZhang, ClaraE.Magyar, AustinK.Mircheff 저
...
- 3,000원
1202.

Increased Activity of Large Conductance Ca2+-Activated K+ Channels in Negatively-Charged Lipid Membranes

JinBongParkPanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 15 529-539 (11 pages)

JinBongParkPanDongRyu 저
...
- 4,000원
The effects of membrane surface charge originated from lipid head groups on ion channels were tested by analyzing the activity of single large conductance Ca2⁢-activated K⁢ (maxi K) channel from rat skeletal muscle. The conductances and open-state probability (Po) of single maxi K channels were compared in three types of planar lipid bilayers formed from a neutral phosphatidylethanolamine (PE) or two negatively-charged phospholipids, phosphatidylserine (PS) and phosphatidylinositol...
1203.

Pharmacological Characterization of Synthetic Tetrahydroisoquinoline Alkaloids, YS 51 and YS 55, on the Cardiovascular System

Ki-ChurlChang, Young-JinKang, Young-SooLee, Won-SeogChong, Hye-SookYun-Choi, Duck-HyongLee, Jae-ChunRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 8 461-469 (9 pages)

Ki-ChurlChang, Young-JinKang, Young-SooLee, Won-SeogChong, Hye-SookYun-Choi, Duck-HyongLee, Jae-ChunRyu 저
...
- 3,000원
Tetrahydroisoquinoline (THI) alkaloids can be considered as cyclized derivatives of simple phenylethylamines, and many of them, especially with 6,7-disubstitution, demonstrate relatively high affinity for catecholamines. Two -OH groups at 6 and 7 positions are supposed to be essential to exert ㄂-receptor activities. However, it is not clear whether -OH at 6,7 substitution of THIs also shows ㄁-adrenoceptor activities. In the present study, we investigated whether -OH or -OCH3...
1204.

Rapid Induction of mRNA for Prostaglandin H Synthase in Ovine Meningeal Fibroblasts

MyeongJinNam, ClaraThore, DavidBusija 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 5 435-441 (7 pages)

MyeongJinNam, ClaraThore, DavidBusija 저
...
- 3,000원
We examined effects of interleukin 1α (IL1α) and phorbol 12, 13 dibutyrate (PDB), an activator of protein kinase C, on mRNA for Prostaglandin H synthase (PGHS) and prostanoid production in cultured ovine meningeal fibroblasts. Immuno- and morphologically-identified fibroblasts were derived from cerebral cortex and white matter from fetal lambs (approximately 120 days gestation) and grown to confluence on glass coverslips in 12 well plates. Levels of prostaglandin F2α and the stable...
1205.

Inhibitory Effect of Caffeine on Carbachol-Induced Nonselective Cationic Current in Guinea-Pig Gastric Myocytes

SungJoonKim, KyungWanMin, YoungChulKim, SangJinLee, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 10 353-359 (7 pages)

SungJoonKim, KyungWanMin, YoungChulKim, SangJinLee, InsukSo, KiWhanKim 저
...
- 3,000원
In gastrointestinal smooth muscle, muscarinic stimulation by carbachol (CCh) activates nonselective cation channel current (ICCh) which is facilitated by intracellular [Ca2⁢] increase. Caffeine is widely used in experiments to mobilize Ca2⁢ from intracellular stores. This study shows a strong inhibitory effect of caffeine on ICCh in guinea-pig gastric myocyte. In this study, the underlying mechanism of the inhibitory effect of caffeine was investigated. ICCh was completely...
1206.

Nitric Oxide Impairs the Recovery from Hemorrhagic Hypotension in Conscious Rats

Yoon-yubParkYoung-ManLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 9 345-351 (7 pages)

Yoon-yubParkYoung-ManLee 저
...
- 3,000원
The role of nitric oxide (NO) in the hemorrhagic hypotension was examined using a NO synthase inhibitor, Nω-nitro-L-arginine methyl ester (L-NAME), in conscious rats. The rats were bled at a constant rate (2 ml/kg/min) through a femoral arterial catheter until the mean arterial pressure (MAP) was reduced by 50 mmHg. We studied the responses to hemorrhage under normal condition (Control) and after the pretreatment with 3 doses of L-NAME (1.6, 8, 40 mg/kg i.v. of NOX1.6, NOX8, and NOX40,...
1207.

Ethanol Prevents from Acetaminophen Inducible Hepatic Necrosis by Inhibiting its Metabolic Activation in Mice

Sun-MeeLee, Tai-SoonCho, Young-NamCha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 15 261-269 (9 pages)

Sun-MeeLee, Tai-SoonCho, Young-NamCha 저
...
- 3,000원
Concomitant administration of a single acute dose of ethanol (4 g/kg) protected mice from the hepatocellular injury observed upon administration of a large dose of acetaminophen (400 mg/kg). This was evidenced by the normal histological appearances of liver sections and by the lowered serum aminotransferase activities in mice treated with ethanol and acetaminophen together. In the mice treated with acetaminophen alone, along with the hepatic necrosis, the hepatic microsomal aminopyrine...
1208.

Inhibitory Effects of Ginseng Saponins on c-fos mRNA Expression and the Proliferation of Rat Aortic Vascular Smooth Muscle Cells Stimulated by Angiotensin II

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 8 201-207 (7 pages)

WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 저
...
- 3,000원
To evaluate the possibility that the ginseng saponins could be developed as an anti-arteriosclerotic agent, we examined the inhibitory effects of ginseng saponins (total saponin[TS], panaxatriol[PT], panaxadiol[PD]) on the expression of c-fos mRNA and the proliferation of cultured rat aortic vascular smooth muscle cells (VSMCs) stimulated by angiotensin II (Ang II). TS and PT (1.0 mg/ml) suppressed c-fos mRNA induction in VSMCs stimulated by 10-5 M Ang II. The order of inhibitory potency was...
1209.

Sensory Inputs to Upper Cervical Spinal Neurons Projecting to Midbrain in Cats

JongHoKim, Han-SeongJeong, Jong-SeongPark, Jong-KeunKim, Sah-HoonPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 2 9-19 (11 pages)

JongHoKim, Han-SeongJeong, Jong-SeongPark, Jong-KeunKim, Sah-HoonPark 저
...
- 4,000원
1210.

Effect of t-butylhydroperoxide on Na+-dependent Glutamate Uptake in Rabbit Brain Synaptosome

HyunJeLeeYongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 3 367-376 (10 pages)

HyunJeLeeYongKeunKim 저
...
- 3,000원
The effect of an organic peroxide, t-butylhydroperoxide (t-BHP), on glutamate uptake was studied in synaptosomes prepared from cerebral cortex. t-BHP inhibited the Na+-dependent glutamate uptake with no change in the Na+-independent uptake. This effect of t-BHP was not altered by addition of Ca2+ channel blockers (verapamil, diltiazem and nifedipine) or PLA2 inhibitors (dibucaine, butacaine and quinacrine). However, the effect was prevented by iron chelators (deferoxamine and phenanthroline)...

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