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태수술에 대한 이해와 구순구개열 환자에서의 적용
김성민, 박정민, 명훈, 최진영, 이종호, 정필훈, 김명진 대한구순구개열학회 대한구순구개열학회지 10 Pages
대한구순구개열학회 대한구순구개열학회지 2008, 제 11권 2호 1 49-58 (10 pages)
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Curriculum-Based Measurement: An Alternative Method to Evaluate Students with Academic Underachievement
Kamonwan Tangdhanakanond, Dong Hun Lee 한국교육치료학회 교육치료연구 11 Pages
한국교육치료학회 교육치료연구 2010, Vol.2 No.1 6 91-101 (11 pages)
Curriculum?based measurement (CBM) is a method of systematically assessing students’ academic skills by directly using the academic materials taken from the school curriculum or from what they are being instructed. CBM is one of the alternative evidence-based assessment methods that could be used to evaluate students with existing academic underachievement and to determine the needs for instructional change to improve performance of underachieving students. This paper provides readers with the... -
Antipruritic effect of curcumin on histamine-induced itching in mice
Han Kyu Lee, Seok Bum Park, Su-youne Chang, Sung Jun Jung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 8 547-554 (8 pages)
Itching is a common clinical symptom of skin disease that significantly affects a patient’s quality of life. Transient receptor potential vanilloid 1 (TRPV1) receptors of keratinocytes and peripheral nerve fibers in skin are involved in the regulation of itching as well as pain. In this study, we investigated whether curcumin, which acts on TRPV1 receptors, affects histamine-induced itching in mice, using behavioral tests and electrophysiological approaches. We found that histamine-induced... -
Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B
KyuPilLee, HyunJinKim, DongkiYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 10 91-99 (9 pages)
Protein phosphatase 1 (PP1) is involved in various signal transduction mechanisms as an extensive regulator. The PP1 catalytic subunit (PP1c) recognizes and binds to PP1-binding consensus residues (FxxR/KxR/K) in NBCe1-B. Consequently, we focused on identifying the function of the PP1-binding consensus residue, 922FMDRLK927, in NBCe1-B. Using site-directed mutagenesis and co-immunoprecipitation assays, we revealed that in cases where the residues were substituted (F922A, R925A, and K927A) or... -
The advantage of topographic prominence-adopted filter for the detection of short-latency spikes of retinal ganglion cells
JungryulAhn, Myoung-HwanChoi, KwangsooKim, SolomonS.Senok, Dong-ilDanCho, Kyo-inKoo, YongsookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 10 555-563 (9 pages)
Electrical stimulation through retinal prosthesis elicits both short and long-latency retinal ganglion cell (RGC) spikes. Because the short-latency RGC spike is usually obscured by electrical stimulus artifact, it is very important to isolate spike from stimulus artifact. Previously, we showed that topographic prominence (TP) discriminator based algorithm is valid and useful for artifact subtraction. In this study, we compared the performance of forward backward (FB) filter only vs. TP-adopted... -
Seasonal acclimation in sudomotor function evaluated by QSART in healthy humans
YoungOhShin, Jeong-BeomLee, Jeong-HoKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 7 499-505 (7 pages)
The quantitative sudomotor axon reflex testing (QSART) is a classic test of routine postganglionic sudomotor function. We investigated sudomotor function by QSART after summer (July 2012) and winter (January 2013) seasonal acclimation (SA) in the Republic of Korea. QSART with acetylcholine (ACh) iontophoresis were performed to determine directly activated (DIR) and axon reflex-mediated (AXR1, 2) sweating rate. Onset time of axon reflex, activated sweat gland density (ASGD), activated sweat gland... -
Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.
Wan-SuKim, WooJinChoi, SunwooLee, WooJoongKim, DongChaeLee, , UyDongSohn, Hyoung-ShikShin, WonyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 4 21-28 (8 pages)
The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin- containing extracts had anti-inflammatory effects. Of these, the acetone extract had the greatest inhibitory effect on lipopolysaccharide-induced nitric oxide (NO), prostaglandin E2 (PGE2), and pro- inflammatory cytokine (IL-1β, IL-6, and IL-10) production. Antioxidant activity evaluations revealed... -
Ursolic Acid-Induced Elevation of Serum Irisin Augments Muscle Strength During Resistance Training in Men
HyunSeokBang, DaeYunSeo, YongMinChung, Kyoung-MoOh, JungJunPark, FigueroaArturo6, Seung-HunJeong, NariKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 13 441-446 (6 pages)
Ursolic acid (UA), a type of pentacyclic triterpenoid carboxylic acid purified from natural plants, can promote skeletal muscle development. We measured the effect of resistance training (RT) with/without UA on skeletal muscle development and related factors in men. Sixteen healthy male participants (age, 29.37±5.14 years; body mass index=27.13±2.16 kg/m2) were randomly assigned to RT (n=7) or RT with UA (RT+UA, n=9) groups. Both groups completed 8 weeks of intervention consisting of 5 sets of... -
KHG26792 Inhibits Melanin Synthesis in Mel-Ab Cells and a Skin Equivalent Model
HailanLi, JiKim, Hoh-GyuHahn, JunYun, Hyo-SoonJeong, Hye-YoungYun, KwangJinBaek, NyounSooKwon, YoungSilMin, Kyoung-ChanPark, Dong-SeokKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 8 249-254 (6 pages)
The purpose of this study is to characterize the effects of KHG26792 (3-(naphthalen-2-yl(propoxy) methyl)azetidine hydrochloride), a potential skin whitening agent, on melanin synthesis and identify the underlying mechanism of action. Our data showed that KHG26792 significantly reduced melanin synthesis in a dose-dependent manner. Additionally, KHG26792 downregulated microphthalmiaassociated transcription factor (MITF) and tyrosinase, the rate-limiting enzyme in melanogenesis, although... -
Identification and Functional Characterization of Novel Genetic Variations in the OCTN1 Promoter
HyoJinPark, JiHaChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 12 169-175 (7 pages)
Human organic cation/carnitine transporter 1 (OCTN1) plays an important role in the transport of drugs and endogenous substances. It is known that a missense variant of OCTN1 is significantly associated with Crohn’s disease susceptibility. This study was performed to identify genetic variants of the OCTN1 promoter in Korean individuals and to determine their functional effects. First, the promoter region of OCTN1 was directly sequenced using genomic DNA samples from 48 healthy Koreans. OCTN1...


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