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Effectiveness of 99mTc-tetrofosmin for assessment of heart functions in micropigs
Min Young Lee, Sang Hun Lee, Jae Hong Park, Jung Sun Heo, Yu Jin Lee, Han Na Suh, Jung Jun Min, Young Soon Seo, Ho Jae Han 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 3호 4 223-227 (5 pages)
This study examined the suitability of a nuclear imaging technique using 99mTc-tetrofosmin as an agent to assess the heart functions of healthy micropigs. The mean age of the pigs was 360 days (male), and the mean body weight was 35.3 kg ranging from 34.5-36 kg. There were no significant perfusion defects in any of the reconstructed images. Gated single-photon emission computed tomography imaging can be used to calculate the ventricular volume and ejection fraction (EF). In this case, an EF of... -
Establishment of a canine spinal cord injury model induced by epidural balloon compression
Ji-Hey Lim, Chang-Su Jung, Ye-Eun Byeon, Wan Hee Kim, Jung-Hee Yoon, Kyung-Sun Kang, Oh-kyeong Kweon 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 13 89-94 (6 pages)
A model that provides reproducible, submaximal yet sufficient spinal cord injury is needed to allow experiments leading to development of therapeutic techniques and prediction of clinical outcome to be conducted. This study describes an experimental model for spinal cord injury that uses three different volumes of balloon inflation and durations of compression to create a controlled gradation outcome in adult dogs. Twenty-seven mongrel dogs were used for this study. A 3-french embolectomy... -
Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen
Yoot Mo Lee, Min Jae Seong, Jae Woong Lee, Yong Kyung Lee, Tae Myoung Kim, Sang-Yoon Nam, Dae Joong Kim, Young Won Yun, Tae Seon 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 5 27-38 (12 pages)
Bisphenol A (BPA), a ubiquitous environmental contaminant, has been shown to cause developmental toxicity and carcinogenic effects. BPA may have physiological activity through estrogen receptor (ER) -α and -β, which are expressed in the central nervous system. We previously found that exposure of BPA to immature mice resulted in behavioral alternation, suggesting that overexposure of BPA could be neurotoxic. In this study, we further investigated the molecular neurotoxic mechanisms of BPA. BPA... -
Organotypic slice culture of the hypothalamic paraventricular nucleus of rat
Eun Seong Cho, So Yeong Lee, Jae-Yong Park, Seong-Geun Hong, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 3 15-20 (6 pages)
Organotypic slice cultures have been developed as an alternative to acute brain slices because the neuronal viability and synaptic connectivity in these cultures can be preserved well for a prolonged period of time. This study evaluated a stationary organotypic slice culture developed for the hypothalamic paraventricular nucleus (PVN) of rat. The results showed that the slice cultures maintain the typical shape of the nucleus, the immunocytochemical signals for oxytocin, vasopressin, and... -
Comparative analysis of heart functions in micropigs and conventional pigs using echocardiography and radiography
Min Young Lee, Sang Hun Lee, Seung Gon Lee, Soo Hyun Park, Chai Yong Lee, Kye Hun Kim, Sun Ho Hwang, Sang Yub Lim, Young Keun Ah 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 2 7-14 (8 pages)
The production of miniature animals has been suggested for use in organ transplantation. At present, many of the studies about application of animal organs to human have been focused on pigs because of the number of advantages involved and due to their similarities with human. However, a physiological analysis of the organs to be transplanted has not yet been carried out. Therefore, this study analyzed whether or not there were physiological and morphological differences in the hearts of... -
Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil
I. Reginald Obidike, Igwebuike U. Maduabuchi, Shoyinka S.V. Olumuyiwa 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 1 1-5 (5 pages)
Potential negative effects of exposure to Nigerian Qua Iboe Brent crude oil on the reproductive system of male rats was investigated. Forty Sprague-Dawley rats were used for the experiment. Exposure to Nigerian Qua Iboe Brent crude oil was achieved via oral administration of increasing doses (0.1, 0.2, and 0.4 ml/rat) every other day for 4 weeks. Cauda epididymal sperm reserves and relative weights of the testes as well as histological features of the testes of rats that received the crude oil... -
Risk factors for delayed conception in Korean dairy herds
Ill-Hwa Kim, Hyun-Gu Kang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 13 381-385 (5 pages)
Delayed conception is defined as an interval of greater than 90 days postpartum before a cow becomes pregnant again. In this study, the risk factors for delayed conception in Korean dairy herds were determined by evaluating several reproductive factors in individual cows. The following data was recorded from 1,012 pregnancies in eight dairy herds (designated A-H) from July 2001 to June 2006: herd, cow parity, repeated animal (cows included 2, 3, or more times), calving season, calving condition... -
Pharmacokinetics, urinary excretion and dosage regimen of levofloxacin following a single intramuscular administration in cross bred calves
Vinod K. Dumka, Anil K. Srivastava 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 5 333-337 (5 pages)
The pharmacokinetics and urinary excretion following single intramuscular administration of levofloxacin at a dose of 4 mg/kg was investigated in seven male cross bred calves. Appreciable plasma concentration of levofloxacin (0.38 ± 0.06 μg/ml) was detected at 1 min after injection and the peak plasma level of 3.07 ± 0.08 μg/ml was observed at 1 h. The drug level above MIC90 in plasma was detected up to 12 h after administration. Rapid absorption of the drug was also evident by the high... -
Advancing parity is associated with high milk production at the cost of body condition and increased periparturient disorders in dairy herds
Ji-Yeon Lee, Ill-Hwa Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 12 161-166 (6 pages)
The objectives of this study were to determine the effects of parity on milk production, body condition change, periparturient health, and culling in Korean dairy herds. The data utilized included; milk yield, body condition score, cow parity, calving condition, periparturient disorders, culling, and reproductive status, which were recorded from 1290 calvings in eight dairy herds. The mean milk yield in cows over 305 days increased with increasing parity (p < 0.01). Cows with parities of 3, 4,... -
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits
Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 10 151-155 (5 pages)
This study examined the effect of experimentally induced fever on the pharmacokinetics of cefepime (75 mg/kg BW) administered intramuscularly to six rabbits. The study was carried out in two consecutive phases separated by a two-week washout period. An infection was induced by an intravenous inoculation of 5 × 108 colony-forming units of Escherichia coli 24 h before the pharmacokinetic investigation. A quantitative microbiological assay was employed to measure the plasma cefepime concentrations...


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