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1291.

Neuroprotective Effects of AMP-Activated Protein Kinase on Scopolamine Induced Memory Impairment

Soo-JeongKim, Jun-HoLee, Hwan-SuckChung, Joo-HyunSong, JoohunHa, HyunsuBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 11 331-338 (8 pages)

Soo-JeongKim, Jun-HoLee, Hwan-SuckChung, Joo-HyunSong, JoohunHa, HyunsuBae 저
...
- 3,000원
AMP-activated protein kinase (AMPK), an important regulator of energy metabolism, is activated in response to cellular stress when intracellular levels of AMP increase. We investigated the neuroprotective effects of AMPK against scopolamine-induced memory impairment in vivo and glutamate-induced cytotoxicity in vitro. An adenovirus expressing AMPK wild type alpha subunit (WT) or a dominant negative form (DN) was injected into the hippocampus of rats using a stereotaxic apparatus. The AMPK...
1292.

Synaptic Plasticity in Mouse Models of Autism Spectrum Disorders

LeeyupChung, AlexraL.Bey, Yong-HuiJiang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.6 1 369-378 (10 pages)

LeeyupChung, AlexraL.Bey, Yong-HuiJiang 저
...
- 3,000원
Analysis of synaptic plasticity together with behavioral and molecular studies have become a popular approach to model autism spectrum disorders in order to gain insight into the pathosphysiological mechanisms and to find therapeutic targets. Abnormalities of specific types of synaptic plasticity have been revealed in numerous genetically modified mice that have molecular construct validity to human autism spectrum disorders. Constrained by the feasibility of technique, the common regions...
1293.

Toll-like Receptor3-mediated Induction of Chemokines in Salivary Epithelial Cells

JingchaoLi, MiYoungJeong, JiHyunBae, YongHwanShin, MeihongJin, SungMinHang, JeongChaiLee, SungJoongLee, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.4 6 235-240 (6 pages)

JingchaoLi, MiYoungJeong, JiHyunBae, YongHwanShin, MeihongJin, SungMinHang, JeongChaiLee, SungJoongLee, KyungpyoPark 저
...
- 3,000원
Toll-like receptors (TLRs) functionally expressed in salivary epithelial cells, but their roles remain elusive. Among TLRs family, TLR3 is activated by dsRNA, a byproduct of viral infection. The aim of this study was to investigate the role of TLR3 in the inflammatory immune responses using HSG cells. Reverse transcriptase-polymerase chain reaction (RT-PCR), real-time PCR and ELISA were performed to identify expression of TLRs and TLR3-mediated chemokine inductions. The chemotaxis assay of...
1294.

정신분열병에서의 도파민 D5 수용체 유전자 염기배열 변이(T978C)에 관한 연관연구

김준모, 조주연, 박두병 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1999, 제 38권 제 2호 16 399-407 (9 pages)

김준모, 조주연, 박두병 저
...
- 3,000원
연구목적： 본 연구는 정신분열병의 유력한 후보유전자인 DRD5 유전자의 T978C 변이를 통해 다형성 분포를 조사하 였다. 정신분열병 환자군과 정상대조군에서 T978C 변이의 발생 빈도가 어느정도이며, 차이가 있는지 알아 보고 T978C 변이가 정신분열병과 상관성이 있는것인지 밝혀보고자 시행하였다. 방 법： 정신분열병 환자군 100명과 정상대조군 100명에서 도파민 D5수용체 유전자의 T978C변이의 분포를 조 사하였다. 결 과： 정신분열병 환자군과 정상대조군 사이에서 T978C 변이의 유전자형의 빈도와 동형접합체 비율의 차이는...
1295.

Chlorpromazine이 전기경련 충격에 의한 흰쥐 대뇌피질 c-fos 및 jun B 발현에 미치는 영향

강웅구, 권택술, 김용식 대한신경정신의학회 신경정신의학 8 Pages

대한신경정신의학회 신경정신의학 1995, 제 34권 제 5호 25 1492-1499 (8 pages)

강웅구, 권택술, 김용식 저
...
- 3,000원
1296.

Transformation of Rabbit Proximal Tubule Cells by Strontium Phosphate Transfection with a Plasmid Containing SV4O Early Region Genes

Han, Ho-Jae, Taub, Mary L., 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 14 233-240 (8 pages)

Han, Ho-Jae, Taub, Mary L., 저
...
- 3,000원
in a hormone defined medium. Domes were also observed in some of the cultures. 2. r-glutamyl transpeptidase activity was equivalent to that observed in primary renal proximal tubule cell cultures. 3. Transformed cells with pRSVT form tubules in matrigel following 20 passages. 4. Genomic DNA of transformants was digested with either the restriction enzyme Xba or BamH1. A band of approximately 7.5kb was detected with Xba. Three BamH1 bands were detected at approximately 15 kb, 6.5 kb, and 3 kb.
1297.

Immunocytochemical Study on the Translocation Mechanism of Glucose Transporters by Insulin

Hah, Jong-Sik, Kim, Ku-Ja 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 2 123-138 (16 pages)

Hah, Jong-Sik, Kim, Ku-Ja 저
...
- 4,500원
The mechanism of insulin action to increase glucose transport is attributed to glucose transporter translocation from intracellular storage pools to the plasma membrane in insulin-sensitive cells. The present study was designed to visualize the redistribution of the glucose transporter by means of an immunogold labelling method. Our data clearly show that glucose transporter molecules were visible by this method. According to the method this distribution of glucose transporters between cell...
1298.

Genome-wide Identification, Classification, and Expression Analysis of the Receptor-Like Protein Family in Tomato

Won-Hee Kang, Seon-In Yeom 한국식물병리학회 The Plant Pathology Journal 10 Pages

한국식물병리학회 The Plant Pathology Journal 2018, 34권 5호 9 435-444 (10 pages)

Won-Hee Kang, Seon-In Yeom 저
...
- 3,000원
to tissue specific RNA-seq data, 71 RLPs were expressed in at least one of the following tissues: root, leaf, bud, flower, or fruit. Several genes had expression patterns that were tissue specific. In addition, tomato RLP expression profiles after infection with different pathogens showed distinguish gene regulations according to disease induction and resistance response as well as infection by bacteria and virus. Notably, Some RLPs were highly and/ or unique expressed in susceptible tomato to...
1299.

The Plant Cellular Systems for Plant Virus Movement

한국식물병리학회 The Plant Pathology Journal 16 Pages

한국식물병리학회 The Plant Pathology Journal 2017, 33권 3호 1 213-228 (16 pages)

저
...
- 4,500원
Plasmodesmata (PDs) are specialized intercellular channels that facilitate the exchange of various molecules, including sugars, ribonucleoprotein complexes, transcription factors, and mRNA. Their diameters, estimated to be 2.5 nm in the neck region, are too small to transfer viruses or viral genomes. Tobacco mosaic virus and Potexviruses are the most extensively studied viruses. In viruses, the movement protein (MP) is responsible for the PD gating that allows the intercellular movement of viral...
1300.

Transcriptome Analysis of Early Responsive Genes in Rice during Magnaporthe oryzae Infection

한국식물병리학회 The Plant Pathology Journal 12 Pages

한국식물병리학회 The Plant Pathology Journal 2014, 30권 4호 2 343-354 (12 pages)

저
...
- 4,100원
300 K tilling microarray to rice leaves infected with compatible and incompatible M. oryzae strains. Prior to the microarray experiment, total RNA was validated by measuring the differential expression of rice defense-related marker genes (chitinase 2, barwin, PBZ1, and PR-10) by RT-PCR, and phytoalexins (sakuranetin and momilactone A) with HPLC. Microarray analysis revealed that 231 genes were up-regulated (>2 fold change, p < 0.05) in the incompatible interaction compared to the...

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