주제분류
더보기(11)자료유형
발행기관
- 한국식물병리학회(66)
- 대한수의학회(63)
- 대한생리학회-대한약리학회(58)
- 대한약리학회(9)
- 대한신경정신의학회(5)
- 물리치료재활과학회(4)
- 한국기초간호학회(4)
- 한국탄소학회(4)
- 한방비만학회(4)
- 생화학분자생물학회(3)
- 한국생명과학회(3)
- 한국미생물학회(2)
- 한국응용약물학회(2)
- 국민연금연구원(1)
- 대한고령친화산업학회(1)
- 대한신경계작업치료학회(1)
- 대한치과교정학회(1)
- 대한치과이식임플란트학회(1)
- 대한화학회(1)
- 이화여자대학교 교과교육연구소(1)
- 한국고분자학회(1)
- 한국대학박물관협회(1)
- 한국미생물생명공학회(1)
- 한국분자세포생물학회(1)
- 한국생물공학회(1)
- 한국웰니스학회(1)
- 한국유가공기술과학회(1)
- 한국의학교육학회(1)
- 한국청각언어재활학회(1)
- 환태평양유아교육연구학회(1)
간행물
- THE PLANT PATHOLOGY JOURNAL (62)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(58)
- JOURNAL OF VETERINARY SCIENCE(45)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(11)
- 대한약리학잡지(9)
- 대한수의학회 학술대회발표집(7)
- 신경정신의학(5)
- CARBON LETTERS(4)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(4)
- PHYSICAL THERAPY REHABILITATION SCIENCE(4)
- 대한한방비만학회지(4)
- 식물병연구(4)
- JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY(3)
- 생명과학회지(3)
- BIOMOLECULES & THERAPEUTICS(2)
- ASIA-PACIFIC JOURNAL OF RESEARCH IN EARLY CHILDHOOD EDUCATION(1)
- AUDIOLOGY AND SPEECH RESEARCH(1)
- BIOTECHNOLOGY AND BIOPROCESS ENGINEERING(1)
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY(1)
- JOURNAL OF DENTAL IMPLANT RESEARCH(1)
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY(1)
- KOREAN JOURNAL OF MEDICAL EDUCATION(1)
- MACROMOLECULAR RESEARCH(1)
- MOLECULES AND CELLS(1)
- THE JOURNAL OF MICROBIOLOGY(1)
- THE KOREAN JOURNAL OF ORTHODONTICS(1)
- 고문화(1)
- 교과교육학연구(1)
- 국민연금연구원 연구보고서(1)
- 대한고령친화산업학회지(1)
- 미생물과 산업(1)
- 재활치료과학(1)
- 한국웰니스학회지(1)
- 한국유가공기술과학회지(1)
전체 선택해제
총 244건 검색
본문검색 결과만 보기
-
Role of Shc and Phosphoinositide 3-Kinase in Heregulin-Induced Mitogenic Signaling via ErbB3
MyongSooKimJohnG.Kol 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 9 497-506 (10 pages)
receptor protein tyrosine kinases. When expressed in NIH/3T3 cells, ErbB3 can form heterodimeric coreceptor with endogenous ErbB2. Among known intracellular effectors of the ErbB2/ErbB3 are mitogen-activated protein kinase (MAPK) and phosphoinositide (PI) 3-kinase. In the present study, we studied relative contributions of above two distinct signaling pathways to the heregulin-induced mitogenic response via activated ErbB3. For this, clonal NIH-3T3 cell lines expressing wild-type ErbB3 and ErbB3... -
Different Effects of Dopamine on Differential Rotational Mobility between Inner and Outer Monolayer of Synaptosomal Plasma Membrane Vesicles Isolated from Bovine Brain
Hyun-GangKim, Chang-HwaChoi, Inn-SeKim, In-KyoChung, Goon-JaeCho, Hye-OckJang6, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 10 409-415 (7 pages)
Fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) was used to evaluate the effects of dopamine·HCl on the range of the rotatioanl mobility of bulk bilayer structure of the synaptosomal plasma membrane vesicles (SPMV) isolated from whole bovine brain. In a dose-dependent manner, dopamine decreased the anisotropy (γ), limiting anisotropy (γ∞) and order parameter (S) of DPH in the membranes. These indicate that dopamine increased the rotational mobility of the probe in the... -
Ritanserin, a 5HT2/1C Receptor Antagonist, Does Not Block Cocaine- Induced Behavioral Alterations and zif268 mRNA Expression in the Striatum of the Rats
EunSangChoeJongYeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 3 355-359 (5 pages)
Cocaine induces immediate early gene expression and behavioral changes by blocking dopamine transporters in the terminals of nigrostriatal neurons in the striatum. The pharmacological role of serotonin 2/1C (5HT2/1C) receptors in cocaine-induced expression of zif268 (NGFI-A, egr1 and Krox-24) mRNA, a member of the zinc finger, was investigated using quantitative in situ hybridization histochemistry in vivo. Behavioral alterations induced by cocaine were also monitored in relation with blockade... -
Glucose/Oxygen Deprivation Induces Release of [3H]5-hydroxytryptamine Associated with Synapsin 1 Expression in Rat Hippocampal Slices
EunMiPark, SangHuiChu, KyungEunLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 2 347-353 (7 pages)
were also investigated. GOD for 20 minutes enhanced release of [3H]5-HT, which was in part blocked by the NMDA receptor antagonist, APV. The augmented expression of synapsin 1 during GOD for 20 minutes, which was also in part prevented by APV. In contrast, the expression of syntaxin and SNAP-25 were not altered during GOD. These results suggest that ischemic insult induces release of [3H]5-HT associated with synapsin 1, synaptic vesicular protein, via activation of NMDA receptor in part. -
The Effect of NO Donor on Contraction, Cytosolic Ca2+ Level and Ionic Currents in Guinea-pig Ileal Smooth Muscle
Seong-ChunKwon, Ki-YoungPark, Duck-SunAhn, Young-HoLee, Bok-SoonKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 5 33-40 (8 pages)
This study was designed to clarify the mechanism of the inhibitory action of a nitric oxide (NO) donor, 3-morpholino-sydnonimine (SIN-1), on contraction, cytosolic Ca2 level ([Ca2]i), and ionic currents in guinea-pig ileum. SIN-1 (0.01∼100μM) inhibited 25 mM KCl- or histamine (10μM)-induced contraction in a concentration-dependent manner. SIN-1 reduced both the 25 mM KCl- and the histamine-stimulated increases in muscle tension in parallel with decreased [Ca2]i. Using... -
The Transfection of Caldesmon DNA into Primary Cultured Rat Aortic Vascular Smooth Muscle
WoongChoiHee-YulAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 8 597-603 (7 pages)
Caldesmon (CaD), one of microfilament-associated proteins, plays a key role in microfilament assembly in mitosis. We have investigated the effects of overexpression of the high molecular weight isoform of CaD (h-CaD) on the physiology of vascular smooth muscle cells (VSMCs). Rat aortic VSMCs were stably transfected with plasmids carrying a full length human h-CaD cDNA under control of cytomegalovirus promoter. The majority of the overexpressed h-CaD appears to be localized predominantly on... -
Calcium Modulates Excitatory Amino Acid (EAA)- and Substance P-induced Rat Dorsal Horn Cell Responses
HongKeeShin, SokHanKang, InDukChung, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 5 35-45 (11 pages)
Excitatory amino acid (EAA) and substance P (SP) have been known to be primary candidates for nociceptive neurotransmitter in the spinal cord, and calcium ions are implicated in processing of the sensory informations mediated by EAA and SP in the spinal cord. In this study, we examined how Ca2 modified the responses of dorsal horn neurons to single or combined iontophoretical application of EAA and SP in the rat. All the LT cells tested responded to kainate, whereas about 55% of low... -
Protective Mechanism of Nitric Oxide and Mucus against Ischemia/ Reperfusion-Induced Gastric Mucosal Injury
HyeyoungKim, KwangsooNam, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 13 511-519 (9 pages)
This study investigated the role of nitric oxide on the oxidative damage in gastric mucosa of rats which received ischemia/reperfusion and its relation to mucus. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, and sodium nitroprusside, a nitric oxide donor, were injected intraperitoneally to the rats 30 min prior to ischemia/reperfusion which was induced by clamping the celiac artery and the superior mesenteric artery for 30 min and reperfusion for 1... -
Rapid Induction of mRNA for Prostaglandin H Synthase in Ovine Meningeal Fibroblasts
MyeongJinNam, ClaraThore, DavidBusija 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 5 435-441 (7 pages)
of protein kinase C, on mRNA for Prostaglandin H synthase (PGHS) and prostanoid production in cultured ovine meningeal fibroblasts. Immuno- and morphologically-identified fibroblasts were derived from cerebral cortex and white matter from fetal lambs (approximately 120 days gestation) and grown to confluence on glass coverslips in 12 well plates. Levels of prostaglandin F2α and the stable hydrolysis product of prostacyclin (i.e., 6-keto-PGF1α) were determined using enzyme immunoassay. Relative... -
Molecular Pharmacological Interaction of Phenylbutazone to Human Neutrophil Elastase
KooilKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 14 385-393 (9 pages)
to the human neutrophil elastase caused strong Raman shifts at 200, 440, and 1194 cm1. The peak at 1194 cm1 might be evidence of the presence of -N=N-ヶ radical. The core area of the elastase, according to the visual molecular model of human neutrophil elastase, was structurally stable. A deeply situated active center was at the core area surrounded by hydrophobic amino acids. Directly neighboring the active site was one positively charged atom and two atoms carrying a...
