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131.

Taxifolin Glycoside Blocks Human ether-a-go-go Related Gene K+ Channels

JihyunYun, HyemiBae, SunEunChoi, Jung-HaKim, YoungWookChoi6, InjaLim, ChungSooLee, MinWonLee, Jae-HongKo, SeongJunSeo, HyoweonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 6 37-42 (6 pages)

JihyunYun, HyemiBae, SunEunChoi, Jung-HaKim, YoungWookChoi6, InjaLim, ChungSooLee, MinWonLee, Jae-HongKo, SeongJunSeo, HyoweonBang 저
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- 3,000원
Taxifolin glycoside is a new drug candidate for the treatment of atopic dermatitis (AD). Many drugs cause side effects such as long QT syndrome by blocking the human ether-a-go-go related gene (hERG) K+ channels. To determine whether taxifolin glycoside would block hERG K+ channels, we recorded hERG K+ currents using a whole-cell patch clamp technique. We found that taxifolin glycoside directly blocked hERG K+ current in a concentration-dependent manner (EC50=9.6±0.7ՌM). The activation...
132.

Mechanisms of Selective Antimicrobial Activity of Gaegurin 4

HeejeongKim, ByeongJaeLee, MunHanLee, SeongGeunHong, PanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.1 7 39-48 (10 pages)

HeejeongKim, ByeongJaeLee, MunHanLee, SeongGeunHong, PanDongRyu 저
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- 3,000원
together, the present results indicate that the selectivity of GGN4 toward Gram-positive over Gram-negative bacteria is due to negative surface charges, and interaction of GGN4 with outer walls. The selectivity toward bacteria over RBC is due to the presence of phosphatidylcholine and cholesterol, and the trans-bilayer lipid asymmetry in RBC. The results suggest that design of selective antimicrobial peptides should be based on the composition and topology of membrane lipids in the target cells.
133.

The Staging of Major Mood Disorders

Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)

Ather Muneer, Rana Mazommil 저
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- 4,100원
Objective_Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods_In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like “major depressive disorder and staging,” “bipolar disorder and neuroprogression,” etc. To incorporate the latest findings the search was limited to the last 10 years. Both original and review articles were...
134.

조현병 재발방지를 위한 약물치료 전략

김지현(Jihyun Kim), 박염홍(Yanhong Piao), 신광범(Quangfan Shen), 정영철(Young-Chul Chung) 대한신경정신의학회 신경정신의학 5 Pages

대한신경정신의학회 신경정신의학 2018, 제 57권 제 3호 3 225-229 (5 pages)

김지현(Jihyun Kim), 박염홍(Yanhong Piao), 신광범(Quangfan Shen), 정영철(Young-Chul Chung) 저
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- 1,500원
135.

한국인 강박장애와 Val-158-Met Catechol-O-Methyltransferase 유전자 다형성 간의 상관성 연구

천근아, 김세주, 김찬형, 구민성, 남윤영, 박성혁, 이홍식 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 2006, 제 45권 제 5호 10 444-452 (9 pages)

천근아, 김세주, 김찬형, 구민성, 남윤영, 박성혁, 이홍식 저
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- 3,000원
136.

靑少年犯罪類型과 韓國家族形態間의 關係

金憲秀, 聞秉根, 金賢實 대한신경정신의학회 신경정신의학 20 Pages

대한신경정신의학회 신경정신의학 1996, 제 35권 제 3호 9 574-593 (20 pages)

金憲秀, 聞秉根, 金賢實 저
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- 4,900원
137.

Antifungal Activity of a Synthetic Cationic Peptide against the Plant Pathogens Colletotrichum graminicola and Three Fusarium Species

한국식물병리학회 The Plant Pathology Journal 6 Pages

한국식물병리학회 The Plant Pathology Journal 2015, 31권 3호 14 316-321 (6 pages)

저
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- 3,000원
A small cationic peptide (JH8944) was tested for activity against a number of pathogens of agricultural crops. JH8944 inhibited conidium growth in most of the tested plant pathogens with a dose of 50 μg/ml, although one isolate of Fusarium oxysporum was inhibited at 5 μg/ml of JH8944. Most conidia of Fusarium graminearum were killed within 6 hours of treatment with 50 μg/ml of JH8944. Germinating F. graminearum conidia required 238 μg/ml of JH8944 for 90% growth inhibition. The peptide did...
138.

Application of Volatile Antifungal Plant Essential Oils for Controlling Pepper Fruit Anthracnose by Colletotrichum gloeosporioides

한국식물병리학회 The Plant Pathology Journal 9 Pages

한국식물병리학회 The Plant Pathology Journal 2015, 31권 3호 8 269-277 (9 pages)

저
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- 3,000원
Anthracnose caused by Colletotrichum gloeosporioides has been destructive during pepper fruit production in outdoor fields in Korea. In vitro antifungal activities of 15 different plant essential oils or its components were evaluated during conidial germination and mycelial growth of C. gloeosporioides. In vitro conidial germination was most drastically inhibited by vapour treatments with carvacrol, cinnamon oil, trans-cinnamaldehyde, citral, p-cymene and linalool. Inhibition of the mycelial...
139.

Development of the Large-Scale Oligonucleotide Chip for the Diagnosis of Plant Viruses and its Practical Use

한국식물병리학회 The Plant Pathology Journal 7 Pages

한국식물병리학회 The Plant Pathology Journal 2014, 30권 1호 6 51-57 (7 pages)

저
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- 3,000원
A large-scale oligonucleotide (LSON) chip was developed for the detection of the plant viruses with known genetic information. The LSON chip contains two sets of 3,978 probes for 538 species of targets including plant viruses, satellite RNAs and viroids. A hundred forty thousand probes, consisting of isolate-, species- and genus-specific probes respectively, are designed from 20,000 of independent nucleotide sequence of plant viruses. Based on the economic importance, the amount of genome...
140.

Open Access ： Enhanced Biological Control of Phytophthora Blight of Pepper by Biosurfactant-Producing Pseudomonas

한국식물병리학회 The Plant Pathology Journal 9 Pages

한국식물병리학회 The Plant Pathology Journal 2013, 29권 4호 7 418-426 (9 pages)

저
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- 3,000원
Pseudomonas isolates from different crop plants were screened for in vitro growth inhibition of Phytophthora capsici and production of biosurfactant. Two in vivo experiments were performed to determine the efficacy of selected Pseudomonas strains against Phytophthora blight of pepper by comparing two fungicide treatments [acibenzolar-S-methyl (ASM) and ASM + mefenoxam]. Bacterial isolates were applied by soil drenching (1 × 109 cells/ml), ASM (0.1 μg a.i./ml) and ASM + mefenoxam...

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