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141.

Influence of Cilnidipine on Catecholamine Release in the Perfused Rat Adrenal Medulla

Seong-ChangWoo, Young-JooBaek, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.5 5 265-272 (8 pages)

Seong-ChangWoo, Young-JooBaek, Dong-YoonLim 저
...
- 3,000원
The present study was attempted to investigate the effect of cilnidipine (FRC-8635), which is a newly synthesized novel dihydropyridine (DHP) type of organic Ca2⁢ channel blockers, on secretion of catecholamines (CA) evoked by acetylcholine (ACh), high K⁢, DMPP and McN-A-343 from the isolated perfused rat adrenal gland. Cilnidipine (1∼10μM) perfused into an adrenal vein for 60 min produced relatively dose- and time-dependent inhibition in CA secretory responses evoked by ACh...
142.

Activation of Vestibular Neurons Projecting to Autonomic Brain Stem Nuclei Following Acute Hypotension in Rats

DongOkChoi, ChonIlYon, MyoungAeChoi, ByungRimPark, MinSunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 2 181-186 (6 pages)

DongOkChoi, ChonIlYon, MyoungAeChoi, ByungRimPark, MinSunKim 저
...
- 3,000원
Extracellular regulated protein kinase1/2 (pERK1/2) is one of the major regulatory factors for transcription of the c-fos oncogene in neurons. The purpose of this study was to evaluate the expression of phosphorylated ERK1/2 within the vestibular nuclei (VN) of rats following acute arterial hypotension. Following the acute arterial hypotension induced by rapid hemorrhage, a significant number of pERK1/2-immunoreactive neurons appeared bilaterally in the caudal aspect of the medial and inferior...
143.

Nitric Oxide Synthase Mediates Carbon Monoxide-Induced Stimulation of L-type Calcium Currents in Human Jejunal Smooth Muscle Cells

InjaLim, JihyunYun, SeungtaeKim, SoonchulMyung, TaehoKim, HyoweonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.3 7 161-166 (6 pages)

InjaLim, JihyunYun, SeungtaeKim, SoonchulMyung, TaehoKim, HyoweonBang 저
...
- 3,000원
Exogenous carbon monoxide (0.2%) increases L-type calcium (Ca2⁢) current in human jejunal circular smooth muscle cells. The stimulatory effect of carbon monoxide (CO) on L-type Ca2⁢ current is inhibited by pre-application of L-NNA, a classical competitive inhibitor of nitric oxide synthase (NOS) with no significant isoform selectivity (Lim, 2003). In the present study, we investigated which isoform of NOS affected CO induced stimulation of L-type Ca2⁢ current in human jejunal...
144.

Activation of Vestibular Neurons Projecting to Autonomic Brain Stem Nuclei Following Acute Hypotension in Rats

MyoungAeChoi, WonKiWang, DongOkChoi, MinSunKim, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.3 3 133-140 (8 pages)

MyoungAeChoi, WonKiWang, DongOkChoi, MinSunKim, ByungRimPark 저
...
- 3,000원
The purpose of the present study was to elucidate the possible involvement of the medial vestibular nucleus (MVN) and inferior vestibular nucleus (IVN) following acute hypotension in the vestibulo- autonomic reflex through vestibulosolitary or vestibuloventrolateral projections. Acute hypotension- induced cFos expression was assessed in combination with retrograde cholera toxin B subunit (CTb) tract tracing. After injection of CTb into the solitary region, CTb-labeled neurons were located...
145.

Carrageenan-Induced Hyperalgesia Is Partially Alleviated by Endomorphin-1 Locally Delivered into Inflamed Paws in Rat

SeoEunLeeHongKeeShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 12 369-373 (5 pages)

SeoEunLeeHongKeeShin 저
...
- 1,500원
This study was performed to test whether endomorphin-1 has analgesic effect, when locally administrated into inflamed peripheral tissue. Carrageenan suspension (0.5%) was injected intraplantarly into the right paw of Sprague-Dawley male rats, and the rats were subjected to a series of mechanical stimuli with von Frei filaments before and after the injection. Carrageenan-injected rats showed typical inflammatory hyperalgesic signs and decrease of withdrawal threshold, peaked at 3 to 6 hours after...
146.

Cooperation of Gβ and Gαq Protein in Contractile Response of Cat Lower Esophageal Sphincter (LES)

UyDongSohnTaiSangLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 9 349-355 (7 pages)

UyDongSohnTaiSangLee 저
...
- 3,000원
a CaM dependent pathway. In the esophagus ACh activates M2 receptors linked to PTX sensitive Gi3 protein, resulting in activation of PLD, presumably, production of DAG. We investigated the role of PLC isozymes which can be activated by Gq or Gβ protein on ACh-induced contraction in LES and esophagus. Immunoblot analysis showed the presence of 3 types of PLC isozymes, PLC-β1, PLC-β3, and PLC-γ1, but not PLC-β2, PLC-β4, PLC-γ2, PLC-δ1, and PLC-δ2 from both LES and esophageal muscle. ACh...
147.

Stretch-activated K+ Channels in Rat Atrial Myocytes

JaeBoumYoum 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 8 341-318 (8 pages)

JaeBoumYoum 저
...
- 3,000원
to K⁢, and the degree of activation was dependent on the magnitude of negative pressure (full activation at ∼ ⁣50 mmHg). In symmetrical 140 mM KCl, the slope conductance was 51.2⁑3 pS between the potentials of ⁣80 and 0 mV and 55⁑6 pS between 0 and ⁢80 mV (n=5). Glibenclamide (100μM) or ATP (2 mM) failed to block the channel openings, indicating that it is not ATP-sensitive K⁢ channel. Arachidonic acid (30μM), which has been shown to activate a...
148.

Mechanism of Glutamate-induced [Ca2+]i Increase in Substantia Gelatinosa Neurons of Juvenile Rats

SungJunJung, JeongSookChoi, JiyeonKwak, JunKim, JongWhanKim, SangJeongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 1 53-57 (5 pages)

SungJunJung, JeongSookChoi, JiyeonKwak, JunKim, JongWhanKim, SangJeongKim 저
...
- 1,500원
by CNQX, an AMPA receptor blocker, but not by AP-5, a NMDA receptor blocker. The glutamate-induced [Ca2⁢]i increase in Ca2⁢ free condition was not affected by iGluR blockers. A selective mGluR (group I) agonist, RS-3,5-dihydroxyphenylglycine (DHPG), induced [Ca2⁢]i increase at holding potential of ⁣70 mV in SG neurons. These findings suggest that the glutamate-induced [Ca2⁢]i increase is associated with AMPA-sensitive iGluR and group I mGluR in SG neurons of rats.
149.

Influence of Tacrine on Catecholamine Secretion in the Perfused Rat Adrenal Gland

Seok-JeongJang, Won-HoYang, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 6 207-214 (8 pages)

Seok-JeongJang, Won-HoYang, Dong-YoonLim 저
...
- 3,000원
The present study was designed to clarify whether tacrine affects the release of catecholamines (CA) from the isolated perfused model of rat adrenal gland or not and to elucidate the mechanism of its action. Tacrine (3⁓10⁣5∼3⁓10⁣4 M) perfused into an adrenal vein for 60 min inhibited CA secretory responses evoked by ACh (5.32⁓10⁣3 M), DMPP (a selective neuronal nicotinic agonist, 10⁣4 M for 2 min) and McN-A-343 (a selective muscarinic M1-agonist,...
150.

Enhanced Expression of Aldosterone Synthase and Adrenomedullin in Left and Right Ventricular Hypertrophy in Rats

JongUnLee, SungsuLee, SunmiKim, WonJungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.2 9 121-126 (6 pages)

JongUnLee, SungsuLee, SunmiKim, WonJungLee 저
...
- 3,000원
The pathophysiological implications of aldosterone and adrenomedullin in the cardiac ventricular hypertrophy were examined. Male Sprague-Dawley rats were treated with deoxycorticosterone acetate (DOCA)-salt and monocrotaline (MCT) to selectively elicit left and right ventricular (LV, RV) hypertrophy, respectively. The mRNA expression of aldosterone synthase and adrenomedullin in LV and RV was determined by reverse transcription-polymerase chain reaction. The expression of aldosterone synthase...

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