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Relative biological effectiveness of fast neutrons for apoptosis in mouse hair follicles
Hae-June Lee, Sung-Ho Kim* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 4 335-340 (6 pages)
This study compared the effects of high linear energy transfer (LET) fast neutrons on the induction of apoptosis in the hair follicles of ICR mice with those of low LET Co ■-rays. The changes that occurred from 0 to 24 h after exposing the mice to either 2 Gy of ■-rays (2 Gy/min) or 0.8 Gy of neutrons (94 mGy/min, 35 MeV) were examined. The maximum frequency was found at 12 h (■- rays) or 8 h (neutrons) after irradiation. The mice that received 0-8 Gy of ■-rays or 0-1.6 Gy of neutrons were... -
Effects of DDA, CpG-ODN, and plasmid-encoded chicken IFN-γ on protective immunity by a DNA vaccine against IBDV in chickens
Ha Jung Roh, Haan Woo Sung, Hyuk Moo Kwon 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 10 361-368 (8 pages)
This study examined the adjuvant effects of dimethyl dioctadecyl ammonium bromide (DDA), CpG oligodeoxynucleotides (CpG-ODN), and chicken interferon-γ (ChIFN-γ) on a DNA vaccine (pcDNA-VP243) against the infectious bursal disease virus (IBDV). A plasmid encoding chicken IFN-a was constructed. Twice at 2-week intervals, twoweek- old chickens were injected intramuscularly and intraperitoneally with either a DNA vaccine alone or a DNA vaccine together with the respective adjuvants. On week 2... -
In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin
Doo Kim, Dorsey Kordick, Thomas Divers, Yung-Fu Chang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 9 355-359 (5 pages)
Antimicrobial susceptibility testing was conducted with 6 different spirochetal strains (4 strains of Leptospira spp. and 2 strains of Borrelia burgdorferi) against 3 antimicrobial agents, commonly used in equine and bovine practice. The ranges of MIC and MBC of amoxicillin against Leptospira spp. were 0.05-6.25 μg/ml and 6.25-25.0 μg/ml, respectively. And the ranges of minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of amoxicillin against B. burgdorferi... -
Pharmacokinetics and bioavailability of doxycycline in ostriches (Struthio camelus) at two different dose rates
Ehab A. Abu-Basha, Nasir M. Idkaidek, Tareq M. Hantash 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 4 327-332 (6 pages)
A bioavailability and pharmacokinetics study of doxycycline was carried out on 30 healthy ostriches after a single intravenous (IV), intramuscular (IM) and oral dose of 15 mg/kg body weight. The plasma doxycycline concentration was determined by HPLC/UV at 0 (pretreatment), 0.08, 0.25, 0.5 1, 2, 4, 6, 8, 12, 24 and 48 h after administration. The plasma concentration-time curves were examined using non-compartmental methods based on the statistical moment theory for only the higher dose. After IV... -
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits
Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 10 151-155 (5 pages)
This study examined the effect of experimentally induced fever on the pharmacokinetics of cefepime (75 mg/kg BW) administered intramuscularly to six rabbits. The study was carried out in two consecutive phases separated by a two-week washout period. An infection was induced by an intravenous inoculation of 5 × 108 colony-forming units of Escherichia coli 24 h before the pharmacokinetic investigation. A quantitative microbiological assay was employed to measure the plasma cefepime concentrations... -
Changes in patterns of antimicrobial susceptibility and class 1 integron carriage among Escherichia coli isolates
Sang Gyun Kang, Deog Yong Lee, Sung Jae Shin, Jeong Min Ahn, Han Sang Yoo 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 5 201-205 (5 pages)
The worldwide use of antimicrobials in different fields has created enormous pressure for the selection of resistance among opportunistic bacterial pathogen. One hundred four E. coli isolates were collected and identified from swine with diarrhea in Korea during the period of 2002. The isolates showed highly resistant to streptomycin (99.0%), tetracycline (97.1%), neomycin (91.3%)and carbenicillin (84.6%)in antimicrobial susceptibility test. Moreover, all of the isolates showed multiple... -
Application of biotechnological tools for coccidia vaccine development
Wongi Min, Rami A. Dalloul, Hyun S. Lillehoj 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 1 279-288 (10 pages)
Coccidiosis is a ubiquitous intestinal protozoan infection of poultry seriously impairing the growth and feed utilization of infected animals. Conventional disease control strategies have relied on prophylactic medication. Due to the continual emergence of drug resistant parasites in the field and increasing incidence of broiler condemnations due to coccidia, novel approaches are urgently needed to reduce economic losses. Understanding the basic biology of host-parasite interactions and... -
Exposure to genistein does not adversely affect the reproductive system in adult male mice adapted to a soy-based commercial diet
Beom Jun Lee, Jong-Koo Kang, Eun-Yong Jung, Young Won Yun, In-Jeoung Baek, Jung-Min Yon, Yoon-Bok Lee, Heon-Soo Sohn, Jae-Yong L 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 3호 7 227-234 (8 pages)
Genistein, a soybean-originated isoflavone, is widely consumed by humans for putative beneficial health effects but its estrogenic activity may affect adversely the development of male reproductive system. Five-week-old ICR mice were purchased and fed with a soybean-based Purina Chow diet until 6 months of age. The animals were exposed by gavage to genistein (2.5 mg/kg/day) or 17β-estradiol (7.5μg/kg/day) for five weeks. Corn oil was used for the negative control. The animals were fed the... -
Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells
Jin-Hyuk Choi, Jun-Sung Kim, Young-Chul Kim, Yoon-Shin Kim, Nam-Hyun Chung and Myung-Haing Cho 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 1호 3 11-18 (8 pages)
Accurate estimation of the exposure-response relationship between ambient urban particulate matters (PM) and public health is important for regulatory perspective of ambient urban particulate matters (PM). Ambient PM contains various transition metals and organic compounds. PM10 (aerodynamic diameter less than 10 μm) is known to induce diverse diseases such as chronic cough, bronchitis, chest illness, etc. However, recent evaluation of PM2.5 (aerodynamic diameter less than 2.5 μm) against... -
Levels of lead in mineral salt commercial mixtures for beef cattle
Wilmar Sachetin Marcal, Paulo Eduardo Pardo, Marcos Roberto Lopes do Nascimento, Evandro Brandalize Veras, Aleksey Machado Moren 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 3호 6 235-238 (4 pages)
Lead concentrations was measured in samples of mineral mixtures used in beef cattle feed in the states of Sao Paulo, Parana, Mato Grosso and Mato Grosso do Sul, Brazil. Lead content was determined by inductively coupled plasma atomic emission spectrometry. Of the 60 analyzed samples, 21 had values greater than 30 ppm (range less 1.6 to 460 ppm), which is the maximum concentration recommended [3,14]. These findings show the necessity for careful industrial monitoring because some mineral mixtures...


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