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Anti-Apoptotic Effect of Rheum undulatum Water Extract in Pancreatic β-cell Line,
SeoHyunYoon, MeeSookHong, JooHoChung, SungHyunChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 8 51-55 (5 pages)
Sopungsungi-won has been used as a traditional medicine for diabetes and it has been proved to be a potential remedy for type 2 diabetes mellitus. We previously reported that water extract of Sopungsungi-won exhibits anti-diabetic effects both in vivo and in vitro experiments. In the present study, we have chosen to examined anti-apoptotic effect of Rheum undulatum, which is the main component of Sopungsungi-won, on pancreatic β-cells, HIT-T15, against hydrogen peroxide (H2O2). oxidative... -
Ca2+-activated Cl- Current in Gastric Antral Myocytes
Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 4 143-150 (8 pages)
The whole-cell mode of the patch clamp technique was used to study Ca2+-activated Cl- current (IClCa) in gastric antral myocytes. Extracellular application of caffeine evoked Ca2+-activated current. In order to isolate the chloride current from background current, all known systems were blocked with specific blockers. The current-voltage relationship of caffeine-induced current showed outward rectification and it reversed at around ECl-. The shift of reversal potential upon the alteration of...


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