학지사 뉴논문

총 498건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

151.

Glycine- and GABA-mimetic Actions of Shilajit on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Mice

HuaYin, EunJuYang, SooJoungPark, SeongKyuHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.5 6 285-290 (6 pages)

HuaYin, EunJuYang, SooJoungPark, SeongKyuHan 저
...
- 3,000원
Under the potas</SUB>sium gluconate pipette solution at holding potential 0 mV, Shilajit induced repeatable outward current. These results show that Shilajit has inhibitory effects on the SG neurons of Vc through chloride ion channels by activation of the glycine receptor and GABAA receptor, indicating that Shilajit contains sedating ingredients for the central nervous system. These results also suggest that Shilajit may be a potential target for modulating orofacial pain processing.
152.

GS28 Protects Neuronal Cell Death Induced by Hydrogen Peroxide under Glutathione-Depleted Condition

HwaOkLee, YuJeongByun, Kyung-OkCho, SeongYunKim, Seong-BeomLee, Ho-ShikKim, Oh-JooKwon, Seong-WhanJeong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 5 149-156 (8 pages)

HwaOkLee, YuJeongByun, Kyung-OkCho, SeongYunKim, Seong-BeomLee, Ho-ShikKim, Oh-JooKwon, Seong-WhanJeong 저
...
- 3,000원
Golgi SNAP receptor complex 1 (GS28) has been implicated in vesicular transport between intra-Golgi networks and between endoplasmic reticulum (ER) and Golgi. Additional role(s) of GS28 within cells have not been well characterized. We observed decreased expression of GS28 in rat ischemic hippocampus. In this study, we examined the role of GS28 and its molecular mechanisms in neuronal (SK-N-SH) cell death induced by hydrogen peroxide (H2O2). GS28 siRNA-transfected cells treated with H2O2 showed...
153.

The Relaxing Effect of α-Defensin 1 on the Adrenergic Responses of Rat Bladder

ShinYoungLee, DonKyuKim, KyungDoKim, SoonChulMyung, MooYeolLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 4 143-147 (5 pages)

ShinYoungLee, DonKyuKim, KyungDoKim, SoonChulMyung, MooYeolLee 저
...
- 1,500원
Defensins, cysteine-rich cationic polypeptides released from neutrophils, are known to have powerful antimicrobial properties. In this study, we sacrificed 30 rats to investigate the effects of Ձ-defensin 1 on detrusor muscle contractions in isolated rat bladder. From the experiments we found relaxing effects of Ձ-defensin 1 on the contractions induced by phenylephrine (PE) but not by bethanechol (BCh) in the detrusor smooth muscles. To determine the mechanisms of the effects of...
154.

Induction of the Intrinsic Apoptotic Pathway by 3-Deazaadenosine Is Mediated by BAX Activation in HL-60 Cells

Sun-YoungLee, Kyoung-WonKo, Won-KyungKang, Yun-JeongChoe, Yoon-HyoungKim, In-KyungKim, JinKim, Ho-ShikKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 9 407-412 (6 pages)

Sun-YoungLee, Kyoung-WonKo, Won-KyungKang, Yun-JeongChoe, Yoon-HyoungKim, In-KyungKim, JinKim, Ho-ShikKim 저
...
- 3,000원
and an inhibitory effect of z-VAD-Fmk on this cell death. During DZA-induced apoptosis, cytochrome c (cyt c) was released into the cytosol. This was neither prevented by z-VAD-Fmk and nor was it associated with the dissipation of mitochondrial membrane potential (ԤԸm). Prior to the release of cyt c, BAX was translocated from the cytosol to mitochondria and underwent oligomerization. Finally, the overexpression of BCL-XL protected HL-60 cells from apoptosis by blocking both the cyt c...
155.

Regional Distribution of Interstitial Cells of Cajal (ICC) in Human Stomach

Hyo-YungYun, RohyunSung, YoungChulKim, WoongChoi, HunSikKim, HeonKim, GwangJuLee, RaYoungYou, Seon-MeePark, SeiJinYun, Mi-JungKim, WonSeopK 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 11 317-324 (8 pages)

Hyo-YungYun, RohyunSung, YoungChulKim, WoongChoi, HunSikKim, HeonKim, GwangJuLee, RaYoungYou, Seon-MeePark, SeiJinYun, Mi-JungKim, WonSeopK 저
...
- 3,000원
We elucidated the distribution of interstitial cells of Cajal (ICC) in human stomach, using cryosection and c-Kit immunohistochemistry to identify c-Kit positive ICC. Before c-Kit staining, we routinely used hematoxylin and eosin (HE) staining to identify every structure of human stomach, from mucosa to longitudinal muscle. HE staining revealed that the fundus greater curvature (GC) had prominent oblique muscle layer, and c-Kit immunostaining c-Kit positive ICC cells were found to have typical...
156.

Losartan Inhibits Vascular Smooth Muscle Cell Proliferation through Activation of AMP-Activated Protein Kinase

JungEunKim, HyoungChulChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 8 299-304 (6 pages)

JungEunKim, HyoungChulChoi 저
...
- 3,000원
Losartan is a selective angiotensin II (Ang II) type 1 (AT1) receptor antagonist which inhibits vascular smooth muscle cells (VSMCs) contraction and proliferation. We hypothesized that losartan may prevent cell proliferation by activating AMP-activated protein kinase (AMPK) in VSMCs. VSMCs were treated with various concentrations of losartan. AMPK activation was measured by Western blot analysis and cell proliferation was measured by MTT assay and flowcytometry. Losartan dose- and...
157.

Tetrahydrobiopterin Inhibits PDGF-stimulated Migration and Proliferation in Rat Aortic Smooth Muscle Cells via the Nitric Oxide Synthase-independent Pathway

XiaowenJiang, BokyungKim, HaiyueLin, Chang-KwonLee, JunghwanKim, HyunKang, PilyoungLee, SeungHyoJung, HwanMyungLee, Kyung-JongWon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 10 177-183 (7 pages)

XiaowenJiang, BokyungKim, HaiyueLin, Chang-KwonLee, JunghwanKim, HyunKang, PilyoungLee, SeungHyoJung, HwanMyungLee, Kyung-JongWon 저
...
- 3,000원
Tetrahydrobiopterin (BH4), an essential cofactor for nitric oxide synthase (NOS) activity, is known to play important roles in modulating both NO and superoxide production during vascular diseases such as atherosclerosis. However, the role of BH4 in functions of vascular smooth muscle cells is not fully known. In this study, we tested the effects of BH4 and dihydrobiopterin (BH2), a BH4 precursor, on migration and proliferation in response to platelet-derived growth factor-BB (PDGF-BB) in rat...
158.

Are Spinal GABAergic Elements Related to the Manifestation of Neuropathic Pain in Rat?

JaeheeLee, SeungKeunBack, EunJeongLim, GyuChongCho, MyungAhKim, HeeJinKim, MinHeeLee, HeungSikNa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 1 59-69 (11 pages)

JaeheeLee, SeungKeunBack, EunJeongLim, GyuChongCho, MyungAhKim, HeeJinKim, MinHeeLee, HeungSikNa 저
...
- 4,000원
Impairment in spinal inhibition caused by quantitative alteration of GABAergic elements following peripheral nerve injury has been postulated to mediate neuropathic pain. In the present study, we tested whether neuropathic pain could be induced or reversed by pharmacologically modulating spinal GABAergic activity, and whether quantitative alteration of spinal GABAergic elements after peripheral nerve injury was related to the impairment of GABAergic inhibition or neuropathic pain. To these aims,...
159.

Calcium Sensitization Induced by Sodium Fluoride in Permeabilized Rat Mesenteric Arteries

EnyueYang, JoonYongCho, UyDongSohn, InKyeomKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 8 51-57 (7 pages)

EnyueYang, JoonYongCho, UyDongSohn, InKyeomKim, 저
...
- 3,000원
It was hypothesized that NaF induces calcium sensitization in Ca2＋-controlled solution in permeabilized rat mesenteric arteries. Rat mesenteric arteries were permeabilized with Ղ- escin and subjected to tension measurement. NaF potentiated the concentration-response curves to Ca2＋ (decreased EC50 and increased Emax). Cumulative addition of NaF (4.0, 8.0 and 16 mM) also increased vascular tension in Ca2＋-controlled solution at pCa 7.0 or pCa 6.5, but not at pCa 8.0. NaF-induced...
160.

MLCK and PKC Involvements via Gi and Rho A Protein in Contraction by the Electrical Field Stimulation in Feline Esophageal Smooth Muscle

SunYoungPark, JaeHoShim, MinaKim, YihHsiuSun, HyunSooKwak, XiangmeiYan, Byung-ChulChoi, ChaeukIm, SangSooSim, JiHoonJeong, InKyeomKim, Youn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 5 29-35 (7 pages)

SunYoungPark, JaeHoShim, MinaKim, YihHsiuSun, HyunSooKwak, XiangmeiYan, Byung-ChulChoi, ChaeukIm, SangSooSim, JiHoonJeong, InKyeomKim, Youn 저
...
- 3,000원
an inhibitory mediator in smooth muscle. The excitatory composition of both contractions was cholinergic dependent which was blocked by tetrodotoxin or atropine. The on-contraction was abolished in Ca2＋-free buffer but reappeared in normal Ca2＋- containing buffer indicating that the contraction was Ca2＋ dependent. 4-aminopyridine (4-AP), voltage-dependent K＋ channel blocker, significantly enhanced on-contraction. Aluminum fluoride (a G-protein activator) increased on-contraction. Pertussis...

한주간 이슈검색어