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1601.

Effects of High Glucose Levels on the Protein Kinase C Signal Transduction Pathway in Primary Cultured Renal Proximal Tubule Cells

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 8 257-268 (12 pages)

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 저
...
- 4,100원
Diabetes mellitus is associated with a wide range of pathophysiologic changes in the kidney. This study was designed to examine the mechanisms by which glucose modulates the expression of polarized membrane transport functions in primary cultured rabbit renal proximal tubule cells. Results are as follows: The rate of 30 minute Rb+ uptake was significantly higher(137.76±5.40%) in primary renal tubular cell cultures treated with 20 mM glucose than that of 5 mM glucose. Not the level of mRNA for...
1602.

Effect of Probenecid on Tetraethylammonium (TEA) Transport Across Basolateral Membrane of Rabbit Proximal Tubule

Choi, Tae-Ryong, Kim, Yong-Keun, 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 7 249-256 (8 pages)

Choi, Tae-Ryong, Kim, Yong-Keun, 저
...
- 3,000원
The effect of probenecid on the transport of tetraethylammonium (TEA) was studied in renal cortical slices and isolated membrane vesicles to investigate the interaction of organic anion with the organic cation transport system in proximal tubule. Probenecid reversibly inhibited TEA uptake by renal cortical slices in a dose-dependent manner over the concentration range of 1 and 5 mM. The efflux of TEA was not affected by the presence of 3 mM probenecid. Kinetic analysis indicated that probenecid...
1603.

Isolation and Characterization of Endosome Subpopulation in Chinese Hamster Ovarian Cells

Suh, Duk-Joon, Park, Mi-Yeon, Jung, Dong-Keun, Bae, Hae-Rahn 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 2 197-208 (12 pages)

Suh, Duk-Joon, Park, Mi-Yeon, Jung, Dong-Keun, Bae, Hae-Rahn 저
...
- 4,100원
Endosomes lower their internal pH by an ATP-driven proton pump, which is critical to dissociation of many receptor-ligand complexes, the first step in the intracellular sorting of internalized receptors and ligands. Endosomes are known to exhibit n great range of pH values that can vary between 5.0 and 7.0 within a single cell although the factors that regulate endosomal pH remain uncertain. To evaluate the morphological and topological differences of endosomes in the different stages, confocal...
1604.

Effects of Insulin and IGFs on Phosphate Uptake in Primary Cultured Rabbit Renal Proximal Tubule Cells

Han, Ho-Jae, Park, Kwon-Moo 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 7 63-76 (14 pages)

Han, Ho-Jae, Park, Kwon-Moo 저
...
- 4,300원
nmole phosphate/mg protein in the presence of 140 mM KCl during a 60 minute uptake period. Raising the concentration of extracellular phosphate to 100 mM(48.33±1.76 pmole/mg protein/min) induced decrease in phosphate uptake compared with that in control cells maintained in 1 mM phosphate(190.66±13.01 pmole/mg protein/min). Optimal phosphate uptake was observed at pH 6.5 in the presence of 140 mM NaCl. Phosphate uptake at pH 7.2 and pH 7.9 decreased to 83.06±5.75% and 74.61±3.29% of that of p...
1605.

Interaction between Renin-Angiotensin and Endothelium-Derived Nitric Oxide Systems in Two-Kidney, One Clip Hypertensive Rats

Ahn, Hyun-Tack, Nah, Kook-Joo, Lee, Jong-Un 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 4 33-42 (10 pages)

Ahn, Hyun-Tack, Nah, Kook-Joo, Lee, Jong-Un 저
...
- 3,000원
the control of renin release and to examine if NO is implicated in the development of two-kidney, one clip (2K1C) hypertension. Male Sprague-Dawley rats (150 ~ 200 g) were constricted at the left renal artery. They were then supplemented with NG-nitro-L-arginine methyl ester (L-NAME, 5mg/100 mL) or with L-arginine hydrochloride (400 mg/100 mL) in the drinking water. The control group was supplied with normal tap water. The sham-clipped rats were operated as in 2K1C rats except for that no clip...
1606.

Enhanced Efficacy of the Commissural Transmission between Lateral Giants in the Sensitization of Crayfish Escape Behavior

C.Lee, Sun-Hee 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 11 291-300 (10 pages)

C.Lee, Sun-Hee 저
...
- 3,000원
Lateral giant (LG)-mediated escape response of crayfish is sensitized by natural traumatic events. Such sensitization has previously been shown to be associated with increased transmission between primary afferents and sensory interneurons at the cholinergic synapse of LG escape reflex circuit. In the present study, it was firstly investigated as to whether transmission is also altered at other synapses of the LG-escape reflex circuit by traumatic shock-induced sensitization. Evidence that...
1607.

Inositol 1,4,5-Trisphosphate-induced Increase in Ca2+-ATPase Activity in the Microsomes of Tracheal Epithelial Cells

Cho, Hyoung-Jin, Park, Sung-Shin, Kim, Young-Kee 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 9 269-278 (10 pages)

Cho, Hyoung-Jin, Park, Sung-Shin, Kim, Young-Kee 저
...
- 3,000원
Membrane vesicles were prepared by differential centrifugation from epithelial cells of porcine trachea. Total activity of microsomal ATPases was measured spectrophotometrically by a coupled enzyme assay. The steady-state activity of the enzyme was 329±10 nmol/min mg protein. Thapsigargin, a specific antagonist of intracellular Ca2+-ATPase, inhibited about 50% of the activity, leaving 178±18 nmol/min .mg protein (n=6), indicating that the Ca2+-ATPase is one of the major microsomal ATPases....
1608.

Platelet-Activating Factor Potentiates the Activity of Respiratory Burst and Interleukin-1 in Rat Alveolar Macrophages

Lee, Ji-Hee 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 7 251-258 (8 pages)

Lee, Ji-Hee 저
...
- 3,000원
The objective of the present study was to test the effect of platelet-activating factor (PAF) on rat alveolar macrophages. PAF alone did not stimulate superoxide secretion from alveolar macrophages. However, PAF (10-5 M) significantly enhanced phagocytic activator zymosan-induced superoxide secretion from alveolar macrophages. This enhancement of PAF plus zymosan was 30% above the sum of the separate effects of PAF and zymosan. Similarly, PAF 1.3 X (10-5 M) was not a direct stimulant of...
1609.

Effects of Insulin and IGFS on Growth and Functional Differentiation in Primary Cultured Rabbit Kidney Proximal Tubule Cells -Growth and membrane transport-

Han, Ho-Jae, Park, Kwon-Moo, 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 1 191-202 (12 pages)

Han, Ho-Jae, Park, Kwon-Moo, 저
...
- 4,100원
The purpose of this study was to compare effects of insulin and IGFs on growth, apical membrane enzyme activities and membrane transport systems of primary cultured rabbit kidney proximal tubule cells. Results were as follows: 1. Insulin and IGF-I produced significant growth stimulatory effects at 5 X 10-10M. IGF-II(5 X 10 -10 M) did not stimulate significant cell growth. 2. Insulin stimulated the phosphorylation of a 97 KD protein. It was difficult to determine whether this band represents...
1610.

Effects of High Glucose on Na,K-ATPase and Na/glucose Cotransporter Activity in Primary Rabbit Kidney Proximal Tubule Cells

Han, Ho-Jae 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 7 69-80 (12 pages)

Han, Ho-Jae 저
...
- 4,100원
Renal proximal tubular hypertrophy and hyperfunction are known to be early manifestations of experimental and human diabetes. As the hypertrophy and hyperfunction have been suggested to be central components in the progression to renal failure, an understanding of their underlying causes is potentially important for the development of therapy. A primary rabbit kidney proximal tubule cell culture system was utilized to evaluate the possibility that the renal proximal tubular hypertrophy and...

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