자료유형
발행기관
- 대한생리학회-대한약리학회(171)
- 대한수의학회(56)
- 대한약리학회(29)
- 대한생리학회(26)
- 한국식물병리학회(17)
- 한국식품과학회(10)
- 한국식품영양과학회(7)
- 대한치과교정학회(6)
- 한국수산과학회(5)
- 대한신경정신의학회(4)
- 한국미생물생명공학회(4)
- 한국탄소학회(4)
- 한방비만학회(4)
- 한국수산학회(3)
- 한국기초간호학회(2)
- 한국미생물학회(2)
- 한국생명과학회(2)
- 한국생약학회(2)
- 한국약용작물학회(2)
- 고려인삼학회(1)
- 대한치과이식임플란트학회(1)
- 대한치주과학회(1)
- 한국고분자학회(1)
- 한국미용산업학회(1)
- 한국발생생물학회(1)
- 한국보건기초의학회(1)
- 한국생물공학회(1)
- 한국유가공기술과학회(1)
- 한국응용생명화학회(1)
- 한국작물학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(171)
- JOURNAL OF VETERINARY SCIENCE(39)
- 대한약리학잡지(29)
- 대한생리학회지(26)
- THE PLANT PATHOLOGY JOURNAL (14)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(12)
- 한국식품과학회지(8)
- THE KOREAN JOURNAL OF ORTHODONTICS(6)
- 대한수의학회 학술대회발표집(5)
- CARBON LETTERS(4)
- 대한한방비만학회지(4)
- 신경정신의학(4)
- 식물병연구(3)
- 한국수산과학회지(3)
- 한국수산학회지: BULLETIN OF THE KOREAN FISHERIES SOCIETY(3)
- 한국식품영양과학회지(3)
- 한국영양식량학회지(3)
- FOOD SCIENCE AND BIOTECHNOLOGY(2)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(2)
- NATURAL PRODUCT SCIENCES(2)
- 생명과학회지(2)
- 한국미생물-생명공학회지(2)
- 한국약용작물학회지(2)
- JOURNAL OF CROP SCIENCE AND BIOTECHNOLOGY(1)
- JOURNAL OF DENTAL IMPLANT RESEARCH(1)
- JOURNAL OF FISHERIES SCIENCE AND TECHNOLOGY(1)
- JOURNAL OF FOOD SCIENCE AND NUTRITION(1)
- JOURNAL OF GINSENG RESEARCH(1)
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY(1)
- KSBB JOURNAL(1)
- MACROMOLECULAR RESEARCH(1)
- THE JOURNAL OF MICROBIOLOGY(1)
- 대한치주과학회지(1)
- 미생물학회지(1)
- 미용산업연구(1)
- 발생과 생식(1)
- 산업미생물학회지(1)
- 한국농화학회지(1)
- 한국보건기초의학회지(1)
- 한국양식학회지(1)
- 한국유가공기술과학회지(1)
전체 선택해제
총 367건 검색
본문검색 결과만 보기
-
Effect of Defibrotide on Rat Reflux Esophagitis
HyoungKiKim, SooRanChoi, SangJinChoi, MyungSupChio, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 5 319-328 (10 pages)
This study was aimed at evaluating the effect of defibrotide on the development of the surgically induced reflux esophagitis, on gastric secretion, lipid peroxidation, polymorphonuclear leukocytes (PMNs) accumulation, polymorphonuclear leukocytes adherence, superoxide anion and hydrogen peroxide production in PMNs, scavenge of hydroxyl radical and hydrogen peroxide, cytokine (interleukin-1β, tumor necrosis factor-α) production in blood, and intracellular calcium mobilization in PMNs.... -
Vibrio vulnificus Cytolysin Forms Anion-selective Pores on the CPAE Cells, a Pulmonary Endothelial Cell Line
Bok-HeeChoi, Byung-HyunPark, Yong-GeunKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.5 4 259-264 (6 pages)
Cytolysin produced by Vibrio vulnificus has been incriminated as one of the important virulence determinants in V. vulnificus infection. Ion selectivity of cytolysin-induced pores was examined in a CPAE cell, a cell line of pulmonary endothelial cell, using inside-out patch clamp techniques. In symmetrical NaCl concentration (140 mM), intracellular or extracellular application of cytolysin formed ion-permeable pores with a single channel conductance of 37.5⁑4.0 pS. The pore currents were... -
The Effect of Ghrelin on Ca2+ Concentration in Thyroid FRTL-5 Cells
ByungJooKim, YoungJooPark, DoJoonPark, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 4 195-200 (6 pages)
Ghrelin is a newly discovered peptide, which is released from the stomach and neurons in the hypothalamic arcuate nucleus (ARC), and potently stimulates growth hormone release and food intake. In the present study, we investigated the effect of ghrelin on [Ca2]i in thyroid FRTL-5 cells. Ghrelin (5 nM) increased [Ca2]i and TSH (1 unit/l) had an additive effect on [Ca2]i when extracellular normal solution was 1.1mM Ca2 containing Coon's modified Ham's F12 medium. When... -
PGE2 Regulates Pacemaker Currents through EP2-Receptor in Cultured Interstitial Cells of Cajal from Murine Small Intestine
SeokChoi, KyungWonCho, Jong-HyunReu, Jun-SooKim, HyunSikMun, MyungYoungKim, KwangChulPark, GwangSikHeo, SungJongChang, CheolHoYeum, PyungJ 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.3 6 153-160 (8 pages)
The interstitial cells of Cajal (ICCs) are the pacemaker cells in gastrointestinal tract and generate electrical rhythmicity in gastrointestinal muscles. Therefore, ICC may be modulated by endogenous agents such as neurotransmitter, hormones, and prostaglandins (PGs). In the present study, we investigated the effects of prostaglandins, especially PGE2, on pacemaker currents in cultured ICCs from murine small intestine by using whole-cell patch clamp techniques. ICCs generated spontaneous slow... -
Cooperation of Gβ and Gαq Protein in Contractile Response of Cat Lower Esophageal Sphincter (LES)
UyDongSohnTaiSangLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 9 349-355 (7 pages)
We previously shown that LES contraction depends on M3 receptors linked to PTX insensitive Gq protein and activation of PLC. This results in production of IP3, which mediates calcium release, and contraction through a CaM dependent pathway. In the esophagus ACh activates M2 receptors linked to PTX sensitive Gi3 protein, resulting in activation of PLD, presumably, production of DAG. We investigated the role of PLC isozymes which can be activated by Gq or Gβ protein on ACh-induced contraction in... -
Involvement of Oxidative Stress and Poly(ADP-ribose) Polymerase Activation in 3-Nitropropionic Acid-induced Cytotoxicity in Human Neuroblastoma Cells
EunjooNam, YoungJaeLee, YoungAhOh, JinAhJung, HyeInIm, SeongEunKoh, SunghoMaeng, WanSeokJoo, YongSikKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 6 325-331 (7 pages)
3-Nitropropionic acid (3-NP) inhibits electron transport in mitochondria, leading to a metabolic failure. In order to elucidate the mechanism underlying this toxicity, we examined a few biochemical changes possibly involved in the process, such as metabolic inhibition, generation of reactive oxygen species (ROS), DNA strand breakage, and activation of Poly(ADP-ribose) polymerase (PARP). Exposure of SK-N-BE(2)C neuroblastoma cells to 3-NP for 48 h caused actual cell death, while inhibition of... -
Selective Cytotoxicity of Novel Platinum(II) Coordination Complexes on Human Bladder Cancer Cell-Lines and Normal Kidney Cells
Jung-TaeKim, Young-SooRho, Jee-ChangJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 10 111-117 (7 pages)
the aim of reducing nephrotoxicity but maintaining its anticancer activity. In this study, new platinum(II) complex compounds were evaluated for selective cytotoxicity on cancer cell-lines and normal kidney cells. The new platinum complexes have demonstrated high efficacy in the cytotoxicity against human bladder carcinoma cell-lines (T-24/HT-1376). The cytotoxicity of these compounds against rabbit proximal renal tubular cells and human renal cortical tissues, was determined by MTT assay, the... -
Effects of Noradrenaline on the Membrane Potential of Prostatic Neuroendocrine Cells of Rat
JunHeeKim, SunYoungShin, Dae-YongUhm, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.1 9 47-52 (6 pages)
The prostate gland contains numerous neuroendocrine cells that are believed to influence the function of the prostate gland. Our recent study demonstrated the expression of both α1- and α2-ARs, signaling the release of stored Ca2 and the inhibition of N-type Ca2 channels, respectively, in rat prostate neuroendocrine cells (RPNECs). In this study, the effects of NA on the resting membrane potential (RMP) of RPNECs were investigated using a whole-cell patch clamp method. Fresh... -
Altered Secretory Pattern of Pancreatic Enzymes and Gastrointestinal Hormones in Streptozotocin-induced Diabetic Rats
Myung-JunKim, GyeongRyulRyu, Sae-YoungYi, DoSikMin, Duck-JooRhie, ShinHeeYoon, SangJuneHahn, Myung-SukKim, Yang-HyeokJo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 6 311-317 (7 pages)
This study was performed to investigate the pancreatic exocrine dysfunction in streptozotocin- induced diabetic rats. Changes in pancreatic enzymes secretion and in pancreatic enzymes content were observed. The output and the tissue content of amylase were significantly reduced in diabetic rats, while the output and the content of lipase were increased. Plasma secretin and cholecystokinin (CCK) concentrations of diabetic rats were significantly increased compared to those of normal rats. The... -
Characterization of Intermediate Conductance K+ Channels in Submandibular Gland Acinar Cells
Sung-ManCho, ZhengGenPiao, YoonBaeKim, Joong-SooKim, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 5 305-309 (5 pages)
we increased Ca2 concentration of the bath solution in inside-out mode, the IK channel activity was greatly increased, suggesting this channel is Ca2 sensitive. We next examined the effect of carbachol (CCh) and isoproterenol on the activity of the IK channels. 105 M isoproterenol significantly increased the open probability (Po) from 0.08⁑0.02 to 0.21⁑0.03 (n=4, P＜0.05). Application of 105 M CCh also increased Po from 0.048⁑0.03 to 0.55⁑0.33...
