발행기관
- 대한생리학회-대한약리학회(15)
- 대한약리학회(15)
- 대한생리학회(14)
- 한국탄소학회(10)
- 한국열환경공학회(6)
- 대한신경정신의학회(5)
- 대한기계학회(3)
- 대한전자공학회(3)
- 한국식물병리학회(3)
- 한국액체미립화학회(2)
- 대한설비공학회(1)
- 한국분석과학회(1)
- 한국세라믹학회(1)
- 한국수산학회(1)
- 한국연소학회(1)
- 한국유화학회(1)
- 한국자기학회(1)
- 한국자원리싸이클링학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(15)
- 대한약리학잡지(15)
- 대한생리학회지(14)
- CARBON LETTERS(10)
- 신경정신의학(5)
- 열환경공학(4)
- 전자공학회논문지. JOURNAL OF THE INSTITUTE OF ELECTRONICS ENGINEERS OF KOREA. SD, 반도체(3)
- THE PLANT PATHOLOGY JOURNAL (2)
- 대한기계학회론문집. TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS. B. B(2)
- 한국액체미립화학회지(2)
- 한국열환경공학회 학술대회지(2)
- 대한기계학회론문집. TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS. A. A(1)
- 분석과학(1)
- 설비공학논문집(1)
- 식물병연구(1)
- 요업학회지(1)
- 자원리싸이클링 : 한국자원리싸이클링학회지(1)
- 한국수산학회지: BULLETIN OF THE KOREAN FISHERIES SOCIETY(1)
- 한국연소학회지(1)
- 한국유화학회지(1)
- 한국자기학회지(1)
전체 선택해제
총 84건 검색
본문검색 결과만 보기
-
Cisplatin-induced Alterations of Na+-dependent Phosphate Uptake in Renal Epithelial Cells
SungJuLee, ChaeHwaKwon, YongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.2 5 71-77 (7 pages)
Cisplatin treatment increases the excretion of inorganic phosphate in vivo. However, the mechanism by which cisplatin reduces phosphate uptake through renal proximal tubular cells has not yet been elucidated. We examined the effect of cisplatin on Na-dependent phosphate uptake in opossum kidney (OK) cells, an established proximal tubular cell line. Cells were exposed to cisplatin for an appropriate time period and phosphate uptake was measured using [32P]-phosphate. Changes in the number... -
Reduction of Muscarinic K+ Channel Activity by Transferrin in Ischemic Rat Atrial Myocytes
KyeongTaePark, DawonKang, JaeheeHan, Jae-YongPark, Chang-GiHur, Seong-GeunHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 7 333-339 (7 pages)
It has been demonstrated that an unidentified cytosolic factor(s) reduces KACh channel function. Therefore, this study attempted to elucidate the cytosolic factor. Fresh cytosol isolated from normal heart (FC) depressed the KACh channel activity, but cytosol isolated from the ischemic hearts (IC) did not modulate the channel function. Electrophorectic analysis revealed that a protein of ∼80 kDa was markedly reduced or even lost in IC. By using peptide sequencing analysis and Western blot, this... -
Comparative Effects of PKB-α and PKC-ζ on the Phosphorylation of GLUT4-Containing Vesicles in Rat Adipocytes
Jong-SikHah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 7 479-486 (8 pages)
Insulin stimulates glucose transport in muscle and fat cells by promoting the translocation of glucose transporter (GLUT4) to the cell surface. Phosphatidylinositide 3-kinase (PI3-kinase) has been implicated in this process. However, the involvement of protein kinase B (PKB)/Akt and PKC-ζ, those are known as the downstream target of PI3-kinase in regulation of GLUT4 translocation, is not known yet. An interesting possibility is that these protein kinases phosphorylate GLUT4 directly in this... -
Different Effects of Dopamine on Differential Rotational Mobility between Inner and Outer Monolayer of Synaptosomal Plasma Membrane Vesicles Isolated from Bovine Brain
Hyun-GangKim, Chang-HwaChoi, Inn-SeKim, In-KyoChung, Goon-JaeCho, Hye-OckJang6, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 10 409-415 (7 pages)
Fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) was used to evaluate the effects of dopamine·HCl on the range of the rotatioanl mobility of bulk bilayer structure of the synaptosomal plasma membrane vesicles (SPMV) isolated from whole bovine brain. In a dose-dependent manner, dopamine decreased the anisotropy (γ), limiting anisotropy (γ∞) and order parameter (S) of DPH in the membranes. These indicate that dopamine increased the rotational mobility of the probe in the... -
Further Characterization of Bombesin Like Immunoreactivities from the Skin of Korean Fire-bellied Toad, Bombina orientalis
HyeokYilKwon, HyungSeoPark, MooHoWon, YunLyulLee, HyoungJinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 12 637-644 (8 pages)
Previously, we have isolated authentic bombesin and another bombesin like peptide named bombesin like immunoreactivity (BLI)-K2 from the skin of Korean fire-bellied toad, Bombina orientalis. In the present study, we have newly purified three heterogeneous forms of BLI named BLI-K3, BLI-K4, and BLI-K5 from side fractions obtained in previous isolation of bombesin like peptide. The BLIs were separated into five peaks on a column of C18 preparative HPLC. Among them, three minor peaks containing... -
Effect of the Inhibition of Platelet Activating Factor on Oxidative Lung Injury Induced by Interleukin-1α
YoungManLeeYoon-YubPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 10 479-491 (13 pages)
In order to know the pathogenesis of adult respiratory distress syndrome (ARDS) in association with the oxidative stress by neutrophils, the role of platelet activating factor (1-0-alkyl-2-acetyl-sn- glycero-3-phosphocholine, PAF) was investigated during acute lung injury induced by interleukin- 1α (IL-1) in rats. An insufflation of IL-1 into the rat's trachea increased the acetyltransferase activity in the lung and the increase of PAF content was followed. As evidences of acute lung injury by... -
[3H]Ryanodine Binding Sites of SR Vesicles of the Chicken Pectoral Muscle
Hyo-YungYun, Jong-RyeJeon, Jang-HeeHong, Gang-MinHur, Jae-HeunLee, Jeong-HoSeok* 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 4 377-384 (8 pages)
chicken pectoral muscle. The chicken SR vesicles have two high molecular weight (HMW) protein bands as in eel SR vesicles on SDS PAGE. The HMW bands on SDS PAGE were found in the [3H] ryanodine peak fraction (Fr3-5) obtained from the purification step of the ryanodine receptor protein. Bmax and KD of the chicken [3H]ryanodine binding sites were 12.52 pmol/mg protein and 14.53 nM, respectively. Specific [3H]ryanodine binding was almost maximal at 50∼100 ՌM Ca2+, but was not increased by 5... -
자폐아동에서 FMR-1 유전자에 대한 분자유전학적 연구
강경미, 곽동일, 이민수 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 6호 26 1479-1487 (9 pages)
연구목적： 자폐장애가 유전성이 있다고 제시하는 많은 쌍생아 및 가족연구와 유전자 연구에도 불구하고 이 질환의 유전 방식과 관련 유전자는 현재까지 알려져 있지 않고, 이 장애는 임상적으로 이질적 장애이며 유전적으로도 다 인자 질환일 가능성이 높은 것으로 생각된다. 본 연구에서는 자폐장애와 FMR-1 유전자간의 연관성을 조사 하고자 자폐장애 아동 총 66명을 대상으로 분자유전학적 검사를 시행하였다. 방 법： 연구대상군은 DSM-Ⅳ 진단기준으로 자폐장애에 해당하고 K-CARS 점수가 30점 이상인 아동들을 대상으 로 하였다.... -
Chlorpromazine의 유전적 안전성에 관한 연구
김한규, 손윤희, 이광헌, 윤태호, 남경수 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 3호 14 629-637 (9 pages)
연구목적： 항 정신성약물로 사용빈도가 높은 chlorpromazine을 사용하여 이 약물의 돌연변이원성과 유전독성을 알 아보았다. 방 법： Bacillus subtilis을 사용한 DNA손상성검토(rec assay), Salmonella typhimurium을 이용한 돌연변이원 성실험(Ames test 및 SOS umu test) 그리고 생쥐에 chlorpromazine를 직접 주입하여 대사 후에 돌연변이 원성을 확인하는 host-mediated assay법을 각각 사용하였다. 결 과： Rec assay에서 chlorpromazine은 Bacillus subtilis의 DNA에는 별다른 영향을 미치지 않았으며, Salmonella typhomurium TA...
