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d-Amphetamine이 백서뇌의 5-HT, 5-HIAA, MAO 및 행동에 미치는 영향에 관한 연구
서유헌(Yoo Hun Suh), 우종인(Jong In Woo)박찬웅(Chan Woong Park) 대한약리학회 대한약리학잡지 16 Pages
대한약리학회 대한약리학잡지 1981, 제 17권 제 2호 6 47-62 (16 pages)
d-amphetamine이 사람에서 paranoid schizophrenia와 아주 유사한 model psychosis를 일으키며 또한 사람과 실험동물에서 실제 정신분열증에서 뚜렷이 관찰되는 behavioral perservation을 일으킬 수 있음이 관찰되었다. 이에 많은 학자들은 이러한 양상의 행동변화가 정신분열증의 원인 추구에 중요한 의미를 주는 뇌변화를 반영할지도 모른다는 생각에 많은 연구를 거듭하여 왔다. 지금까지는 주로 catecholamine기전에 대하여 집중적 연구가 수행되어져 왔으나 최근에는 d-amphetamine의 약리기전의 일부는 5-HT기전이 차지하고... -
Multilevel Multiple-Group Latent Profile Analysis of Instructional Practices in Science: Cross-national Comparison between Korea and Japan
Son Yoonhee, Hong Yujung, Park Hyun-Jeong, Kim Junok 한국교육학회 교육학연구 30 Pages
한국교육학회 교육학연구 2021, 59권 7호 3 55-84 (30 pages)
This study aims to extend the multi-group latent profile approach proposed by Morin et al. (2016) to a multilevel context and to provide an illustration with real-world data. Specifically, multilevel multiple-group latent profile analysis (MMLPA) models were fitted following seven steps to classify students according to their perception of instructional practices in science classrooms and to compare the latent profiles of two countries using Korean and Japanese data from the Programme for... -
Cyanidin-3-glucoside Inhibits ATP-induced Intracellular Free Ca2+ Concentration, ROS Formation and Mitochondrial Depolarization in PC12 Cells
ShaziaPerveen, JiSeonYang, TaeJoungHa, ShinHeeYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.4 3 297-305 (9 pages)
Flavonoids have an ability to suppress various ion channels. We determined whether one of flavonoids, cyanidin-3-glucoside, affects adenosine 5'-triphosphate (ATP)-induced calcium signaling using digital imaging methods for intracellular free Ca2+ concentration ([Ca2+]i), reactive oxygen species (ROS) and mitochondrial membrane potential in PC12 cells. Treatment with ATP (100μM) for 90 sec induced [Ca2+]i increases in PC12 cells. Pretreatment with cyanidin-3-glucoside (1μg/ml to 100μg/ml)... -
Effects of Fluvastatin on the Pharmacokinetics of Repaglinide: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Fluvastatin
Chong-KiLee, Jun-ShikChoi, JoonSeokBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 10 245-251 (7 pages)
The purpose of this study was to investigate the effects of fluvastatin on the pharmacokinetics of repaglinide in rats. The effect of fluvastatin on P-glycoprotein and CYP3A4 activity was evaluated. The pharmacokinetic parameters and blood glucose concentrations were also determined after oral and intravenous administration of repaglinide to rats in the presence and absence of fluvastatin. Fluvastatin inhibited CYP3A4 activity in a concentration-dependent manner with a 50% inhibition... -
Quercetin Inhibits α3β4 Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes
Byung-HwanLee, Sung-HeeHwang, Sun-HyeChoi, Tae-JoonShin, JiyeonKang, Sang-MokLee, Seung-YeolNah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.1 3 17-22 (6 pages)
Quercetin mainly exists in the skin of colored fruits and vegetables as one of flavonoids. Recent studies show that quercetin, like other flavonoids, has diverse pharmacological actions. However, relatively little is known about quercetin effects in the regulations of ligand-gated ion channels. In the previous reports, we have shown that quercetin regulates subsets of homomeric ligand-gated ion channels such as glycine, 5-HT3A and Ձ7 nicotinic acetylcholine receptors. In the present study,... -
상수 공정 시간을 갖는 라인 생산 시스템에서 DBR과 CONWIP의 성능 비교 분석
이호창, 서동원, Lee. Hochang, Seo. Dong-Won 한국시뮬레이션학회 한국시뮬레이션학회논문지 14 Pages
한국시뮬레이션학회 한국시뮬레이션학회논문지 2012, Vol.21 No.4 11-24 (14 pages)
max-plus 선형시스템의 특수형태임을 밝히고 max-plus 대수에 기반한 안정대기시간 연구결과를 이용하여 CONWIP와 DBR의 성능을 비교 분석하였다. CONWIP의 경우, 생산시스템 내의 체류시간은 DBR의 경우보다 항상 짧다는 사실이 수학적으로 규명되었고 예제를 통해 계산, 비교되었다. 한편 두 경우에서 모두, 애로공정이후 노드에서의 대기시간은 유한버퍼의 크기와 공정의 순서에 무관함을 확인하였다. CONWIP에서는 시스템 내 평균 대기시간 또는 체류시간이 공정의 순서에 무관하지만, DBR에서는 애로공정이 뒤로 갈수록 감소함을... -
Effect of Ethanol on Na+-Pi Uptake in Opossum Kidney Cells Role of Membrane Fluidization and Reactive Oxygen Species
InHoPark, MoonYoungHwang, JaeSukWoo, JinSupJung, YongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 10 529-538 (10 pages)
scavengers did not alter the ethanol effect. A potent antioxidant DPPD and iron chelators did not prevent the inhibition. Pyrazole, an inhibitor of alcohol dehydrogenase, did not attenuate ethanol-induced inhibition of Na-Pi uptake, but it prevented ethanol-induced cell death. These results suggest that ethanol may inhibit Na-Pi uptake through a direct action on the carrier protein, although the transport system is affected by alterations in the lipid environment of the membrane. -
Immunochemical Studies for the Characterization of Purified(Na+, K+)-ATPase and Its Subunits with a Special Reference of Their Effect on Monovalent Cation Transport in Reconstituted (Na+, K+)-ATPase Vesicles
Rhee H.M., Hokin, L.E. 대한약리학회 대한약리학잡지 16 Pages
대한약리학회 대한약리학잡지 1990, 제 26권 제 1호 5 35-50 (16 pages)
the enzymatic activity of (Na+, K+)-ATPase molecules incorporated in the vesicles. These findings that the inhibitory effects of the antibodies specific to (Na+, K+)-ATPase or to its subunits on ATP and temperature sensitive monovalent cation transport in parallel with the inhibitory effect of vesicular catalytic activity by these antibodies provide direct evidence that (Na+, K+)-ATPase is the molecular machinery of active cation transport in this reconstituted (Na+, K+)-ATPase vesicular system. -
MBCAST: A Forecast Model for Marssonina Blotch of Apple in Korea
Hyo-suk Kim, Jung-hee Jo, Wee Soo Kang, Yun Su Do, Dong Hyuk Lee, Mun-Il Ahn, Joo Hyeon Park, Eun Woo Park 한국식물병리학회 The Plant Pathology Journal 13 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 6호 5 585-597 (13 pages)
A disease forecast model for Marssonina blotch of apple was developed based on field observations on airborne spore catches, weather conditions, and disease incidence in 2013 and 2015. The model consisted of the airborne spore model (ASM) and the daily infection rate model (IRM). It was found that more than 80% of airborne spore catches for the experiment period was made during the spore liberation period (SLP), which is the period of days of a rain event plus the following 2 days. Of 13... -
Morphological and Molecular Characterization of Heterodera schachtii and the Newly Recorded Cyst Nematode, H. trifolii Associated with Chinese Cabbage in Korea
Abraham Okki Mwamula, Hyoung-Rai Ko, Youngjoon Kim, Young Ho Kim, Jae-Kook Lee, Dong Woon Lee 한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 4호 4 297-307 (11 pages)
The sugar beet cyst nematode, Heterodera schachtii is a well known pathogen on Chinese cabbage in the highland fields of Korea. However, a race of cyst forming nematode with close morphological resemblance to H. trifolii was recently isolated from the same Chinese cabbage fields. Morphological species differentiation between the two cyst nematodes is challenging, with only minor differences between them. Thus, this study described the newly intercepted H. trifolii population, and reviewed...


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