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191.

(? )-Epigallocatechin Gallate Inhibits the Pacemaker Activity of Interstitial Cells of Cajal of Mouse Small Intestine

KweonYoungKim, SooJinChoi, HyukJinJang, DongChuanZuo, PawanKumarShahi, ShankarPrasadParajuli, CheolHoYeum, PyungJinYoon, SeokChoi, JaeYeo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.3 4 111-116 (6 pages)

KweonYoungKim, SooJinChoi, HyukJinJang, DongChuanZuo, PawanKumarShahi, ShankarPrasadParajuli, CheolHoYeum, PyungJinYoon, SeokChoi, JaeYeo 저
...
- 3,000원
The effects of (−)-epigallocatechin gallate (EGCG) on pacemaker activities of cultured interstitial cells of Cajal (ICC) from murine small intestine were investigated using whole-cell patch-clamp technique at 30oC and Ca2＋ image analysis. ICC generated spontaneous pacemaker currents at a holding potential of −70 mV. The treatment of ICC with EGCG resulted in a dose-dependent decrease in the frequency and amplitude of pacemaker currents. SQ-22536, an adenylate cyclase inhibitor, and...
192.

Relaxant Effect of Spermidine on Acethylcholine and High K+- induced Gastric Contractions of Guinea-Pig

YoungChulKim, JaeHoonSim, Woong-Choi, ChanHyungKim, Ra-YoungYou, Wen-XieXu, SangJinLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.2 4 59-64 (6 pages)

YoungChulKim, JaeHoonSim, Woong-Choi, ChanHyungKim, Ra-YoungYou, Wen-XieXu, SangJinLee 저
...
- 3,000원
on mechanical contractions and calcium channel current (IBa), and then compared its effects to those by spermine and putrescine. Spermidine inhibited spontaneous contraction of the gastric smooth muscle in a concentration-dependent manner (IC50=1.1±0.11 mM). Relationship between inhibition of contraction and calcium current by spermidine was studied using 50 mM high K+-induced contraction: Spermidine (5 mM) significantly reduced high K+ (50 mM)-induced contraction to 37±4.7% of the control...
193.

Effects of Apigenin on Glutamate-induced [Ca2+]i Increases in Cultured Rat Hippocampal Neurons

Ji-HwaHan, KiJungKim, Hyun-JongJang, JuHoJang, Myung-JunKim, KiWugSung, Duck-JooRhie, Yang-HyeokJo, SangJuneHahn, Mun-YongLee, ShinHeeYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.2 2 43-50 (8 pages)

Ji-HwaHan, KiJungKim, Hyun-JongJang, JuHoJang, Myung-JunKim, KiWugSung, Duck-JooRhie, Yang-HyeokJo, SangJuneHahn, Mun-YongLee, ShinHeeYoon 저
...
- 3,000원
min), and significantly inhibited the AMPA-induced peak currents. Treatment with apigenin also significantly inhibited the [Ca2+]i response induced by 50 mM KCl solution, decreased the [Ca2+]i responses induced by the metabotropic glutamate receptor agonist, (S)-3,5-dihydroxy</SUB>phenylglycine (DHPG, 100ՌM, 90 s), and inhibited the caffeine (10 mM, 2 min)-induced [Ca2+]i responses. Furthermore, treatment with apigenin (30ՌM) significantly inhibited the amplitude and frequency...
194.

Roles of Dopaminergic D1 and D2 Receptors in Catecholamine Release from the Rat Adrenal Medulla

YoungJooBaek, YooSeongSeo, DongYoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.1 3 13-24 (12 pages)

YoungJooBaek, YooSeongSeo, DongYoonLim 저
...
- 4,100원
The aim of the present study was designed to establish comparatively the inhibitory effects of D1-like and D2-like dopaminergic receptor agonists, SKF81297 and R(-)-TNPA on the release of catecholamines (CA) evoked by cholinergic stimulation and membrane depolarization from the isolated perfused model of the rat adrenal medulla. SKF81297 (30ՌM) and R-(-)-TNPA (30ՌM) perfused into an adrenal vein for 60 min, produced great inhibition in the CA secretory responses evoked by ACh...
195.

Involvement of Endoplasmic Reticulum Stress Response in the Neuronal Differentiation

YoonMiCho, YoonSeongJang, Young-MinJang, Jin-YoungSeo, HoShikKim, JeongHwaLee, SeongWhanJeong, InKyungKim, Oh-JooKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.6 2 239-248 (10 pages)

YoonMiCho, YoonSeongJang, Young-MinJang, Jin-YoungSeo, HoShikKim, JeongHwaLee, SeongWhanJeong, InKyungKim, Oh-JooKwon 저
...
- 3,000원
Expressions of endoplasmic reticulum stress response (ERSR) genes were examined during the neuronal differentiation of rat fetal cortical precursor cells (rCPC) and rat pheochromocytoma PC12 cells. When rCPC were differentiated into neuronal cells for 7 days, early stem cell marker, nestin, expression was decreased from day 4, and neuronal markers such as neurofilament-L, -M and Tuj1 were increased after day 4. In this condition, expressions of BIP, ATF6, and phosphorylated PERK as well as their...
196.

Inhibition of the Desensitization of Canonical Transient Receptor Potential Channel 5 by Dimethyl Sulfoxide

ByungJooKim, InsukSo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 10 227-231 (5 pages)

ByungJooKim, InsukSo 저
...
- 1,500원
the rate of this desensitization. Under the control conditions, TRPC5 current spontaneously declined to 6±1% of the initial peak amplitude 60 sec after CCh application and to 1±0.5% after 120 sec. But, in the presence of 0.01%, 0.1% and 1% DMSO, TRPC5 current spontaneously declined to 55±2%, 68±1% and 100±0.2% of the initial peak amplitude 60 sec after CCh application and to 38±2%, 61±1% and 100±1% after 120 sec, respectively. The results suggest that DMSO can internally attenuate the...
197.

Ca2+-dependent Long-term Inactivation of Cardiac Na+/Ca2+ Exchanger

Jee-EunLee, TongMookKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 4 183-188 (6 pages)

Jee-EunLee, TongMookKang 저
...
- 3,000원
Using BHK cells with stable expression of cardiac Na+/Ca2+ exchanger (BHK-NCX1), reverse mode (i.e. Ca2+ influx mode) of NCX1 current was recorded by whole-cell patch clamp. Repeated stimulation of reverse NCX1 produced a cytosolic Ca2+-dependent long-term inactivation of the exchanger activity. The degrees of inactivation correlated with NCX1 densities of the cells and were attenuated by reduced Ca2+ influx via the reverse exchanger. The inactivation of NCX1 was attenuated by (i) inhibition of...
198.

Effects of R. Glutinosa and E. Senticosus on Postmenopausal Osteoporosis

SooYeonOh, DipendraKumarAryal, Yoon-GyoonKim, , Hyung-GunKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 7 121-127 (7 pages)

SooYeonOh, DipendraKumarAryal, Yoon-GyoonKim, , Hyung-GunKim, 저
...
- 3,000원
In this study, we investigated the therapeutic effects of a novel formulation of low-dose calcium and vitamin D3, blended with Rehmannia glutinosa Libosch and Eleutherococcus senticosus Max (RE⁢), in postmenopausal women. The controls were given either a placebo or high dose calcium and vitamin D3 (Ca⁢D). Bone mineral density (BMD) in the L2-3 lumber spines and femur regions was assessed, and serum osteocalcin, bone-specific alkaline phosphatase (BALP), and cross-linked N-telopeptide...
199.

Influence of Nicorandil on Catecholamine Release in the Perfused Rat Adrenal Medulla

Young-YoupKoh, Eun-SookLee, Hae-JeongNo, , Seong-ChangWoo, Joong-WhaChung, Yoo-SeungSeoh, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 4 97-106 (10 pages)

Young-YoupKoh, Eun-SookLee, Hae-JeongNo, , Seong-ChangWoo, Joong-WhaChung, Yoo-SeungSeoh, Dong-YoonLim 저
...
- 3,000원
The present study was attempted to investigate the effect of nicorandil, which is an ATP-sensitive potassium (KATP) channel opener, on secretion of catecholamines (CA) evoked by cholinergic stimulation and membrane depolarization from the isolated perfused rat adrenal glands. The perfusion of nicorandil (0.3∼3.0 mM) into an adrenal vein for 90 min produced relatively dose-and time-dependent inhibition in CA secretion evoked by ACh (5.32 mM), high K+ (a direct membrane depolarizer, 56 mM), DMPP...
200.

Tetanus-induced LTD of Developing MNTB-LSO Synapses in Rat is Dependent on Postsynaptic Ca2+

SeungCheolAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 1 79-84 (6 pages)

SeungCheolAhn 저
...
- 3,000원
2 min) in the current clamp mode induced a robust LTD of isolated D, L-APV-sensitive postsynaptic currents (PSCs) for more than 30 min (n=6, 2.4⁑0.4% of the control), while isolated CNQX-sensitive PSCs were not suppressed (n=6, 95.3⁑1.6%). Tetanus also elicited similar LTD in the isolated GABAergic/glycinergic PSCs (n=5, 3.6⁑0.5%) and mixed PSCs (GABAergic/glycinergic/glutamatergic) (n=4, 2.2⁑0.7%). However, such a strong LTD was not observed in the mixed PSCs when 10 mM...

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