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Effect of Agrimonia pilosa Ledeb Extract on the Antinociception and Mechanisms in Mouse
Soo-HyunPark, Yun-BeomSim, Yu-JungKang, Jin-KooLee, Soon-SungLim, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 6 119-123 (5 pages)
writhing test. However, naloxone (opioid receptor antagonist) or methysergide (5-HT serotonergic receptor antagonist) did not affect antinociception induced by Agrimonia pilosa Ledeb extract in the writhing test. Our results suggest that Agrimonia pilosa Ledeb extract shows an antinociceptive property in various pain models. Furthermore, this antinociceptive effect of Agrimonia pilosa Ledeb extract may be mediated by Ձ2-adrenergic receptor, but not opioidergic and serotonergic receptors. -
Modern Methods for Analysis of Antiepileptic Drugs in the Biological Fluids for Pharmacokinetics, Bioequivalence and Therapeutic Drug Monitoring
JuseopKang, Yoo-SinPark, Shin-HeeKim, Sang-HyunKim, Min-YoungJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 1 67-82 (16 pages)
Epilepsy is a chronic disease occurring in approximately 1.0% of the world's population. About 30% of the epileptic patients treated with availably antiepileptic drugs (AEDs) continue to have seizures and are considered therapy-resistant or refractory patients. The ultimate goal for the use of AEDs is complete cessation of seizures without side effects. Because of a narrow therapeutic index of AEDs, a complete understanding of its clinical pharmacokinetics is essential for understanding of the... -
Antinociception Effect and Mechanisms of Campanula Punctata Extract in the Mouse
Soo-HyunPark, Yun-BeomSim, Soon-SungLim, Jin-KyuKim, Jin-KooLee, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 6 285-289 (5 pages)
in the writhing test. However, naloxone (opioid receptor antagonist) or methysergide (5-HT serotonergic receptor antagonist) did not affect antinociception induced by Campanula punctata extract in the writhing test. Our results suggest that Campanula punctata extract shows an antinociceptive property in various pain models. Furthermore, this antinociceptive effect of Campanula punctata extract may be mediated by Ձ2-adrenergic receptor, but not opioidergic and serotonergic receptors. -
R-type Calcium Channel Isoform in Rat Dorsal Root Ganglion Neurons
ZhiFang, JaeHongHwang, JoongSooKim, SungJunJung, SeogBaeOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 7 45-49 (5 pages)
R-type Cav2.3 high voltage-activated Ca2+ channels in peripheral sensory neurons contribute to pain transmission. Recently we have demonstrated that, among the six Cav2.3 isoforms (Cav2.3a∼Cav2.3e), the Cav2.3e isoform is primarily expressed in trigeminal ganglion (TG) nociceptive neurons. In the present study, we further investigated expression patterns of Cav2.3 isoforms in the dorsal root ganglion (DRG) neurons. As in TG neurons, whole tissue RT-PCR analyses revealed the presence of two... -
Rapid Induction of mRNA for Prostaglandin H Synthase in Ovine Meningeal Fibroblasts
MyeongJinNam, ClaraThore, DavidBusija 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 5 435-441 (7 pages)
We examined effects of interleukin 1α (IL1α) and phorbol 12, 13 dibutyrate (PDB), an activator of protein kinase C, on mRNA for Prostaglandin H synthase (PGHS) and prostanoid production in cultured ovine meningeal fibroblasts. Immuno- and morphologically-identified fibroblasts were derived from cerebral cortex and white matter from fetal lambs (approximately 120 days gestation) and grown to confluence on glass coverslips in 12 well plates. Levels of prostaglandin F2α and the stable... -
Effects of Morphine on Somatosyrnpathetic Reflex and Arterial Blood Pressure Response Evoked by Stimulation of Peripheral Nerves
Huh, Min-Gang, Yan, Hai-Dun, Lim, Won-Il, Kim, Jun 대한생리학회 대한생리학회지 13 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 2호 13 309-321 (13 pages)
In the present study, the relationship between the somatosympathetic reflexes and arterial blood pressure responses to electrical stimulation of the peripheral nerve was investigated in cats anesthetized with α-chloralose. Single sympathetic postganglionic fiber activities were recorded from the hindlimb muscle and skin nerves and also from the cervical and abdominal sympathetic chains. Effects of the morphine on responses of the sympathetic nerve and arterial blood pressure to activation of... -
아디포넥틴(adiponectin) 관련 연구논문 분석
변영순 한국기초간호학회 Journal of Korean Biological Nursing Science 11 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2010, Vol.12 No.3 7 175-185 (11 pages)
지방조직은 에너지원으로 지방을 축적할 뿐 아니라 생물활 성 단백질을 분비하는 내분비기관으로서 지방조직에서 분비 된 후 기타 기관에서 활성을 갖는 단백질을 아디포카인(adipokine) 또는 아디포사이토카인(adipocytokine)이라고 한다 (Funahashi et al., 1999). 아디포카인은 종양괴사인자-a (tumor necrosis factor-a, TNF-a), 렙틴(leptin), 인터루킨- 6 (interleukin-6, IL-6), 레지스틴(resistin), 아디포넥틴(aditonectin) 등을 포함하고 있으며(Funahashi et al., 1999), 이 중 아디포넥틴은 1995년 Scherer, Williams,... -
등척성 코어근육 강화운동이 초보골퍼의 스윙에 미치는 영향
진영완, 이상원 한국웰니스학회 한국웰니스학회지 10 Pages
한국웰니스학회 한국웰니스학회지 2014, 제 9권 3호 15 189-198 (10 pages)
본 연구의 목적은 12 주간의 코어 근육 강화 운동을 통해 골프스윙의 기술적 변화가 일어나는지 남자 초보골퍼 11명에게 적 용하여 알아보았다. 3D 영상분석 시스템을 통해 각속도, 각가속도, 선속도, 선가속도, 코어 근력, 볼 비거리를 사전 및 사후 분석 하였다. 결과는 다음과 같다. 임팩트 시 각속도 및 각가속도는 운동전과 후의 결과 모두 유의한 차이를 보이지 않았다. 임팩트 시 선속도 및 선가속도는 선속도에서 X, Y, 축은 유의한 증가를 보였고, Z축은 유의하게 감소하였다(p <0.05, P <0.001, P <0.05). 선 가속도는...
