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201.

Developmental Disability Animal Model Based on Neonatal Lipopolysaccharide with Altered 5-HT Function

JaeGooKim, MinSooKim, SeoulLee, GunTaeKim, JongDooLee, DongGooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 6 113-119 (7 pages)

JaeGooKim, MinSooKim, SeoulLee, GunTaeKim, JongDooLee, DongGooKim 저
...
- 3,000원
Developmental disability shows life-long behavioral abnormality with no significant physical malformation. This study was undertaken to develop an animal model for developmental disability by using two-factor approach. Lipopolysaccharide (LPS), a bacterial toxin, and NAN-190, a 5-HT1A receptor antagonist, were administered to Sprague-Dawley rats on postnatal day (PND) 5 to induce inflammation and an altered 5-HT system, respectively. Long-term alteration of behavior occurred in the drug-treated...
202.

Sweating by Exercise Controls Body Temperature through Increase of Interleukin-1beta

Jun-SangBae, Young-OhShin, Jeong-BeomLee, HyunSeok, Young-KiMin, Hun-MoYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.5 2 231-234 (4 pages)

Jun-SangBae, Young-OhShin, Jeong-BeomLee, HyunSeok, Young-KiMin, Hun-MoYang 저
...
- 1,500원
This study was designed to investigate the expression and production of interleukin-1beta (IL-1β) in human peripheral blood of trained runners and untrained controls after temporary moderate intensity exercise. Male long-distance trained runners (TR) and untrained sedentary control subjects (SED) ran for 1 h at 70% of heart rate reserve (HRR). IL-1β gene and protein expressions were significantly higher in TR than those with SED at all 3 intervals examined independently. Significant increases...
203.

Nitric Oxide Donor, NOR-3, Increased Expression of Cyclooxygenase-2, but not of Cyclooxygenase-1 in Cultured VSMC

DongHyupLee, JiEunPark, YoungJinKang, KwangYounLee, HyoungChulChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.3 8 161-165 (5 pages)

DongHyupLee, JiEunPark, YoungJinKang, KwangYounLee, HyoungChulChoi 저
...
- 1,500원
NO and cyclooxygenase-2 (COX-2) are contributes to vascular inflammation induced by various stimulation. The mechanism, which explains a linkage between NO and COX-2, could be of importance in promoting pathophysiological conditions of vessel. We investigated the effects of NO donors on the COX-1 and COX-2 mRNA/protein expression, as well as the nitrite production in culture medium of vascular smooth muscle cell (VSMC). VSMC was primarily cultured from thoracic aorta of rat. In this experiments,...
204.

Effects of Chlorhexidine digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes

Hye-OckJang, Dong-WonKim, Byeong-IllKim, Hong-GuSim, Young-HoLee, Jong-HwaLee, Jung-HaBae, Moon-KyoungBae, Tae-HyukKwon, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 3 83-88 (6 pages)

Hye-OckJang, Dong-WonKim, Byeong-IllKim, Hong-GuSim, Young-HoLee, Jong-HwaLee, Jung-HaBae, Moon-KyoungBae, Tae-HyukKwon, IlYun 저
...
- 3,000원
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids extracted from cultured Porphyromonas gingivalis outer membranes (OPG). The anthroyloxy probes were located at a graded series of depths inside a membrane, depending on its substitution position (n) in the aliphatic chain. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used...
205.

Effects of Chlorhexidine Digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic Acid in Porphyromonas ginginvalis Outer Membranes

Hye-OckJang, Seong-KweonCha, ChangLee, Min-GakChoi, Sung-RyulHuh, Sang-HunShin, In-KyoChung, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 2 125-130 (6 pages)

Hye-OckJang, Seong-KweonCha, ChangLee, Min-GakChoi, Sung-RyulHuh, Sang-HunShin, In-KyoChung, IlYun 저
...
- 3,000원
The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine the effect of chlorhexidine digluconate on differential rotational mobility of different positions of the number of membrane bilayer phospholipid carbon atoms. The six membrane components differed with respect to 2, 3, 6, 9, 12, and 16-(9-anthroyloxy)stearic acid (2-AS, 3-AS, 6-AS,...
206.

Effects of Calcium Channel Blockers on Porcine Cardiac and Coronary Arterial Function in Ischemia-Reperfusion

YungHongBaik, HyunKook, SunHeePark, SeongJooJeong, DongYoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 7 587-595 (9 pages)

YungHongBaik, HyunKook, SunHeePark, SeongJooJeong, DongYoonLim 저
...
- 3,000원
This study was designed to investigate effects of calcium antagonists on endothelial and neuronal dysfunction of right coronary artery (RCA) induced by ischemia- reperfusion in anesthetized, open-chest pigs. After reperfusion, pigs were sacrificed and the RCA was rapidly dissected for in vitro experiments. Experimental groups were divided into 4 groups: control (C-RCA), ischemia-reperfusion only (I-RCA), verapamil infusion (VI-RCA) and nifedipine infusion (NI-RCA) group, respectively. The...
207.

Minimal Amount of Insulin Can Reverse Diabetic Heart Function Sarcoplasmic Reticulum Ca2+ Transport and Phospholamban Protein Expression

HaeWonKim, YongSunCho, YunSongLee, EunHeeLee, HeeRanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 7 175-182 (8 pages)

HaeWonKim, YongSunCho, YunSongLee, EunHeeLee, HeeRanLee 저
...
- 3,000원
In the present study, the underlying mechanisms for diabetic functional derangement and insulin effect on diabetic cardiomyopathy were investigated with respect to sarcoplasmic reticulum (SR) Ca2⁢-ATPase and phospholamban at the transcriptional and translational levels. The maximal Ca2⁢ uptake and the affinity of Ca2⁢-ATPase for Ca2⁢ were decreased in streptozotocin-induced diabetic rat cardiac SR, however, even minimal amount of insulin could reverse both parameters....
208.

Role of Phospholipase A2 in Oxidant-induced Alteration in Phosphate Transport in Primary Cultured Rabbit Renal Proximal Tubule Cells

KwonMooPark, SunHeeKo, JaeSukWoo, JinSupJung, SangHoLee, YongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 8 601-609 (9 pages)

KwonMooPark, SunHeeKo, JaeSukWoo, JinSupJung, SangHoLee, YongKeunKim 저
...
- 3,000원
The present study was undertaken to examine the role of phospholipase A2 (PLA2) in oxidant-induced inhibition of phosphate transport in primary cultured rabbit renal proximal tubule cells. Uptakes of phosphate and glucose were dose-dependently inhibited by an oxidant t-butylhydroperoxide (tBHP), and the significant inhibition appeared at 0.025 mM of tBHP, whereas tBHP-induced alterations in lipid peroxidation and cell viability were seen at 0.5 mM. tBHP stimulated arachidonic acid (AA) release...
209.

The Staging of Major Mood Disorders

Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)

Ather Muneer, Rana Mazommil 저
...
- 4,100원
Objective_Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods_In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like “major depressive disorder and staging,” “bipolar disorder and neuroprogression,” etc. To incorporate the latest findings the search was limited to the last 10 years. Both original and review articles were...
210.

뇌종양 수술 후 방사선치료에 의해 발생한 이차성 조증

유범희, 우종민, 신형진, 김승태 대한신경정신의학회 신경정신의학 6 Pages

대한신경정신의학회 신경정신의학 1997, 제 36권 제 5호 17 942-947 (6 pages)

유범희, 우종민, 신형진, 김승태 저
...
- 3,000원
국소적 대뇌 병변에 의한 이차성 조증은 드물게 보고되어 왔다. 저자들은 정신과적 병력이 없던 사람이 좌 측 측두엽 뇌종양의 종양 절제술을 받은 뒤 별다른 문제없이 잘 지내다가 수술 후 방사선치료를 받은지 약 4개월만에 조증 삽화를 보인 증례를 경험하였다. 정위적 조직검사 결과 이는 방사선치료에 의한 후유증으로 지연성 손상이 일어나 우측 해마 부위가 괴사되었기 때문인 것으로 밝혀졌다. 본 증례를 통해 저자들은 이차 성 조증의 발병과 우측 해마 부위의 병변이 밀접하게 관련되어 있음을 확인할 수 있었다. 이처럼 이차성...

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