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2121.

Neurotrophic and Neuritogenic Effects of Water Extracts of Rhizoma of Coptis chinensis Franch in PC12 Cells

Gee-YounKwon, Byung-KilChoe, Soo-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 9 175-179 (5 pages)

Gee-YounKwon, Byung-KilChoe, Soo-KyungKim 저
...
- 1,500원
Coptis chinensis (CC) is one of the traditional herbs used in Oriental medicine for the treatment of gastrointestinal disorders, anxiety, and insomnia. In this study, neurotrophic and neuritogenic effects of CC on rat pheochromocytoma (PC12) cells were evaluated. Pretreatment of PC12 cells with water extracts of CC (120μg /ml) produced considerable outgrowth of neurites that is comparable to the effect of nerve growth factor (NGF). Therefore, neurite outgrowth was quantified and expression of...
2122.

Acute Effect of Alcohol and Nicotine on 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in Dorsal and Median Raphe of Rats

Mi-HyeonJang, Min-ChulShin, Hyun-KyungChang, Taeck-HyunLee, Khae-HawnKim, Youn-JungKim, Chang-JuKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.1 2 5-8 (4 pages)

Mi-HyeonJang, Min-ChulShin, Hyun-KyungChang, Taeck-HyunLee, Khae-HawnKim, Youn-JungKim, Chang-JuKim 저
...
- 1,500원
Alcohol abuse and cigarette smoking have been on the rise worldwide and it has been reported that alcohol and nicotine influence serotonergic neuronal activity in the dorsal raphe. Serotonin (5-hydroxytryptamine, 5-HT) has been implicated in the pathophysiology of various neuropsychiatric disorders. In the present study, the effects of alcohol and nicotine on the synthesis of 5-HT and the expression of tryptophan hydroxylase (TPH), the rate limiting enzyme of 5-HT synthesis, in the dorsal and...
2123.

Interactions between Estradiol-17β-BSA and Calcitropic Hormones in Ca2+ Uptake in Renal Proximal Tubule Cells

HoJaeHan, YeunHeeLee, EunJuSeo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.5 5 261-268 (8 pages)

HoJaeHan, YeunHeeLee, EunJuSeo 저
...
- 3,000원
The aim of the present study was to investigate the interaction of estradiol-17β-bovine serum albumin (E2-BSA) and calcitropic hormones, such as parathyroid hormone, calcitonin, and vitamin D, in regulation of Ca2⁢ uptake in primary cultured renal proximal tubule cells. Statistically significant increase in Ca2⁢ uptake was found from 2 hours after E2-BSA (10⁣9 M) treatment, while estradiol-17β (10⁣9 M) did not affect. Treatment of the cells with E2-BSA (10⁣9 M)...
2124.

The Protective Effect of Melatonin Administration against Adriamycin-induced Cardiotoxicity in Rats

JinHan, ChungheeKim, NariKim, JuheePark, YoungchurlYang, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.4 6 333-342 (10 pages)

JinHan, ChungheeKim, NariKim, JuheePark, YoungchurlYang, EuiyongKim 저
...
- 3,000원
Adriamycin is a commonly used chemotherapeutic agent for cancer, including acute leukemia, lymphoma, and a number of solid human tumors. However, recent studies have recognized severe cardiotoxicity after an acute dose, which are likely the result of generation of free radicals and lipid peroxidation. Therefore, the clinical uses of adriamycin have been limited. Melatonin, the pineal gland hormone known for its ability to modulate circardian rhythm, has recently been studied in its several...
2125.

Block of ATP-Sensitive K Channels Expressed in Xenopus Oocytes by Dimethyl Sulfoxide

JinBongParkSooWanChae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 6 157-163 (7 pages)

JinBongParkSooWanChae 저
...
- 3,000원
The effects of dimethyl sulfoxide (DMSO) were studied in two groups of Xenopus oocytes, one expressing ATP sensitive K (KATP) channel comprised of sulfonylurea receptor SUR1 and inwardly rectifying K channel subunit Kir6.2, and the other expressing renal KATP channel ROMK2. At concentrations of 0.3∼10% (vol/vol) DMSO inhibited whole cell Kir6.2/SUR1 currents elicited by bath application of sodium azide (3 mM) in a concentration-dependent manner. The inhibition constant and Hill coefficient...
2126.

DAMGO, a μ-Opioid Agonist and Cholecystokinin-Octapeptide Have Dual Modulatory Effects on Capsaicin-Activated Current in Rat Dorsal Root Ganglion Neurons

Su-YongEun, JimokKim, JihyeLee, SungJunJung, JooMinPark, YunKyungPark, DongkwanKim, SangJeongKim, JiyeonKwak, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 10 71-78 (8 pages)

Su-YongEun, JimokKim, JihyeLee, SungJunJung, JooMinPark, YunKyungPark, DongkwanKim, SangJeongKim, JiyeonKwak, JunKim 저
...
- 3,000원
Capsaicin, a pungent ingredient of hot pepper, elicits an intense burning pain when applied cutaneously and intradermally. Activation of capsaicin-gated channel in C-type dorsal root ganglion (DRG) neurons produces nonselective cationic currents. Although electrophysiological and biochemical properties of capsaicin-activated current (ICAP) were studied, the regulatory mechanism and intracellular signaling pathway are still unclear. In the present study, we investigated the modulations of ICAP...
2127.

Cardiac Response to Head-Out Water Immersion in Man

JangKyuChoi, Won-KunPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 10 253-261 (9 pages)

JangKyuChoi, Won-KunPark 저
...
- 3,000원
Head-out water immersion induces marked increase in the cardiac stroke volume. The present study was undertaken to characterize the stroke volume change by analyzing the aortic blood flow and left ventricular systolic time intervals. Ten men rested on a siting position in the air and in the water at 34.5oC for 30 min each. Their stroke volume, heart rate, ventricular systolic time intervals, and aortic blood flow indices were assessed by impedance cardiography. During immersion, the stroke...
2128.

Temporal Changes in Neuronal Activity of the Bilateral Medial Vestibular Nuclei Following Unilateral Labyrinthectomy in Rats

ByungRimPark, MoonYoungLee, MinSunKim, SungHoLee, HanJoNa, NamYongDoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 4 481-490 (10 pages)

ByungRimPark, MoonYoungLee, MinSunKim, SungHoLee, HanJoNa, NamYongDoh 저
...
- 3,000원
To investigate the changes in the responses of vestibular neurons with time during vestibular compensation, the resting activity and dynamic responses of type I and II neurons in the medial vestibular nuclei to sinusoidal angular acceleration were recorded following unilateral labyrinthectomy (ULX) in Sprague-Dawley rats. The unitary extracellular neuronal activity was recorded from the bilateral medial vestibular nuclei with stainless steel microelectrodes of 3∼5 MΩ before ULX, and 6, 24,...
2129.

Role of Phospholipase A2 in Hypoxia-Induced Renal Cell Injury

WonRakChoi, SunHeeKo, SuInCho, JaeSukWoo, JinSupJung, SangHoLee, YongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 12 93-100 (8 pages)

WonRakChoi, SunHeeKo, SuInCho, JaeSukWoo, JinSupJung, SangHoLee, YongKeunKim 저
...
- 3,000원
The present study was designed to assess the roles of PLA2 activation and arachidonic acid (AA) metabolites in hypoxia-induced renal cell injury. Hypoxia increased LDH release in a dose-dependent manner in rabbit renal cortical slices, and this increase was significant after 20-min hypoxia. The hypoxia-induced LDH release was prevented by amino acids, glycine and alanine, and extracellular acidosis (pH 6.0). Buffering intracellular Ca2⁢ by a chelator, but not omission of Ca2⁢ in the...
2130.

The Inhibitory Mechanism of Aloe Glycoprotein (NY945) on the Mediator Release in the Guinea Pig Lung Mast Cell Activated with Antigen-Antibody Complexes

JaiYoulRo, ByungChulLee, MyungHeeChung, SeungKiLee, ChungKiSung, KyungHwanKim, YoungInPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 15 119-131 (13 pages)

JaiYoulRo, ByungChulLee, MyungHeeChung, SeungKiLee, ChungKiSung, KyungHwanKim, YoungInPark 저
...
- 4,200원
It has been reported that the g1ycoprotein extracted from A10e has strong anti-inflammatory response， However， there has been no research report yet about the effect of A10e on allergic hypersensitivity reactivity， By using guinea pig 1ung mast cells， this study aimed to examine the effects of A10e g1ycoprotein (NY945) on the mediator re1eases caused by mast cell activation， and a1so aimed to assess the effects of NY945 on the mechanism of mediator re1eases in the mast cell activation. We...

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