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211.

Modulatory Effect of the Tyrosine Kinase and Tyrosine Phosphatase on the ACh-activated K+ Channel in Adult Rat Atrial Cells

Chang, Kyeong-Jae, Rhie, Sang-Ho, Heo, Ilo, Kim, Yang-Mi, Haan, Jae-Hee, Hong, Seong-Geun 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 3 209-218 (10 pages)

Chang, Kyeong-Jae, Rhie, Sang-Ho, Heo, Ilo, Kim, Yang-Mi, Haan, Jae-Hee, Hong, Seong-Geun 저
...
- 3,000원
Acetylcholine (ACh) activates the inwardly rectifying muscarinic K+ channel in rat atrial cells via pertussis toxin (PTX)-sensitive G-protein (Gk) coupled with the muscarinic receptor (mAChR). Although this K+ (KACh) channel function has reported to be modulated by the phosphorylation process, a kinase and phosphatase involved in these processes are still unclear. Since either PKA or PKC was not effective on this ATP-modulation, the present study examined the possible involvement of the protein...
212.

Inositol 1,4,5-Trisphosphate-induced Increase in Ca2+-ATPase Activity in the Microsomes of Tracheal Epithelial Cells

Cho, Hyoung-Jin, Park, Sung-Shin, Kim, Young-Kee 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 9 269-278 (10 pages)

Cho, Hyoung-Jin, Park, Sung-Shin, Kim, Young-Kee 저
...
- 3,000원
Membrane vesicles were prepared by differential centrifugation from epithelial cells of porcine trachea. Total activity of microsomal ATPases was measured spectrophotometrically by a coupled enzyme assay. The steady-state activity of the enzyme was 329±10 nmol/min mg protein. Thapsigargin, a specific antagonist of intracellular Ca2+-ATPase, inhibited about 50% of the activity, leaving 178±18 nmol/min .mg protein (n=6), indicating that the Ca2+-ATPase is one of the major microsomal ATPases....
213.

Contractile and Electrical Responses of Guinea-pig Gastric Smooth Muscle to Bradykinin

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 5 233-242 (10 pages)

Kim, Chul-Soo, Jun, Jae-Yeoul, Kim, Sung-Joon, So, In-Suk, Kim, Ki-Whan 저
...
- 3,000원
The nonapeptide bradykinin has been shown to exhibit an array of biological activities including relaxation/contraction of various smooth muscles. In order to investigate the effects of bradykinin on the contractility and the electrical activity of antral circular muscle of guinea-pig stomach, the isometric contraction and membrane potential were recorded. Also, using standard patch clamp technique, the Ca2+-activated K currents were recorded to observe the change in cytosolic Ca2+...
214.

Effect of Preconditioning Ischemia on Endothelial Dysfunction Produced by Ischemia-Reperfusion in Rabbit Coronary Artery

Suh, Suk-Hyo, Park, Yee-Tae, Kim, Woong-Heum, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 5 51-60 (10 pages)

Suh, Suk-Hyo, Park, Yee-Tae, Kim, Woong-Heum, Kim, Ki-Whan 저
...
- 3,000원
This study was designed to test whether or not 1) ischemia-reperfusion attenuates endothelium-dependent relaxation of coronary arteries and 2) preconditioning protects the arterial endothelium from ischemia-reperfusion injury. In anesthetized open chest rabbits, branches of the left circumflex artery were exposed to different combinations of the experimental conditions; ischemia (15 minutes), ischemia (15 minutes)-reperfusion (10 minutes), preconditioning ischemia, and pre-conditioning fellowed...
215.

Properties of Single K+ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 2 13-28 (16 pages)

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 저
...
- 4,500원
single K+ channels of skeletal muscle from the rat and frog were into planar lipid bilayers and their properties were studied. Fusion was induced by an osmotic gradient. Of the four types of K+ channels recorded, the two most frequently observed were a voltage and Ca2+-activated K+ channel and a K+ channel with a prominent conductance substate. The first K+ channel was identified as the large Ca2+-activated K+ (BK) channel because the open-state probability was increased with depolarization...
216.

Ca2+-activated Cl- Current in Gastric Antral Myocytes

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 4 143-150 (8 pages)

Lee, Moo-Yeol, Bang, Hyo-Weon, Uhm, Dae-Yong, Rhee, Sang-Don 저
...
- 3,000원
The whole-cell mode of the patch clamp technique was used to study Ca2+-activated Cl- current (IClCa) in gastric antral myocytes. Extracellular application of caffeine evoked Ca2+-activated current. In order to isolate the chloride current from background current, all known systems were blocked with specific blockers. The current-voltage relationship of caffeine-induced current showed outward rectification and it reversed at around ECl-. The shift of reversal potential upon the alteration of...
217.

Effects of Lemakalim, a Potassium Channel Opener, on the Contractility and Electrical Activity of the Antral Circular Muscle in Guinea-Pig Stomach

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 4 37-50 (14 pages)

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 저
...
- 4,300원
Synthetic potassium channel openers (KCOs) are agents capable of opening K-channels in excitable cells. These agents are known to have their maximal potency in the smooth muscle tissue, especially in the vascular smooth muscle. Much attention has been focused on the type of K-channel that is responsible for mediating the effects of KCOs. As the KCO-induced changes are antagonized by glibenclamide, an KATP (ATP-sensitive K-channel) blocker in the pancreatic β-cell, KATP was suggested to be the...
218.

Effect of Dopamine on the Ca2+-dependent K+ currents in Isolated Single Gastric Myocytes of the Guinea-pig

Rhee, Poong-Lyul, Lee, Sang-Jin, Kim, Sung-Joon, So, In-Suk, Hwang, Sang-Ik, Kim, Ki-Whan 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1993, 제 27권 제 2호 3 139-150 (12 pages)

Rhee, Poong-Lyul, Lee, Sang-Jin, Kim, Sung-Joon, So, In-Suk, Hwang, Sang-Ik, Kim, Ki-Whan 저
...
- 4,100원
We have reported that dopamine potentiates spontaneous contractions dose-dependently in guinea-pig antral circular muscle strips (Hwang et al, 1991). To clarify the underlying excitatory mechanism of dopamine on the gastric smooth muscle, the effects of dopamine on voltage-dependent Ca2+ currents and Ca2+ -dependent K+ currents were observed in enzymatically dispersed guinea-pig gastric myocytes using the whole-cell voltage-clamp technique. Experiments were also done using isometric tension...
219.

Effect of Various Divalent Ions on the Calcium Current of Adrenal Medullary Chromaffin Cells in the Rat

Kim, Jun, Leem, Chae-Hun, Kim, Sang-Jeong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 2호 2 113-122 (10 pages)

Kim, Jun, Leem, Chae-Hun, Kim, Sang-Jeong 저
...
- 3,000원
to study Ca2+ current with external and internal solutions that could effectively isolate VDCC currents (NMG in external and TEA and Cs2+ in internal solution). The voltage dependence and the inactivation time course of VDCC in our cells were identical to those of bovine chromaffin cells. A persistent inward current was first activated by depolarizing step pulse from the holding potential (H.P.) of -80 mV to -40 mV, increased to maximum amplitude at around +10 mV, and became smaller with...
220.

Cl--sensitive Component of Ca2+-activated Tail Current in Rabbit Atrial Myocytes

Park, Choon-Ok, So, In-Suk, Ho, Won-Kyung, Kim, Woo-Gyeum, Earm, Yung-E 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1992, 제 26권 제 1호 3 27-36 (10 pages)

Park, Choon-Ok, So, In-Suk, Ho, Won-Kyung, Kim, Woo-Gyeum, Earm, Yung-E 저
...
- 3,000원
We used the whole cell patch clamp technique to examine the ionic basis for the tail current after depolarizing pulse in single atrial myocytes of the rabbit. We recorded the tail currents during various repolarizations after short depolarizing pulse from a holding potential of -70 mV. The potassium currents were blocked by external 4-aminopyridine and replacement of internal potassium with cesium. The current was reversed to the outward direction above +10 mV. High concentrations of...

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