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221.

Block of hERG K＋ Channel by Classic Histamine H1 Receptor Antagonist Chlorpheniramine

Hee-KyungHong, Su-HyunJo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 12 215-220 (6 pages)

Hee-KyungHong, Su-HyunJo 저
...
- 3,000원
Chlorpheniramine is a potent first-generation histamine H1 receptor antagonist that can increase action potential duration and induce QT prolongation in several animal models. Since block of cardiac human ether-a-go-go-related gene (hERG) channels is one of leading causes of acquired long QT syndrome, we investigated the acute effects of chlorpheniramine on hERG channels to determine the electrophysiological basis for its proarrhythmic potential. We examined the effects of chlorpheniramine on...
222.

Decreased Expression of PTEN in Olfactory Bulb of Rat Pub after Naris Closure

JaeyoungCho, Sang-HyunLee, GeonHeeLee, WanjooChun, Yee-TaePark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 3 17-20 (4 pages)

JaeyoungCho, Sang-HyunLee, GeonHeeLee, WanjooChun, Yee-TaePark 저
...
- 1,500원
PTEN (phosphatase and tensin homolog) is a dual specific phosphatase antagonizing phosphoinositide 3-kinase activity, and has first been cloned as a tumor suppressor for glioma. Although the role of PTEN as a tumor suppressor has been well studied, little is known about signaling mechanisms regulating expression and/or activity of PTEN in the central nervous system. In this study, we investigated whether PTEN expression is regulated by sensory deprivation. P5 rat pups were unilaterally...
223.

Roles of Ca2+-Activated K+ Conductances on Spontaneous Firing Patterns of Isolated Rat Medial Vestibular Nucleus Neurons

SangWooChun, JaeWooJun, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 1 1-8 (8 pages)

SangWooChun, JaeWooJun, ByungRimPark 저
...
- 3,000원
To investigate the contributions of intrinsic membrane properties to the spontaneous activity of medial vestibular nucleus (MVN) neurons, we assessed the effects of blocking large and small calcium-activated potassium channels by means of patch clamp recordings. Almost all the MVN neurons recorded in neonatal (P13∼P17) rat were shown to have either a single deep after-hyperpolarization (AHP; type A cells), or an early fast and a delayed slow AHP (type B cells). Among the recorded MVN cells,...
224.

Effects of Exogenous ATP on Calcium Mobilization and Cell Proliferation in C6 Glioma Cell

Eun-JungLee, SeokHoCha, WoonKyuLee, Kweon-HaengLee, Sang-BokLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 3 419-425 (7 pages)

Eun-JungLee, SeokHoCha, WoonKyuLee, Kweon-HaengLee, Sang-BokLee 저
...
- 3,000원
To clarify the effect of extracellular ATP in cultured C6 glioma cells, ATP-induced cytosolic free calcium ([Ca2⁢]i) mobilization and cell proliferation were investigated. ATP-induced [Ca2⁢]i increased in a dose-dependent manner (10⁣7 M∼10⁣3 M). ATP-induced [Ca2⁢]i increases were slightly slowed in extracellular calcium-free conditions especially in sustained phase. ATP-induced [Ca2⁢]i increment was also inhibited by the pretreatment of U73122, a...
225.

정신분열증에서의 정보처리와 그 신경해부학 ᅳ정신병리의 신경과학적 이해를 위해ᅳ

이성훈 대한신경정신의학회 신경정신의학 23 Pages

대한신경정신의학회 신경정신의학 1991, 제 30권 제 4호 2 629-651 (23 pages)

이성훈 저
...
- 5,200원

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