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241.

Clinical pharmacokinetics of norfloxacin-glycine acetate after intravenous and oral administration in pigs

Zhi-Qiang Chang, Byung-Chol Oh, Jong-Choon Kim, Kyu-Shik Jeong, Myung-Heon Lee, Hyo-In Yun, Mi-Hyun Hwang, Seung-Chun Park* 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 6 353-356 (4 pages)

Zhi-Qiang Chang, Byung-Chol Oh, Jong-Choon Kim, Kyu-Shik Jeong, Myung-Heon Lee, Hyo-In Yun, Mi-Hyun Hwang, Seung-Chun Park* 저
...
- 1,500원
The pharmacokinetics and dosage regimen of norfloxacin-glycine acetate (NFLXGA) was investigated in pigs after a single intravenous (i.v.) or oral (p.o.) administration at a dosage of 7.2 mg/kg body weight. After both i.v. and p.o. administration, plasma drug concentrations were best fitted to an open two-compartment model with a rapid distribution phase. After i.v. administration of NFLXGA, the distribution (t1/2■)and elimination half-life (t1/2■) were 0.36 ± 0.07 h and 7.42 ± 3.55...
242.

Effectiveness of 99mTc-tetrofosmin for assessment of heart functions in micropigs

Min Young Lee, Sang Hun Lee, Jae Hong Park, Jung Sun Heo, Yu Jin Lee, Han Na Suh, Jung Jun Min, Young Soon Seo, Ho Jae Han 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 3호 4 223-227 (5 pages)

Min Young Lee, Sang Hun Lee, Jae Hong Park, Jung Sun Heo, Yu Jin Lee, Han Na Suh, Jung Jun Min, Young Soon Seo, Ho Jae Han 저
...
- 1,500원
This study examined the suitability of a nuclear imaging technique using 99mTc-tetrofosmin as an agent to assess the heart functions of healthy micropigs. The mean age of the pigs was 360 days (male), and the mean body weight was 35.3 kg ranging from 34.5-36 kg. There were no significant perfusion defects in any of the reconstructed images. Gated single-photon emission computed tomography imaging can be used to calculate the ventricular volume and ejection fraction (EF). In this case, an EF of...
243.

In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin

Doo Kim, Dorsey Kordick, Thomas Divers, Yung-Fu Chang 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 9 355-359 (5 pages)

Doo Kim, Dorsey Kordick, Thomas Divers, Yung-Fu Chang 저
...
- 1,500원
Antimicrobial susceptibility testing was conducted with 6 different spirochetal strains (4 strains of Leptospira spp. and 2 strains of Borrelia burgdorferi) against 3 antimicrobial agents, commonly used in equine and bovine practice. The ranges of MIC and MBC of amoxicillin against Leptospira spp. were 0.05-6.25 μg/ml and 6.25-25.0 μg/ml, respectively. And the ranges of minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of amoxicillin against B. burgdorferi...
244.

Pharmacokinetics, urinary excretion and dosage regimen of levofloxacin following a single intramuscular administration in cross bred calves

Vinod K. Dumka, Anil K. Srivastava 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 5 333-337 (5 pages)

Vinod K. Dumka, Anil K. Srivastava 저
...
- 1,500원
The pharmacokinetics and urinary excretion following single intramuscular administration of levofloxacin at a dose of 4 mg/kg was investigated in seven male cross bred calves. Appreciable plasma concentration of levofloxacin (0.38 ± 0.06 μg/ml) was detected at 1 min after injection and the peak plasma level of 3.07 ± 0.08 μg/ml was observed at 1 h. The drug level above MIC90 in plasma was detected up to 12 h after administration. Rapid absorption of the drug was also evident by the high...
245.

Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits

Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 10 151-155 (5 pages)

Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 저
...
- 1,500원
This study examined the effect of experimentally induced fever on the pharmacokinetics of cefepime (75 mg/kg BW) administered intramuscularly to six rabbits. The study was carried out in two consecutive phases separated by a two-week washout period. An infection was induced by an intravenous inoculation of 5 × 108 colony-forming units of Escherichia coli 24 h before the pharmacokinetic investigation. A quantitative microbiological assay was employed to measure the plasma cefepime concentrations...
246.

Experimental peritonitis induced by oral administration of indomethacin in Mongolian gerbils

Okjin Kim, Jin-Uk Lee 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 8 137-141 (5 pages)

Okjin Kim, Jin-Uk Lee 저
...
- 1,500원
The possibility of inducing peritoneal inflammation in three murine species (gerbils, rats and mice) via the oral administration of indomethacin was investigated with the overall aim of developing an experimental animal model for human peritonitis. Gerbils given high doses of indomethacin at a rate of 30 mg and 40 mg/kg body weight showed swelling of the abdomen, depression and dyspnea within 4 days after the treatment. The severity of the clinical symptoms increased with time. The animals were...
247.

Subcutaneous pharmacokinetics and dosage regimen of cefotaxime in buffalo calves (Bubalus bubalis)

Suresh Kumar Sharma, Anil Kumar Srivastava 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 4 119-122 (4 pages)

Suresh Kumar Sharma, Anil Kumar Srivastava 저
...
- 1,500원
The pharmacokinetics and dosage regimen of cefotaxime following its single subcutaneous administration (10 mg/ kg) were investigated in buffalo calves. Plasma and urine samples were collected over 10 and 24 h post administration, respectively. Cefotaxime in plasma and urine was estimated by microbiological assay technique using E. coli as test organism. The pharmacokinetic profiles fitted one-compartment open model. The peak plasma levels of cefotaxime were 6.48 ± 0.52 ?g/ml at 30 min and the...
248.

Simultaneous detection of Lawsonia intracellularis, Brachyspira hyodysenteriae and Salmonella spp. in swine intestinal specimens by multiplex polymerase chain reaction

Dong Kyun Suh, Jae Chan Song 대한수의학회 Journal of Veterinary Science 7 Pages

대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 10 231-237 (7 pages)

Dong Kyun Suh, Jae Chan Song 저
...
- 3,000원
A multiplex PCR assay was developed for the simultaneous detection of the etiologic agents associated with porcine proliferative enteropathies (PPE), swine dysentery (SD)and porcine salmonellosis (PS)in a single reaction using DNA from swine intestinal samples. Single and multiplex PCR amplification of DNA from Lawsonia intracellularis, Salmonella typhimurium and Brachyspira hyodysenteriae with each primer set produced fragments of the predicted size without any nonspecific amplification,...
249.

Studies on mastitis, milk quality and health risks associated with consumption of milk from pastoral herds in Dodoma and Morogoro regions, Tanzania

Esron D. Karimuribo, Lughano J. Kusiluka, Robinson H. Mdegela, Angolwisye M. Kapaga, Calvin Sindato, Dominic M. Kambarage 대한수의학회 Journal of Veterinary Science 9 Pages

대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 7 213-221 (9 pages)

Esron D. Karimuribo, Lughano J. Kusiluka, Robinson H. Mdegela, Angolwisye M. Kapaga, Calvin Sindato, Dominic M. Kambarage 저
...
- 3,000원
The prevalence of mastitis, milk quality and health risks associated with milk consumption were investigated on 96 randomly selected traditional herds in Dodoma rural and Mvomero districts of Tanzania. Mastitis was investigated based on clinical signs, microbiology and California mastitis test (CMT), while milk quality was evaluated using total viable count (TVC)and total coliform count (TCC). Animals were tested for tuberculosis using a single comparative intradermal tuberculin test. The...
250.

Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens

M. Singh, C. Varshneya, R. S. Telang, A. K. Srivastava 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 4 197-200 (4 pages)

M. Singh, C. Varshneya, R. S. Telang, A. K. Srivastava 저
...
- 1,500원
had significantly higher area under curve (AUC), area under the first moment of plasma drug concentration-time curve (AUMC)and mean residential time (MRT). Prior treatment of P.longum significantly reduced elimination rate constan(&bgr;)and increased elimination half life (t1/2&bgr;). The total body clearance (ClB) reduced by 21%whereas total duration of pharmacological effect (td)increased by 29%. The treatment with P. longum reduced loading and maintenance dose by 33.3 and 39%, respectively.

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